9BAQ

CryoEM structure of DIM2-HP1-H3K9me3-DNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0008168	molecular_function	methyltransferase activity
B	0000792	cellular_component	heterochromatin
B	0005634	cellular_component	nucleus
B	0006338	biological_process	chromatin remodeling
C	0000792	cellular_component	heterochromatin
C	0005634	cellular_component	nucleus
C	0006338	biological_process	chromatin remodeling
D	0000786	cellular_component	nucleosome
D	0003677	molecular_function	DNA binding
D	0030527	molecular_function	structural constituent of chromatin
F	0000786	cellular_component	nucleosome
F	0003677	molecular_function	DNA binding
F	0030527	molecular_function	structural constituent of chromatin

Functional Information from PROSITE/UniProt

site_id	PS00094
Number of Residues	13
Details	C5_MTASE_1 C-5 cytosine-specific DNA methylases active site. DfIaaGsPCpGFS

Chain	Residue	Details
A	ASP918-SER930

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
D	LYS14-LEU20

---

site_id	PS00598
Number of Residues	22
Details	CHROMO_1 Chromo domain signature. FlVKWeGYekksdqTWEPedtL

Chain	Residue	Details
B	PHE94-LEU115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N6-methylated lysine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-methylated lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---