8WV1

Ambient Temperature Structure of 50S Ribosomal Subunit from Thermus Thermophilus

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003735	molecular_function	structural constituent of ribosome
0	0006412	biological_process	translation
0	0015934	cellular_component	large ribosomal subunit
13	0003735	molecular_function	structural constituent of ribosome
13	0005737	cellular_component	cytoplasm
13	0005840	cellular_component	ribosome
13	0006412	biological_process	translation
2	0003735	molecular_function	structural constituent of ribosome
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
3	0003735	molecular_function	structural constituent of ribosome
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0015934	cellular_component	large ribosomal subunit
3	0022625	cellular_component	cytosolic large ribosomal subunit
4	0003735	molecular_function	structural constituent of ribosome
4	0005737	cellular_component	cytoplasm
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
5	0003735	molecular_function	structural constituent of ribosome
5	0006412	biological_process	translation
5	0015934	cellular_component	large ribosomal subunit
6	0003735	molecular_function	structural constituent of ribosome
6	0005737	cellular_component	cytoplasm
6	0005840	cellular_component	ribosome
6	0006412	biological_process	translation
7	0003735	molecular_function	structural constituent of ribosome
7	0005840	cellular_component	ribosome
7	0006412	biological_process	translation
8	0003735	molecular_function	structural constituent of ribosome
8	0005840	cellular_component	ribosome
8	0006412	biological_process	translation
8	0015934	cellular_component	large ribosomal subunit
8	0022625	cellular_component	cytosolic large ribosomal subunit
9	0003735	molecular_function	structural constituent of ribosome
9	0005737	cellular_component	cytoplasm
9	0005840	cellular_component	ribosome
9	0006412	biological_process	translation
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0015934	cellular_component	large ribosomal subunit
c	0016740	molecular_function	transferase activity
c	0019843	molecular_function	rRNA binding
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0015934	cellular_component	large ribosomal subunit
C	0016740	molecular_function	transferase activity
C	0019843	molecular_function	rRNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0019843	molecular_function	rRNA binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0019843	molecular_function	rRNA binding
D	0022625	cellular_component	cytosolic large ribosomal subunit
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0019843	molecular_function	rRNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
f	0000049	molecular_function	tRNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0019843	molecular_function	rRNA binding
F	0000049	molecular_function	tRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
G	0022625	cellular_component	cytosolic large ribosomal subunit
h	0003735	molecular_function	structural constituent of ribosome
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0019843	molecular_function	rRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
i	0003729	molecular_function	mRNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0017148	biological_process	negative regulation of translation
i	0022625	cellular_component	cytosolic large ribosomal subunit
I	0003729	molecular_function	mRNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0017148	biological_process	negative regulation of translation
I	0022625	cellular_component	cytosolic large ribosomal subunit
j	0003735	molecular_function	structural constituent of ribosome
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	0015934	cellular_component	large ribosomal subunit
j	0019843	molecular_function	rRNA binding
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0070180	molecular_function	large ribosomal subunit rRNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015934	cellular_component	large ribosomal subunit
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	0070180	molecular_function	large ribosomal subunit rRNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0015934	cellular_component	large ribosomal subunit
k	0019843	molecular_function	rRNA binding
k	0022625	cellular_component	cytosolic large ribosomal subunit
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0015934	cellular_component	large ribosomal subunit
K	0019843	molecular_function	rRNA binding
K	0022625	cellular_component	cytosolic large ribosomal subunit
l	0003735	molecular_function	structural constituent of ribosome
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0019843	molecular_function	rRNA binding
l	0022625	cellular_component	cytosolic large ribosomal subunit
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0019843	molecular_function	rRNA binding
L	0022625	cellular_component	cytosolic large ribosomal subunit
m	0003735	molecular_function	structural constituent of ribosome
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0015934	cellular_component	large ribosomal subunit
m	0022625	cellular_component	cytosolic large ribosomal subunit
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015934	cellular_component	large ribosomal subunit
M	0022625	cellular_component	cytosolic large ribosomal subunit
n	0003735	molecular_function	structural constituent of ribosome
n	0005737	cellular_component	cytoplasm
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	0008097	molecular_function	5S rRNA binding
n	0019843	molecular_function	rRNA binding
n	0022625	cellular_component	cytosolic large ribosomal subunit
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0008097	molecular_function	5S rRNA binding
N	0019843	molecular_function	rRNA binding
N	0022625	cellular_component	cytosolic large ribosomal subunit
o	0003735	molecular_function	structural constituent of ribosome
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0022625	cellular_component	cytosolic large ribosomal subunit
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0022625	cellular_component	cytosolic large ribosomal subunit
p	0000027	biological_process	ribosomal large subunit assembly
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0019843	molecular_function	rRNA binding
P	0000027	biological_process	ribosomal large subunit assembly
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0019843	molecular_function	rRNA binding
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005737	cellular_component	cytoplasm
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0019843	molecular_function	rRNA binding
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0015934	cellular_component	large ribosomal subunit
r	0019843	molecular_function	rRNA binding
r	0022625	cellular_component	cytosolic large ribosomal subunit
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0015934	cellular_component	large ribosomal subunit
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
s	0003735	molecular_function	structural constituent of ribosome
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0019843	molecular_function	rRNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0019843	molecular_function	rRNA binding
t	0003723	molecular_function	RNA binding
t	0003735	molecular_function	structural constituent of ribosome
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0019843	molecular_function	rRNA binding
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
u	0003723	molecular_function	RNA binding
u	0003735	molecular_function	structural constituent of ribosome
u	0005840	cellular_component	ribosome
u	0006412	biological_process	translation
u	0008097	molecular_function	5S rRNA binding
u	0022625	cellular_component	cytosolic large ribosomal subunit
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0008097	molecular_function	5S rRNA binding
U	0022625	cellular_component	cytosolic large ribosomal subunit
v	0003735	molecular_function	structural constituent of ribosome
v	0005840	cellular_component	ribosome
v	0006412	biological_process	translation
v	0022625	cellular_component	cytosolic large ribosomal subunit
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
w	0003735	molecular_function	structural constituent of ribosome
w	0005840	cellular_component	ribosome
w	0006412	biological_process	translation
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
x	0003735	molecular_function	structural constituent of ribosome
x	0005840	cellular_component	ribosome
x	0006412	biological_process	translation
x	0022625	cellular_component	cytosolic large ribosomal subunit
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0022625	cellular_component	cytosolic large ribosomal subunit
y	0003735	molecular_function	structural constituent of ribosome
y	0006412	biological_process	translation
y	0015934	cellular_component	large ribosomal subunit
y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0003735	molecular_function	structural constituent of ribosome
Y	0006412	biological_process	translation
Y	0015934	cellular_component	large ribosomal subunit
Y	0022625	cellular_component	cytosolic large ribosomal subunit
z	0003735	molecular_function	structural constituent of ribosome
z	0005840	cellular_component	ribosome
z	0006412	biological_process	translation
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkeikrp.DGsairFddNaaVI

