8X77

Enterovirus proteinase with host factor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0003713	molecular_function	transcription coactivator activity
A	0003779	molecular_function	actin binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0006338	biological_process	chromatin remodeling
A	0008168	molecular_function	methyltransferase activity
A	0016279	molecular_function	protein-lysine N-methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0018021	biological_process	peptidyl-histidine methylation
A	0018023	biological_process	peptidyl-lysine trimethylation
A	0018064	molecular_function	protein-L-histidine N-tele-methyltransferase activity
A	0030047	biological_process	actin modification
A	0032259	biological_process	methylation
A	0042800	molecular_function	histone H3K4 methyltransferase activity
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046975	molecular_function	histone H3K36 methyltransferase activity
A	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
A	0070472	biological_process	regulation of uterine smooth muscle contraction
B	0000785	cellular_component	chromatin
B	0003713	molecular_function	transcription coactivator activity
B	0003779	molecular_function	actin binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006338	biological_process	chromatin remodeling
B	0008168	molecular_function	methyltransferase activity
B	0016279	molecular_function	protein-lysine N-methyltransferase activity
B	0016740	molecular_function	transferase activity
B	0018021	biological_process	peptidyl-histidine methylation
B	0018023	biological_process	peptidyl-lysine trimethylation
B	0018064	molecular_function	protein-L-histidine N-tele-methyltransferase activity
B	0030047	biological_process	actin modification
B	0032259	biological_process	methylation
B	0042800	molecular_function	histone H3K4 methyltransferase activity
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0046975	molecular_function	histone H3K36 methyltransferase activity
B	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
B	0070472	biological_process	regulation of uterine smooth muscle contraction
C	0000166	molecular_function	nucleotide binding
C	0001172	biological_process	RNA-templated transcription
C	0003723	molecular_function	RNA binding
C	0003968	molecular_function	RNA-directed RNA polymerase activity
C	0004386	molecular_function	helicase activity
C	0005524	molecular_function	ATP binding
C	0006508	biological_process	proteolysis
C	0006811	biological_process	monoatomic ion transport
C	0008233	molecular_function	peptidase activity
C	0008234	molecular_function	cysteine-type peptidase activity
C	0008270	molecular_function	zinc ion binding
C	0015267	molecular_function	channel activity
C	0016032	biological_process	viral process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0016787	molecular_function	hydrolase activity
C	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
C	0019028	cellular_component	viral capsid
C	0019062	biological_process	virion attachment to host cell
C	0033644	cellular_component	host cell membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0039520	biological_process	symbiont-mediated activation of host autophagy
C	0039522	biological_process	symbiont-mediated suppression of host mRNA export from nucleus
C	0039618	cellular_component	T=pseudo3 icosahedral viral capsid
C	0039657	biological_process	symbiont-mediated suppression of host gene expression
C	0042025	cellular_component	host cell nucleus
C	0044162	cellular_component	host cell cytoplasmic vesicle membrane
C	0044423	cellular_component	virion component
C	0044694	biological_process	symbiont genome entry into host cell via pore formation in plasma membrane
C	0046718	biological_process	symbiont entry into host cell
C	0046872	molecular_function	metal ion binding
C	0052031	biological_process	symbiont-mediated perturbation of host defense response
C	0052170	biological_process	symbiont-mediated suppression of host innate immune response
C	0075509	biological_process	endocytosis involved in viral entry into host cell
D	0000785	cellular_component	chromatin
D	0003713	molecular_function	transcription coactivator activity
D	0003779	molecular_function	actin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0006338	biological_process	chromatin remodeling
D	0008168	molecular_function	methyltransferase activity
D	0016279	molecular_function	protein-lysine N-methyltransferase activity
D	0016740	molecular_function	transferase activity
D	0018021	biological_process	peptidyl-histidine methylation
D	0018023	biological_process	peptidyl-lysine trimethylation
D	0018064	molecular_function	protein-L-histidine N-tele-methyltransferase activity
D	0030047	biological_process	actin modification
D	0032259	biological_process	methylation
D	0042800	molecular_function	histone H3K4 methyltransferase activity
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0046975	molecular_function	histone H3K36 methyltransferase activity
D	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
D	0070472	biological_process	regulation of uterine smooth muscle contraction
E	0000166	molecular_function	nucleotide binding
E	0001172	biological_process	RNA-templated transcription
E	0003723	molecular_function	RNA binding
E	0003968	molecular_function	RNA-directed RNA polymerase activity
E	0004386	molecular_function	helicase activity
E	0005524	molecular_function	ATP binding
E	0006508	biological_process	proteolysis
E	0006811	biological_process	monoatomic ion transport
E	0008233	molecular_function	peptidase activity
E	0008234	molecular_function	cysteine-type peptidase activity
E	0008270	molecular_function	zinc ion binding
E	0015267	molecular_function	channel activity
E	0016032	biological_process	viral process
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0016787	molecular_function	hydrolase activity
E	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
E	0019028	cellular_component	viral capsid
E	0019062	biological_process	virion attachment to host cell
E	0033644	cellular_component	host cell membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0039520	biological_process	symbiont-mediated activation of host autophagy
E	0039522	biological_process	symbiont-mediated suppression of host mRNA export from nucleus
E	0039618	cellular_component	T=pseudo3 icosahedral viral capsid
E	0039657	biological_process	symbiont-mediated suppression of host gene expression
E	0042025	cellular_component	host cell nucleus
E	0044162	cellular_component	host cell cytoplasmic vesicle membrane
E	0044423	cellular_component	virion component
E	0044694	biological_process	symbiont genome entry into host cell via pore formation in plasma membrane
E	0046718	biological_process	symbiont entry into host cell
E	0046872	molecular_function	metal ion binding
E	0052031	biological_process	symbiont-mediated perturbation of host defense response
