6OX0
SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor
Summary for 6OX0
Entry DOI | 10.2210/pdb6ox0/pdb |
Descriptor | Actin Peptide, Histone-lysine N-methyltransferase setd3, SINEFUNGIN, ... (5 entities in total) |
Functional Keywords | transferase, transferase-structural protein complex, transferase/structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 141645.78 |
Authors | Horton, J.R.,Dai, S.,Cheng, X. (deposition date: 2019-05-13, release date: 2019-08-21, Last modification date: 2023-10-11) |
Primary citation | Dai, S.,Horton, J.R.,Woodcock, C.B.,Wilkinson, A.W.,Zhang, X.,Gozani, O.,Cheng, X. Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10:3541-3541, 2019 Cited by PubMed: 31388018DOI: 10.1038/s41467-019-11554-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.755 Å) |
Structure validation
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