9I6A

Crystal structure of human Cdc20 bound to synthetic D-box peptide D7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000776	cellular_component	kinetochore
A	0000922	cellular_component	spindle pole
A	0005515	molecular_function	protein binding
A	0005654	cellular_component	nucleoplasm
A	0005680	cellular_component	anaphase-promoting complex
A	0005813	cellular_component	centrosome
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0007094	biological_process	mitotic spindle assembly checkpoint signaling
A	0007346	biological_process	regulation of mitotic cell cycle
A	0008284	biological_process	positive regulation of cell population proliferation
A	0010997	molecular_function	anaphase-promoting complex binding
A	0016567	biological_process	protein ubiquitination
A	0031145	biological_process	anaphase-promoting complex-dependent catabolic process
A	0031915	biological_process	positive regulation of synaptic plasticity
A	0032991	cellular_component	protein-containing complex
A	0033597	cellular_component	mitotic checkpoint complex
A	0042826	molecular_function	histone deacetylase binding
A	0044784	biological_process	metaphase/anaphase transition of cell cycle
A	0045842	biological_process	positive regulation of mitotic metaphase/anaphase transition
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0050773	biological_process	regulation of dendrite development
A	0051445	biological_process	regulation of meiotic cell cycle
A	0090129	biological_process	positive regulation of synapse maturation
A	0097027	molecular_function	ubiquitin-protein transferase activator activity
A	1904668	biological_process	positive regulation of ubiquitin protein ligase activity
A	1905786	biological_process	positive regulation of anaphase-promoting complex-dependent catabolic process
A	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
A	1990757	molecular_function	ubiquitin ligase activator activity
A	1990949	biological_process	metaphase/anaphase transition of meiosis I

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. TGGGtsDrHIRIWNV

Chain	Residue	Details
A	THR373-VAL387

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Repeat: {"description":"WD 1","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	41
Details	Repeat: {"description":"WD 2","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	35
Details	Repeat: {"description":"WD 3","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	42
Details	Repeat: {"description":"WD 5","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	40
Details	Repeat: {"description":"WD 6","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	29
Details	Repeat: {"description":"WD 7","evidences":[{"source":"PubMed","id":"27120157","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27509861","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5G04","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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