8UVM
SARS-CoV-2 papain-like protease (PLpro) complex with covalent inhibitor Jun11313
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 148 |
| Details | ZN_FING: C4-type => ECO:0000255|PROSITE-ProRule:PRU00444 |
| Chain | Residue | Details |
| A | CYS189-CYS226 | |
| B | CYS189-CYS226 | |
| C | CYS189-CYS226 | |
| D | CYS189-CYS226 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444, ECO:0000269|PubMed:32726803 |
| Chain | Residue | Details |
| A | CYS111 | |
| B | CYS111 | |
| C | CYS111 | |
| D | CYS111 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444 |
| Chain | Residue | Details |
| A | HIS272 | |
| A | ASP286 | |
| B | HIS272 | |
| B | ASP286 | |
| C | HIS272 | |
| C | ASP286 | |
| D | HIS272 | |
| D | ASP286 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00444 |
| Chain | Residue | Details |
| A | CYS189 | |
| C | CYS192 | |
| C | CYS224 | |
| C | CYS226 | |
| D | CYS189 | |
| D | CYS192 | |
| D | CYS224 | |
| D | CYS226 | |
| A | CYS192 | |
| A | CYS224 | |
| A | CYS226 | |
| B | CYS189 | |
| B | CYS192 | |
| B | CYS224 | |
| B | CYS226 | |
| C | CYS189 |
