9C1B
Crystal structure of GDP-bound human M-RAS protein in crystal form II
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000164 | cellular_component | protein phosphatase type 1 complex |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0003925 | molecular_function | G protein activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007165 | biological_process | signal transduction |
| A | 0007265 | biological_process | Ras protein signal transduction |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019003 | molecular_function | GDP binding |
| A | 0030036 | biological_process | actin cytoskeleton organization |
| A | 0030742 | molecular_function | GTP-dependent protein binding |
| A | 1990830 | biological_process | cellular response to leukemia inhibitory factor |
| B | 0000164 | cellular_component | protein phosphatase type 1 complex |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0003925 | molecular_function | G protein activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007165 | biological_process | signal transduction |
| B | 0007265 | biological_process | Ras protein signal transduction |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019003 | molecular_function | GDP binding |
| B | 0030036 | biological_process | actin cytoskeleton organization |
| B | 0030742 | molecular_function | GTP-dependent protein binding |
| B | 1990830 | biological_process | cellular response to leukemia inhibitory factor |
| C | 0000164 | cellular_component | protein phosphatase type 1 complex |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0003925 | molecular_function | G protein activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0007165 | biological_process | signal transduction |
| C | 0007265 | biological_process | Ras protein signal transduction |
| C | 0016020 | cellular_component | membrane |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0019003 | molecular_function | GDP binding |
| C | 0030036 | biological_process | actin cytoskeleton organization |
| C | 0030742 | molecular_function | GTP-dependent protein binding |
| C | 1990830 | biological_process | cellular response to leukemia inhibitory factor |
| D | 0000164 | cellular_component | protein phosphatase type 1 complex |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003924 | molecular_function | GTPase activity |
| D | 0003925 | molecular_function | G protein activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005525 | molecular_function | GTP binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0007165 | biological_process | signal transduction |
| D | 0007265 | biological_process | Ras protein signal transduction |
| D | 0016020 | cellular_component | membrane |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0019003 | molecular_function | GDP binding |
| D | 0030036 | biological_process | actin cytoskeleton organization |
| D | 0030742 | molecular_function | GTP-dependent protein binding |
| D | 1990830 | biological_process | cellular response to leukemia inhibitory factor |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Effector region"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35768504","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35830882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36175670","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SD0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
