9IZN
Crystal structure of HKU1A RBD bound to TMPRSS2
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| B | VAL292-CYS297 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| B | ASP435-VAL446 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FPCYAGH |
| Chain | Residue | Details |
| A | PHE672-HIS678 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CInpsnw.CDgvsHCpgg.EDEnr...C |
| Chain | Residue | Details |
| B | CYS126-CYS148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| A | ASN355 | |
| A | ASN433 | |
| A | ASN454 | |
| A | ASN470 | |
| A | ASN564 | |
| A | ASN666 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system => ECO:0000305|PubMed:38964326 |
| Chain | Residue | Details |
| B | ASP345 | |
| B | SER441 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37990007, ECO:0000269|PubMed:38964326, ECO:0007744|PDB:7XYD, ECO:0007744|PDB:7Y0E, ECO:0007744|PDB:7Y0F, ECO:0007744|PDB:8HD8, ECO:0007744|PDB:8S0L |
| Chain | Residue | Details |
| B | ASN131 | |
| B | ASP134 | |
| B | VAL136 | |
| B | ASP144 | |
| B | GLU145 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:11245484, ECO:0000269|PubMed:38964328 |
| Chain | Residue | Details |
| B | GLN255 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:37990007, ECO:0000269|PubMed:38964326, ECO:0007744|PDB:7XYD, ECO:0007744|PDB:7Y0E, ECO:0007744|PDB:7Y0F, ECO:0007744|PDB:8HD8, ECO:0007744|PDB:8S0L, ECO:0007744|PDB:8S0M |
| Chain | Residue | Details |
| B | ASN213 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN249 |
