8YP6
Cryo-EM map of 30S ribosomal subunit in complex with MetAP1c of Mycobacterium smegmatis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0004239 | molecular_function | initiator methionyl aminopeptidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008235 | molecular_function | metalloexopeptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0046914 | molecular_function | transition metal ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
| d | 0003723 | molecular_function | RNA binding |
| d | 0003735 | molecular_function | structural constituent of ribosome |
| d | 0005840 | cellular_component | ribosome |
| d | 0006412 | biological_process | translation |
| d | 0015935 | cellular_component | small ribosomal subunit |
| d | 0019843 | molecular_function | rRNA binding |
| d | 0042274 | biological_process | ribosomal small subunit biogenesis |
| d | 1990904 | cellular_component | ribonucleoprotein complex |
| e | 0003723 | molecular_function | RNA binding |
| e | 0005737 | cellular_component | cytoplasm |
| e | 0005840 | cellular_component | ribosome |
| e | 0006412 | biological_process | translation |
| e | 0019843 | molecular_function | rRNA binding |
| e | 0042254 | biological_process | ribosome biogenesis |
| e | 1990904 | cellular_component | ribonucleoprotein complex |
| f | 0003723 | molecular_function | RNA binding |
| f | 0003735 | molecular_function | structural constituent of ribosome |
| f | 0005737 | cellular_component | cytoplasm |
| f | 0005840 | cellular_component | ribosome |
| f | 0006412 | biological_process | translation |
| f | 0019843 | molecular_function | rRNA binding |
| f | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
| f | 1990904 | cellular_component | ribonucleoprotein complex |
| g | 0000049 | molecular_function | tRNA binding |
| g | 0003723 | molecular_function | RNA binding |
| g | 0005840 | cellular_component | ribosome |
| g | 0006412 | biological_process | translation |
| g | 0019843 | molecular_function | rRNA binding |
| g | 1990904 | cellular_component | ribonucleoprotein complex |
| h | 0003723 | molecular_function | RNA binding |
| h | 0005737 | cellular_component | cytoplasm |
| h | 0005840 | cellular_component | ribosome |
| h | 0006412 | biological_process | translation |
| h | 0019843 | molecular_function | rRNA binding |
| h | 1990904 | cellular_component | ribonucleoprotein complex |
| j | 0000049 | molecular_function | tRNA binding |
| j | 0005840 | cellular_component | ribosome |
| j | 0006412 | biological_process | translation |
| j | 1990904 | cellular_component | ribonucleoprotein complex |
| l | 0000049 | molecular_function | tRNA binding |
| l | 0003723 | molecular_function | RNA binding |
| l | 0005840 | cellular_component | ribosome |
| l | 0006412 | biological_process | translation |
| l | 0019843 | molecular_function | rRNA binding |
| l | 1990904 | cellular_component | ribonucleoprotein complex |
| m | 0000049 | molecular_function | tRNA binding |
| m | 0003723 | molecular_function | RNA binding |
| m | 0005829 | cellular_component | cytosol |
| m | 0005840 | cellular_component | ribosome |
| m | 0006412 | biological_process | translation |
| m | 0015935 | cellular_component | small ribosomal subunit |
| m | 0019843 | molecular_function | rRNA binding |
| m | 1990904 | cellular_component | ribonucleoprotein complex |
| n | 0003723 | molecular_function | RNA binding |
| n | 0003735 | molecular_function | structural constituent of ribosome |
| n | 0005737 | cellular_component | cytoplasm |
| n | 0005840 | cellular_component | ribosome |
| n | 0006412 | biological_process | translation |
| n | 0008270 | molecular_function | zinc ion binding |
| n | 0015935 | cellular_component | small ribosomal subunit |
| n | 0019843 | molecular_function | rRNA binding |
| n | 0046872 | molecular_function | metal ion binding |
| n | 1990904 | cellular_component | ribonucleoprotein complex |
| o | 0003723 | molecular_function | RNA binding |
| o | 0005737 | cellular_component | cytoplasm |
| o | 0005840 | cellular_component | ribosome |
| o | 0006412 | biological_process | translation |
| o | 0019843 | molecular_function | rRNA binding |
| o | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| o | 1990904 | cellular_component | ribonucleoprotein complex |
| q | 0003723 | molecular_function | RNA binding |
| q | 0003735 | molecular_function | structural constituent of ribosome |
| q | 0005840 | cellular_component | ribosome |
| q | 0006412 | biological_process | translation |
| q | 0019843 | molecular_function | rRNA binding |
| q | 0022627 | cellular_component | cytosolic small ribosomal subunit |
