9IP2

Cryo-EM structure of the RNA-dependent RNA polymerase complex from Marburg virus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001172	biological_process	RNA-templated transcription
A	0003824	molecular_function	catalytic activity
A	0003924	molecular_function	GTPase activity
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0005524	molecular_function	ATP binding
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0006397	biological_process	mRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0019013	cellular_component	viral nucleocapsid
A	0030430	cellular_component	host cell cytoplasm
A	0032259	biological_process	methylation
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039689	biological_process	negative stranded viral RNA replication
A	0039697	biological_process	negative stranded viral RNA transcription
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport
A	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation
B	0006351	biological_process	DNA-templated transcription
B	0019013	cellular_component	viral nucleocapsid
B	0030430	cellular_component	host cell cytoplasm
B	0044423	cellular_component	virion component
B	0055085	biological_process	transmembrane transport
C	0006351	biological_process	DNA-templated transcription
C	0019013	cellular_component	viral nucleocapsid
C	0030430	cellular_component	host cell cytoplasm
C	0044423	cellular_component	virion component
C	0055085	biological_process	transmembrane transport
D	0006351	biological_process	DNA-templated transcription
D	0019013	cellular_component	viral nucleocapsid
D	0030430	cellular_component	host cell cytoplasm
D	0044423	cellular_component	virion component
D	0055085	biological_process	transmembrane transport
E	0006351	biological_process	DNA-templated transcription
E	0019013	cellular_component	viral nucleocapsid
E	0030430	cellular_component	host cell cytoplasm
E	0044423	cellular_component	virion component
E	0055085	biological_process	transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
B	PRO-279-ASN-262
A	PRO2489-ASN2506

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	184
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	125
Details	Domain: {"description":"VP35 IID","evidences":[{"source":"PROSITE-ProRule","id":"PRU01071","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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