8T60
CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015293 | molecular_function | symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR194-HIS200 | |
| L | TYR192-HIS198 |
| site_id | PS00872 |
| Number of Residues | 26 |
| Details | NA_GALACTOSIDE_SYMP Sodium:galactoside symporter family signature. DpimGwivNatrsrw..GKFKPWILiGT |
| Chain | Residue | Details |
| A | ASP59-THR84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 274 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34341464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7L16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7L17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"34341464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7L16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7L17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34341464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7L16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7L17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34341464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7L17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
