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8USR

IL17A homodimer complexed to Compound 23

Functional Information from GO Data
ChainGOidnamespacecontents
A0002225biological_processpositive regulation of antimicrobial peptide production
A0002250biological_processadaptive immune response
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006915biological_processapoptotic process
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007219biological_processNotch signaling pathway
A0007267biological_processcell-cell signaling
A0008219biological_processcell death
A0009611biological_processresponse to wounding
A0009897cellular_componentexternal side of plasma membrane
A0010467biological_processgene expression
A0030216biological_processkeratinocyte differentiation
A0032731biological_processpositive regulation of interleukin-1 beta production
A0032735biological_processpositive regulation of interleukin-12 production
A0032739biological_processpositive regulation of interleukin-16 production
A0032747biological_processpositive regulation of interleukin-23 production
A0032755biological_processpositive regulation of interleukin-6 production
A0032760biological_processpositive regulation of tumor necrosis factor production
A0038173biological_processinterleukin-17A-mediated signaling pathway
A0042803molecular_functionprotein homodimerization activity
A0043616biological_processkeratinocyte proliferation
A0045087biological_processinnate immune response
A0045672biological_processpositive regulation of osteoclast differentiation
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046982molecular_functionprotein heterodimerization activity
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0050832biological_processdefense response to fungus
A0060729biological_processintestinal epithelial structure maintenance
A0071347biological_processcellular response to interleukin-1
A0072537biological_processfibroblast activation
A0097400biological_processinterleukin-17-mediated signaling pathway
A0097530biological_processgranulocyte migration
A0106015biological_processnegative regulation of inflammatory response to wounding
A1900017biological_processpositive regulation of cytokine production involved in inflammatory response
A1903348biological_processpositive regulation of bicellular tight junction assembly
A2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
B0002225biological_processpositive regulation of antimicrobial peptide production
B0002250biological_processadaptive immune response
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006915biological_processapoptotic process
B0006954biological_processinflammatory response
B0006955biological_processimmune response
B0007219biological_processNotch signaling pathway
B0007267biological_processcell-cell signaling
B0008219biological_processcell death
B0009611biological_processresponse to wounding
B0009897cellular_componentexternal side of plasma membrane
B0010467biological_processgene expression
B0030216biological_processkeratinocyte differentiation
B0032731biological_processpositive regulation of interleukin-1 beta production
B0032735biological_processpositive regulation of interleukin-12 production
B0032739biological_processpositive regulation of interleukin-16 production
B0032747biological_processpositive regulation of interleukin-23 production
B0032755biological_processpositive regulation of interleukin-6 production
B0032760biological_processpositive regulation of tumor necrosis factor production
B0038173biological_processinterleukin-17A-mediated signaling pathway
B0042803molecular_functionprotein homodimerization activity
B0043616biological_processkeratinocyte proliferation
B0045087biological_processinnate immune response
B0045672biological_processpositive regulation of osteoclast differentiation
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0046982molecular_functionprotein heterodimerization activity
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0050832biological_processdefense response to fungus
B0060729biological_processintestinal epithelial structure maintenance
B0071347biological_processcellular response to interleukin-1
B0072537biological_processfibroblast activation
B0097400biological_processinterleukin-17-mediated signaling pathway
B0097530biological_processgranulocyte migration
B0106015biological_processnegative regulation of inflammatory response to wounding
B1900017biological_processpositive regulation of cytokine production involved in inflammatory response
B1903348biological_processpositive regulation of bicellular tight junction assembly
B2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
C0002225biological_processpositive regulation of antimicrobial peptide production
C0002250biological_processadaptive immune response
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0006915biological_processapoptotic process
C0006954biological_processinflammatory response
C0006955biological_processimmune response
C0007219biological_processNotch signaling pathway
C0007267biological_processcell-cell signaling
C0008219biological_processcell death
C0009611biological_processresponse to wounding
C0009897cellular_componentexternal side of plasma membrane
C0010467biological_processgene expression
C0030216biological_processkeratinocyte differentiation
C0032731biological_processpositive regulation of interleukin-1 beta production
C0032735biological_processpositive regulation of interleukin-12 production
C0032739biological_processpositive regulation of interleukin-16 production
C0032747biological_processpositive regulation of interleukin-23 production
C0032755biological_processpositive regulation of interleukin-6 production
C0032760biological_processpositive regulation of tumor necrosis factor production
C0038173biological_processinterleukin-17A-mediated signaling pathway
C0042803molecular_functionprotein homodimerization activity
C0043616biological_processkeratinocyte proliferation
C0045087biological_processinnate immune response
C0045672biological_processpositive regulation of osteoclast differentiation
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0046982molecular_functionprotein heterodimerization activity
C0050829biological_processdefense response to Gram-negative bacterium
C0050830biological_processdefense response to Gram-positive bacterium
C0050832biological_processdefense response to fungus
C0060729biological_processintestinal epithelial structure maintenance
C0071347biological_processcellular response to interleukin-1
C0072537biological_processfibroblast activation
C0097400biological_processinterleukin-17-mediated signaling pathway
C0097530biological_processgranulocyte migration
C0106015biological_processnegative regulation of inflammatory response to wounding
C1900017biological_processpositive regulation of cytokine production involved in inflammatory response
C1903348biological_processpositive regulation of bicellular tight junction assembly
C2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
D0002225biological_processpositive regulation of antimicrobial peptide production
D0002250biological_processadaptive immune response
D0005125molecular_functioncytokine activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0006915biological_processapoptotic process
D0006954biological_processinflammatory response
D0006955biological_processimmune response
D0007219biological_processNotch signaling pathway
D0007267biological_processcell-cell signaling
D0008219biological_processcell death
D0009611biological_processresponse to wounding
D0009897cellular_componentexternal side of plasma membrane
D0010467biological_processgene expression
D0030216biological_processkeratinocyte differentiation
D0032731biological_processpositive regulation of interleukin-1 beta production
D0032735biological_processpositive regulation of interleukin-12 production
D0032739biological_processpositive regulation of interleukin-16 production
D0032747biological_processpositive regulation of interleukin-23 production
D0032755biological_processpositive regulation of interleukin-6 production
D0032760biological_processpositive regulation of tumor necrosis factor production
D0038173biological_processinterleukin-17A-mediated signaling pathway
D0042803molecular_functionprotein homodimerization activity
D0043616biological_processkeratinocyte proliferation
D0045087biological_processinnate immune response
D0045672biological_processpositive regulation of osteoclast differentiation
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D0046982molecular_functionprotein heterodimerization activity
D0050829biological_processdefense response to Gram-negative bacterium
D0050830biological_processdefense response to Gram-positive bacterium
D0050832biological_processdefense response to fungus
D0060729biological_processintestinal epithelial structure maintenance
D0071347biological_processcellular response to interleukin-1
D0072537biological_processfibroblast activation
D0097400biological_processinterleukin-17-mediated signaling pathway
D0097530biological_processgranulocyte migration
D0106015biological_processnegative regulation of inflammatory response to wounding
D1900017biological_processpositive regulation of cytokine production involved in inflammatory response
D1903348biological_processpositive regulation of bicellular tight junction assembly
D2000340biological_processpositive regulation of chemokine (C-X-C motif) ligand 1 production
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN68
BASN68
CASN68
DASN68

226707

PDB entries from 2024-10-30

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