9C1B

Crystal structure of GDP-bound human M-RAS protein in crystal form II

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000164	cellular_component	protein phosphatase type 1 complex
A	0000166	molecular_function	nucleotide binding
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0007163	biological_process	establishment or maintenance of cell polarity
A	0007165	biological_process	signal transduction
A	0007265	biological_process	Ras protein signal transduction
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0030036	biological_process	actin cytoskeleton organization
A	0030742	molecular_function	GTP-dependent protein binding
A	0046579	biological_process	positive regulation of Ras protein signal transduction
B	0000164	cellular_component	protein phosphatase type 1 complex
B	0000166	molecular_function	nucleotide binding
B	0003924	molecular_function	GTPase activity
B	0003925	molecular_function	G protein activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0007163	biological_process	establishment or maintenance of cell polarity
B	0007165	biological_process	signal transduction
B	0007265	biological_process	Ras protein signal transduction
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0030036	biological_process	actin cytoskeleton organization
B	0030742	molecular_function	GTP-dependent protein binding
B	0046579	biological_process	positive regulation of Ras protein signal transduction
C	0000164	cellular_component	protein phosphatase type 1 complex
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0003925	molecular_function	G protein activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0007163	biological_process	establishment or maintenance of cell polarity
C	0007165	biological_process	signal transduction
C	0007265	biological_process	Ras protein signal transduction
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0030036	biological_process	actin cytoskeleton organization
C	0030742	molecular_function	GTP-dependent protein binding
C	0046579	biological_process	positive regulation of Ras protein signal transduction
D	0000164	cellular_component	protein phosphatase type 1 complex
D	0000166	molecular_function	nucleotide binding
D	0003924	molecular_function	GTPase activity
D	0003925	molecular_function	G protein activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0007163	biological_process	establishment or maintenance of cell polarity
D	0007165	biological_process	signal transduction
D	0007265	biological_process	Ras protein signal transduction
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0030036	biological_process	actin cytoskeleton organization
D	0030742	molecular_function	GTP-dependent protein binding
D	0046579	biological_process	positive regulation of Ras protein signal transduction

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Motif: {"description":"Effector region"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	76
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35768504","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35830882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36175670","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SD0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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