| q | 1990904 | cellular_component | ribonucleoprotein complex |
| t | 0003723 | molecular_function | RNA binding |
| t | 0005829 | cellular_component | cytosol |
| t | 0005840 | cellular_component | ribosome |
| t | 0006412 | biological_process | translation |
| t | 0015935 | cellular_component | small ribosomal subunit |
| t | 0019843 | molecular_function | rRNA binding |
| t | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
| t | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00052 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_S7 Ribosomal protein S7 signature. SqLvtqLVnkvlleGKKslaerIVygA |
| Chain | Residue | Details |
| g | SER20-ALA46 |
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GvaIISTSsGLLtdrqAA |
| Chain | Residue | Details |
| h | GLY102-ALA119 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. IrSLqaA.GLeVgtisDvTPqPHN |
| Chain | Residue | Details |
| k | ILE106-ASN128 |
| site_id | PS00055 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR |
| Chain | Residue | Details |
| l | LYS43-ARG50 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDrVsLmEtRPLS |
| Chain | Residue | Details |
| q | GLY71-SER83 |
| site_id | PS00057 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.TalLrtYISEr.GKIrarRV |
| Chain | Residue | Details |
| r | ILE30-VAL53 |
| site_id | PS00216 |
| Number of Residues | 18 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. TVDKVDIWGRRrlayeiA |
| Chain | Residue | Details |
| f | THR36-ALA53 |
| site_id | PS00323 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S19 Ribosomal protein S19 signature. DGRkhvpvfVteamVGhkLGEFapT |
| Chain | Residue | Details |
| s | ASP53-THR77 |
| site_id | PS00360 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGpsGQagAlrlAiARAL |
| Chain | Residue | Details |
| i | GLY89-LEU107 |
| site_id | PS00361 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_S10 Ribosomal protein S10 signature. VtrtGAsvvGPVpLPT |
| Chain | Residue | Details |
| j | VAL29-THR44 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. LteHLkvhKhDhhSrrgLllLvgrrrrLlkY |
| Chain | Residue | Details |
| o | LEU39-TYR69 |
| site_id | PS00527 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CnkcgrphsvyrkFGLCRiCLR |
| Chain | Residue | Details |
| n | ARG23-ARG45 |
| site_id | PS00548 |
| Number of Residues | 35 |
| Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. SRsefyreGrVplHt..LradIDyglyeakTtfGriG |
| Chain | Residue | Details |
| c | SER163-GLY197 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfsFtAlvIVGDgk.GmVGvGygkak.EVpa.AI |
| Chain | Residue | Details |
| e | GLY53-ILE85 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRaglArTrrmARqLV |
| Chain | Residue | Details |
| d | LEU89-VAL113 |
| site_id | PS00646 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S13_1 Ribosomal protein S13 signature. QGlRHrrGlpVRGQ |
| Chain | Residue | Details |
| m | GLN88-GLN101 |
| site_id | PS00680 |
| Number of Residues | 19 |
| Details | MAP_1 Methionine aminopeptidase subfamily 1 signature. FtGHGIGttfHnglvVl.HY |
| Chain | Residue | Details |
| A | PHE202-TYR220 |
| site_id | PS00732 |
| Number of Residues | 10 |
| Details | RIBOSOMAL_S16 Ribosomal protein S16 signature. VkIKLTRLGK |
| Chain | Residue | Details |
| p | VAL3-LYS12 |
| site_id | PS01048 |
| Number of Residues | 10 |
| Details | RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRRLAYeIA |
| Chain | Residue | Details |
| f | GLY44-ALA53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 68 |
| Details | Domain: {"description":"KH type-2","evidences":[{"source":"HAMAP-Rule","id":"MF_01309","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | Domain: {"description":"S4 RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01306","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 63 |
| Details | Domain: {"description":"S5 DRBM","evidences":[{"source":"HAMAP-Rule","id":"MF_01307","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 70 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 53 |
| Details | Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"3-methylthioaspartic acid","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01364","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)","evidences":[{"source":"PubMed","id":"20094657","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01974","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15882055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20038112","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21465667","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
