9EMZ
13C/15N-labelled Integral Membrane Enzyme LspA in the Lipid Cubic Phase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006465 | biological_process | signal peptide processing |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004175 | molecular_function | endopeptidase activity |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006465 | biological_process | signal peptide processing |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004175 | molecular_function | endopeptidase activity |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006465 | biological_process | signal peptide processing |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004175 | molecular_function | endopeptidase activity |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006465 | biological_process | signal peptide processing |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00855 |
| Number of Residues | 13 |
| Details | SPASE_II Signal peptidases II signature. VlGGALGNLYDRM |
| Chain | Residue | Details |
| A | VAL105-MET117 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_00161","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26912896","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30272004","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DIR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FMS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 192 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"26912896","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30272004","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DIR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FMS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 168 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"26912896","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30272004","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DIR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FMS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"26912896","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30272004","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DIR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FMS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 52 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"26912896","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DIR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00161","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26912896","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
