9HJC

Cryo-EM structure of thiamine-bound human TPK1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004788	molecular_function	thiamine diphosphokinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006772	biological_process	thiamine metabolic process
A	0009229	biological_process	thiamine diphosphate biosynthetic process
A	0010510	biological_process	regulation of pyruvate decarboxylation to acetyl-CoA
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0030975	molecular_function	thiamine binding
A	0042802	molecular_function	identical protein binding
A	0141200	molecular_function	UTP thiamine diphosphokinase activity
B	0000166	molecular_function	nucleotide binding
B	0004788	molecular_function	thiamine diphosphokinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006772	biological_process	thiamine metabolic process
B	0009229	biological_process	thiamine diphosphate biosynthetic process
B	0010510	biological_process	regulation of pyruvate decarboxylation to acetyl-CoA
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0030975	molecular_function	thiamine binding
B	0042802	molecular_function	identical protein binding
B	0141200	molecular_function	UTP thiamine diphosphokinase activity