8VY2

Structure of mCELSR1 extracellular region containing CADH9-GAIN domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0005509	molecular_function	calcium ion binding
A	0005886	cellular_component	plasma membrane
A	0007155	biological_process	cell adhesion
A	0007156	biological_process	homophilic cell-cell adhesion
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CvNrwntYlCeC

Chain	Residue	Details
A	CYS1679-CYS1690
A	CYS1902-CYS1913

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CrCppGftGDyC

Chain	Residue	Details
A	CYS1364-CYS1375
A	CYS1402-CYS1413
A	CYS1688-CYS1699
A	CYS1911-CYS1922
A	CYS1949-CYS1960
A	CYS2037-CYS2048

---

site_id	PS00232
Number of Residues	11
Details	CADHERIN_1 Cadherin domain signature. VtVsDtNDHsP

Chain	Residue	Details
A	VAL356-PRO366
A	ILE462-PRO472
A	VAL568-PRO578
A	ILE690-PRO700
A	ILE895-PRO905
A	VAL1002-PRO1012
A	ILE1104-PRO1114

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CrCppGFtgdy....C

Chain	Residue	Details
A	CYS1364-CYS1375
A	CYS1911-CYS1926

---

site_id	PS01248
Number of Residues	34
Details	EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Ca.CkpgviGrqCnrCdnp.Faevtslgceviyng.C

Chain	Residue	Details
A	CYS2037-CYS2070

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	118
Details	Domain: {"description":"Cadherin 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	58
Details	Domain: {"description":"EGF-like 1; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	Domain: {"description":"EGF-like 2; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	38
Details	Domain: {"description":"EGF-like 3; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	204
Details	Domain: {"description":"Laminin G-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00122","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	36
Details	Domain: {"description":"EGF-like 4; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	181
Details	Domain: {"description":"Laminin G-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00122","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	35
Details	Domain: {"description":"EGF-like 5; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	38
Details	Domain: {"description":"EGF-like 6; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	32
Details	Domain: {"description":"EGF-like 7; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	35
Details	Domain: {"description":"EGF-like 8; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	47
Details	Domain: {"description":"Laminin EGF-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"(3R)-3-hydroxyasparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"(3R)-3-hydroxyaspartate","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	18
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---