Chain	Residue	Details
J	ALA60-ILE86

---

site_id	PS00196
Number of Residues	16
Details	COPPER_BLUE Type-1 copper (blue) proteins signature. GrvY.VICenPkHkqr.Q

Chain	Residue	Details
4	GLY21-GLN36

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LalITGQkpAvTrAKkS

Chain	Residue	Details
F	LEU60-SER76

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KrvLpRArGRadiikkrtSHITViL

Chain	Residue	Details
R	LYS83-LEU107

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PhvRGAAmNPvD

Chain	Residue	Details
C	PRO219-ASP230

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FkpgervDvtGtSkGRGfaGvmkR

Chain	Residue	Details
D	PHE96-ARG119

---

site_id	PS00475
Number of Residues	30
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGeGeAkp...LkVvahaFSksAlekLkaaG

Chain	Residue	Details
K	LYS113-GLY142

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QNHKIRdLKRQIARL

Chain	Residue	Details
x	GLN46-LEU60

---

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YaTeKNkrntPnkLElrKYC

Chain	Residue	Details
13	TYR21-CYS40

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. ALkaLgLrRlqQeRvledtpairgNVekVahLV

Chain	Residue	Details
y	ALA22-VAL54

---

site_id	PS00651
Number of Residues	28
Details	RIBOSOMAL_L9 Ribosomal protein L9 signature. GdvGqvvdVkpGYarNYLlprglAvlaT

Chain	Residue	Details
H	GLY13-THR40

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRrlfkrLkVYaG

Chain	Residue	Details
I	VAL103-GLY125

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTWQpnrrkRakth.GFraR

Chain	Residue	Details
2	LYS2-ARG21

---

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CdkCkvIrRhgrVyViCenp.KHkQrQ

Chain	Residue	Details
4	CYS11-GLN36

---

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GnILvRQRGtrfkpG

Chain	Residue	Details
v	GLY34-GLY48

---

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHkGAkKRVkitasgkvvamktgk.RH

Chain	Residue	Details
3	LYS5-HIS31

---

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRrLWIVRINaacR

Chain	Residue	Details
P	LYS54-ARG70

---

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. IvQrGRAR.RAKLYFIR

Chain	Residue	Details
O	ILE88-ARG103

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVlVAsGkyKGrv.GkV

Chain	Residue	Details
T	GLY10-VAL27

---

site_id	PS01143
Number of Residues	22
Details	RIBOSOMAL_L31 Ribosomal protein L31 signature. EVcskcHPFYTgqqrfvdte....GR

Chain	Residue	Details
z	GLU34-ARG55

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	224
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	56
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00501","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P80256","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---