E	0052170	biological_process	symbiont-mediated suppression of host innate immune response
E	0075509	biological_process	endocytosis involved in viral entry into host cell
F	0000166	molecular_function	nucleotide binding
F	0001172	biological_process	RNA-templated transcription
F	0003723	molecular_function	RNA binding
F	0003968	molecular_function	RNA-directed RNA polymerase activity
F	0004386	molecular_function	helicase activity
F	0005524	molecular_function	ATP binding
F	0006508	biological_process	proteolysis
F	0006811	biological_process	monoatomic ion transport
F	0008233	molecular_function	peptidase activity
F	0008234	molecular_function	cysteine-type peptidase activity
F	0008270	molecular_function	zinc ion binding
F	0015267	molecular_function	channel activity
F	0016032	biological_process	viral process
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0016787	molecular_function	hydrolase activity
F	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
F	0019028	cellular_component	viral capsid
F	0019062	biological_process	virion attachment to host cell
F	0033644	cellular_component	host cell membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0039520	biological_process	symbiont-mediated activation of host autophagy
F	0039522	biological_process	symbiont-mediated suppression of host mRNA export from nucleus
F	0039618	cellular_component	T=pseudo3 icosahedral viral capsid
F	0039657	biological_process	symbiont-mediated suppression of host gene expression
F	0042025	cellular_component	host cell nucleus
F	0044162	cellular_component	host cell cytoplasmic vesicle membrane
F	0044423	cellular_component	virion component
F	0044694	biological_process	symbiont genome entry into host cell via pore formation in plasma membrane
F	0046718	biological_process	symbiont entry into host cell
F	0046872	molecular_function	metal ion binding
F	0052031	biological_process	symbiont-mediated perturbation of host defense response
F	0052170	biological_process	symbiont-mediated suppression of host innate immune response
F	0075509	biological_process	endocytosis involved in viral entry into host cell
G	0000785	cellular_component	chromatin
G	0003713	molecular_function	transcription coactivator activity
G	0003779	molecular_function	actin binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0006338	biological_process	chromatin remodeling
G	0008168	molecular_function	methyltransferase activity
G	0016279	molecular_function	protein-lysine N-methyltransferase activity
G	0016740	molecular_function	transferase activity
G	0018021	biological_process	peptidyl-histidine methylation
G	0018023	biological_process	peptidyl-lysine trimethylation
G	0018064	molecular_function	protein-L-histidine N-tele-methyltransferase activity
G	0030047	biological_process	actin modification
G	0032259	biological_process	methylation
G	0042800	molecular_function	histone H3K4 methyltransferase activity
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0045944	biological_process	positive regulation of transcription by RNA polymerase II
G	0046975	molecular_function	histone H3K36 methyltransferase activity
G	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
G	0070472	biological_process	regulation of uterine smooth muscle contraction
H	0000166	molecular_function	nucleotide binding
H	0001172	biological_process	RNA-templated transcription
H	0003723	molecular_function	RNA binding
H	0003968	molecular_function	RNA-directed RNA polymerase activity
H	0004386	molecular_function	helicase activity
H	0005524	molecular_function	ATP binding
H	0006508	biological_process	proteolysis
H	0006811	biological_process	monoatomic ion transport
H	0008233	molecular_function	peptidase activity
H	0008234	molecular_function	cysteine-type peptidase activity
H	0008270	molecular_function	zinc ion binding
H	0015267	molecular_function	channel activity
H	0016032	biological_process	viral process
H	0016740	molecular_function	transferase activity
H	0016779	molecular_function	nucleotidyltransferase activity
H	0016787	molecular_function	hydrolase activity
H	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
H	0019028	cellular_component	viral capsid
H	0019062	biological_process	virion attachment to host cell
H	0033644	cellular_component	host cell membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0039520	biological_process	symbiont-mediated activation of host autophagy
H	0039522	biological_process	symbiont-mediated suppression of host mRNA export from nucleus
H	0039618	cellular_component	T=pseudo3 icosahedral viral capsid
H	0039657	biological_process	symbiont-mediated suppression of host gene expression
H	0042025	cellular_component	host cell nucleus
H	0044162	cellular_component	host cell cytoplasmic vesicle membrane
H	0044423	cellular_component	virion component
H	0044694	biological_process	symbiont genome entry into host cell via pore formation in plasma membrane
H	0046718	biological_process	symbiont entry into host cell
H	0046872	molecular_function	metal ion binding
H	0052031	biological_process	symbiont-mediated perturbation of host defense response
H	0052170	biological_process	symbiont-mediated suppression of host innate immune response
H	0075509	biological_process	endocytosis involved in viral entry into host cell

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	880
Details	Domain: {"description":"SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30626964","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30785395","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31388018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31911441","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31993215","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32503840","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2011","submissionDatabase":"PDB data bank","title":"Crystal structure of human SET domain-containing protein 3.","authors":["Zeng H.","Dong A.","Walker J.R.","Loppnau P.","Bountra C.","Weigelt J.","Arrowsmith C.H.","Edwards A.M.","Min J.","Wu H."]}},{"source":"PDB","id":"3SMT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ICT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ICV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JAT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MBL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OX2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OX3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OX4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OX5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6V62","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6V63","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WK1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WK2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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