8YP6

Cryo-EM map of 30S ribosomal subunit in complex with MetAP1c of Mycobacterium smegmatis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0004239	molecular_function	initiator methionyl aminopeptidase activity
A	0005506	molecular_function	iron ion binding
A	0005829	cellular_component	cytosol
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0016485	biological_process	protein processing
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0050897	molecular_function	cobalt ion binding
A	0070006	molecular_function	metalloaminopeptidase activity
c	0003676	molecular_function	nucleic acid binding
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0006412	biological_process	translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0015935	cellular_component	small ribosomal subunit
d	0019843	molecular_function	rRNA binding
d	0042274	biological_process	ribosomal small subunit biogenesis
d	1990904	cellular_component	ribonucleoprotein complex
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005737	cellular_component	cytoplasm
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0015935	cellular_component	small ribosomal subunit
e	0019843	molecular_function	rRNA binding
e	0042254	biological_process	ribosome biogenesis
e	1990904	cellular_component	ribonucleoprotein complex
f	0003723	molecular_function	RNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0019843	molecular_function	rRNA binding
f	0070181	molecular_function	small ribosomal subunit rRNA binding
f	1990904	cellular_component	ribonucleoprotein complex
g	0000049	molecular_function	tRNA binding
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0015935	cellular_component	small ribosomal subunit
g	0019843	molecular_function	rRNA binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0003723	molecular_function	RNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0019843	molecular_function	rRNA binding
h	1990904	cellular_component	ribonucleoprotein complex
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
j	0000049	molecular_function	tRNA binding
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	1990904	cellular_component	ribonucleoprotein complex
k	0003735	molecular_function	structural constituent of ribosome
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
l	0000049	molecular_function	tRNA binding
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0015935	cellular_component	small ribosomal subunit
l	0019843	molecular_function	rRNA binding
l	1990904	cellular_component	ribonucleoprotein complex
m	0000049	molecular_function	tRNA binding
m	0003676	molecular_function	nucleic acid binding
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0015935	cellular_component	small ribosomal subunit
m	0019843	molecular_function	rRNA binding
m	1990904	cellular_component	ribonucleoprotein complex
n	0003723	molecular_function	RNA binding
n	0003735	molecular_function	structural constituent of ribosome
n	0005737	cellular_component	cytoplasm
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	0008270	molecular_function	zinc ion binding
n	0015935	cellular_component	small ribosomal subunit
n	0019843	molecular_function	rRNA binding
n	0046872	molecular_function	metal ion binding
n	1990904	cellular_component	ribonucleoprotein complex
o	0003723	molecular_function	RNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0019843	molecular_function	rRNA binding
o	0022627	cellular_component	cytosolic small ribosomal subunit
o	1990904	cellular_component	ribonucleoprotein complex
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0019843	molecular_function	rRNA binding
q	0022627	cellular_component	cytosolic small ribosomal subunit
q	1990904	cellular_component	ribonucleoprotein complex
r	0003735	molecular_function	structural constituent of ribosome
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
s	0003723	molecular_function	RNA binding
s	0003735	molecular_function	structural constituent of ribosome
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0015935	cellular_component	small ribosomal subunit
t	0003723	molecular_function	RNA binding
t	0003735	molecular_function	structural constituent of ribosome
t	0005829	cellular_component	cytosol
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0015935	cellular_component	small ribosomal subunit
t	0019843	molecular_function	rRNA binding
t	0070181	molecular_function	small ribosomal subunit rRNA binding
t	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SqLvtqLVnkvlleGKKslaerIVygA

Chain	Residue	Details
g	SER20-ALA46

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GvaIISTSsGLLtdrqAA

Chain	Residue	Details
h	GLY102-ALA119

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrSLqaA.GLeVgtisDvTPqPHN

Chain	Residue	Details
k	ILE106-ASN128

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
l	LYS43-ARG50

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDrVsLmEtRPLS

Chain	Residue	Details
q	GLY71-SER83

---

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.TalLrtYISEr.GKIrarRV

Chain	Residue	Details
r	ILE30-VAL53

---

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. TVDKVDIWGRRrlayeiA

Chain	Residue	Details
f	THR36-ALA53

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. DGRkhvpvfVteamVGhkLGEFapT

Chain	Residue	Details
s	ASP53-THR77

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGpsGQagAlrlAiARAL

Chain	Residue	Details
i	GLY89-LEU107

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. VtrtGAsvvGPVpLPT

Chain	Residue	Details
j	VAL29-THR44

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LteHLkvhKhDhhSrrgLllLvgrrrrLlkY

Chain	Residue	Details
o	LEU39-TYR69

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CnkcgrphsvyrkFGLCRiCLR

Chain	Residue	Details
n	ARG23-ARG45

---

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. SRsefyreGrVplHt..LradIDyglyeakTtfGriG

Chain	Residue	Details
c	SER163-GLY197

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfsFtAlvIVGDgk.GmVGvGygkak.EVpa.AI

Chain	Residue	Details
e	GLY53-ILE85

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRaglArTrrmARqLV

Chain	Residue	Details
d	LEU89-VAL113

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. QGlRHrrGlpVRGQ

Chain	Residue	Details
m	GLN88-GLN101

---

site_id	PS00680
Number of Residues	19
Details	MAP_1 Methionine aminopeptidase subfamily 1 signature. FtGHGIGttfHnglvVl.HY

Chain	Residue	Details
A	PHE202-TYR220

---

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VkIKLTRLGK

Chain	Residue	Details
p	VAL3-LYS12

---

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRRLAYeIA

Chain	Residue	Details
f	GLY44-ALA53

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	Domain: {"description":"KH type-2","evidences":[{"source":"HAMAP-Rule","id":"MF_01309","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	66
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01306","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"HAMAP-Rule","id":"MF_01307","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	70
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	53
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"3-methylthioaspartic acid","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01364","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"35064151","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MSC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MT7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Cross-link: {"description":"Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)","evidences":[{"source":"PubMed","id":"20094657","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35064151","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MSC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MT7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01974","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15882055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20038112","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21465667","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---