8Y8B
Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019062 | biological_process | virion attachment to host cell |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0020002 | cellular_component | host cell plasma membrane |
| A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044173 | cellular_component | host cell endoplasmic reticulum-Golgi intermediate compartment membrane |
| A | 0046718 | biological_process | symbiont entry into host cell |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0055036 | cellular_component | virion membrane |
| A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019062 | biological_process | virion attachment to host cell |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0020002 | cellular_component | host cell plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0044173 | cellular_component | host cell endoplasmic reticulum-Golgi intermediate compartment membrane |
| B | 0046718 | biological_process | symbiont entry into host cell |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| C | VAL291-CYS296 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| C | ASP434-VAL445 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CInpsnw.CDgvsHCpgg.EDEnr...C |
| Chain | Residue | Details |
| C | CYS126-CYS148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| C | CYS296 | |
| C | ILE345 | |
| T | CYS297 | |
| T | ILE346 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| C | GLY441 | |
| T | GLY442 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Cleavage => ECO:0000269|PubMed:11245484 |
| Chain | Residue | Details |
| C | ILE255 | |
| A | ASN335 | |
| A | ASN355 | |
| A | ASN433 | |
| A | ASN454 | |
| A | ASN561 | |
| A | ASN664 | |
| A | ASN684 | |
| A | ASN703 | |
| A | ASN725 | |
| A | ASN771 | |
| T | ILE256 | |
| A | ASN776 | |
| A | ASN793 | |
| A | ASN924 | |
| A | ASN1181 | |
| A | ASN1211 | |
| A | ASN1221 | |
| A | ASN1226 | |
| A | ASN1240 | |
| A | ASN1247 | |
| A | ASN1255 | |
| A | ASN58 | |
| A | ASN1276 | |
| B | ASN19 | |
| B | ASN29 | |
| B | ASN58 | |
| B | ASN114 | |
| B | ASN132 | |
| B | ASN171 | |
| B | ASN188 | |
| B | ASN192 | |
| B | ASN251 | |
| A | ASN114 | |
| B | ASN335 | |
| B | ASN355 | |
| B | ASN433 | |
| B | ASN454 | |
| B | ASN561 | |
| B | ASN664 | |
| B | ASN684 | |
| B | ASN703 | |
| B | ASN725 | |
| B | ASN771 | |
| A | ASN132 | |
| B | ASN776 | |
| B | ASN793 | |
| B | ASN924 | |
| B | ASN1181 | |
| B | ASN1211 | |
| B | ASN1221 | |
| B | ASN1226 | |
| B | ASN1240 | |
| B | ASN1247 | |
| B | ASN1255 | |
| A | ASN171 | |
| B | ASN1276 | |
| A | ASN188 | |
| A | ASN192 | |
| A | ASN251 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| C | ASN213 | |
| C | ASN249 | |
| T | ASN214 | |
| T | ASN250 |
