8SRY

Crystal structure of BAK-BAX heterodimer with C12E8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
B	0042981	biological_process	regulation of apoptotic process
C	0042981	biological_process	regulation of apoptotic process
D	0042981	biological_process	regulation of apoptotic process

Functional Information from PROSITE/UniProt

site_id	PS01080
Number of Residues	20
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. MFsDGnfNWGRVVALFyFAS

Chain	Residue	Details
B	MET99-SER118
A	LEU118-TYR136

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. LsesLKrIGDELDSN

Chain	Residue	Details
B	LEU59-ASN73
A	VAL74-ARG88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Motif: {"description":"BH3"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	78
Details	Motif: {"description":"BH1"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Motif: {"description":"BH3","evidences":[{"source":"PubMed","id":"8521816","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36361894","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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