9QU1

Crystal structure of the human RalGAPA2 N-terminal domain with human kappaB-Ras1

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0005829	cellular_component	cytosol
C	0010803	biological_process	regulation of tumor necrosis factor-mediated signaling pathway
C	0032484	biological_process	Ral protein signal transduction
C	0032794	molecular_function	GTPase activating protein binding
C	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
C	0043129	biological_process	surfactant homeostasis
C	0048286	biological_process	lung alveolus development
F	0000166	molecular_function	nucleotide binding
F	0003924	molecular_function	GTPase activity
F	0005525	molecular_function	GTP binding
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005829	cellular_component	cytosol
F	0010803	biological_process	regulation of tumor necrosis factor-mediated signaling pathway
F	0032484	biological_process	Ral protein signal transduction
F	0032794	molecular_function	GTPase activating protein binding
F	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
F	0043129	biological_process	surfactant homeostasis
F	0048286	biological_process	lung alveolus development

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Region: {"description":"Interactions with NFKBIA and NFKBIB"}

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Motif: {"description":"Effector region"}

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

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