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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8RBZ

Structure of Integrator-PP2A-SOSS-CTD post-termination complex

Functional Information from GO Data
ChainGOidnamespacecontents
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005654cellular_componentnucleoplasm
a0016020cellular_componentmembrane
a0016180biological_processsnRNA processing
a0031965cellular_componentnuclear membrane
a0032039cellular_componentintegrator complex
a0034243biological_processregulation of transcription elongation by RNA polymerase II
a0034474biological_processU2 snRNA 3'-end processing
a0160232cellular_componentINTAC complex
a0160240biological_processRNA polymerase II transcription initiation surveillance
b0016180biological_processsnRNA processing
b0032039cellular_componentintegrator complex
B0000724biological_processdouble-strand break repair via homologous recombination
B0000781cellular_componentchromosome, telomeric region
B0003677molecular_functionDNA binding
B0003697molecular_functionsingle-stranded DNA binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0006281biological_processDNA repair
B0006974biological_processDNA damage response
B0010212biological_processresponse to ionizing radiation
B0035861cellular_componentsite of double-strand break
B0044818biological_processmitotic G2/M transition checkpoint
B0061730molecular_functionC-rich strand telomeric DNA binding
B0070182molecular_functionDNA polymerase binding
B0070200biological_processestablishment of protein localization to telomere
B0070876cellular_componentSOSS complex
B0098505molecular_functionG-rich strand telomeric DNA binding
B1904355biological_processpositive regulation of telomere capping
c0000724biological_processdouble-strand break repair via homologous recombination
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005654cellular_componentnucleoplasm
c0005737cellular_componentcytoplasm
c0006281biological_processDNA repair
c0006974biological_processDNA damage response
c0010212biological_processresponse to ionizing radiation
c0016180biological_processsnRNA processing
c0032039cellular_componentintegrator complex
c0034243biological_processregulation of transcription elongation by RNA polymerase II
c0035861cellular_componentsite of double-strand break
c0044818biological_processmitotic G2/M transition checkpoint
c0070876cellular_componentSOSS complex
c0160232cellular_componentINTAC complex
c0160240biological_processRNA polymerase II transcription initiation surveillance
C0000724biological_processdouble-strand break repair via homologous recombination
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0006281biological_processDNA repair
C0006974biological_processDNA damage response
C0010212biological_processresponse to ionizing radiation
C0035861cellular_componentsite of double-strand break
C0044818biological_processmitotic G2/M transition checkpoint
C0070876cellular_componentSOSS complex
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0005730cellular_componentnucleolus
d0005737cellular_componentcytoplasm
d0016180biological_processsnRNA processing
d0030674molecular_functionprotein-macromolecule adaptor activity
d0032039cellular_componentintegrator complex
d0034243biological_processregulation of transcription elongation by RNA polymerase II
d0160232cellular_componentINTAC complex
d0160240biological_processRNA polymerase II transcription initiation surveillance
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005737cellular_componentcytoplasm
e0005829cellular_componentcytosol
e0016020cellular_componentmembrane
e0016180biological_processsnRNA processing
e0031965cellular_componentnuclear membrane
e0032039cellular_componentintegrator complex
e0034243biological_processregulation of transcription elongation by RNA polymerase II
e0034472biological_processsnRNA 3'-end processing
e0160232cellular_componentINTAC complex
e0160240biological_processRNA polymerase II transcription initiation surveillance
f0000785cellular_componentchromatin
f0004888molecular_functiontransmembrane signaling receptor activity
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005654cellular_componentnucleoplasm
f0005694cellular_componentchromosome
f0016180biological_processsnRNA processing
f0030674molecular_functionprotein-macromolecule adaptor activity
f0032039cellular_componentintegrator complex
f0034243biological_processregulation of transcription elongation by RNA polymerase II
f0034472biological_processsnRNA 3'-end processing
f0071168biological_processprotein localization to chromatin
f0160232cellular_componentINTAC complex
f0160240biological_processRNA polymerase II transcription initiation surveillance
g0000077biological_processDNA damage checkpoint signaling
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005654cellular_componentnucleoplasm
g0005694cellular_componentchromosome
g0005737cellular_componentcytoplasm
g0006974biological_processDNA damage response
g0016180biological_processsnRNA processing
g0016604cellular_componentnuclear body
g0032039cellular_componentintegrator complex
g0034243biological_processregulation of transcription elongation by RNA polymerase II
g0034472biological_processsnRNA 3'-end processing
g0071479biological_processcellular response to ionizing radiation
g0160232cellular_componentINTAC complex
g0160240biological_processRNA polymerase II transcription initiation surveillance
h0000785cellular_componentchromatin
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005654cellular_componentnucleoplasm
h0005694cellular_componentchromosome
h0016180biological_processsnRNA processing
h0032039cellular_componentintegrator complex
h0034243biological_processregulation of transcription elongation by RNA polymerase II
h0034472biological_processsnRNA 3'-end processing
h0071168biological_processprotein localization to chromatin
h0160232cellular_componentINTAC complex
h0160240biological_processRNA polymerase II transcription initiation surveillance
i0005515molecular_functionprotein binding
i0005634cellular_componentnucleus
i0005654cellular_componentnucleoplasm
i0005737cellular_componentcytoplasm
i0005829cellular_componentcytosol
i0016180biological_processsnRNA processing
i0030512biological_processnegative regulation of transforming growth factor beta receptor signaling pathway
i0032039cellular_componentintegrator complex
i0034243biological_processregulation of transcription elongation by RNA polymerase II
i0034472biological_processsnRNA 3'-end processing
i0090101biological_processnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
i0090287biological_processregulation of cellular response to growth factor stimulus
i0160232cellular_componentINTAC complex
i0160240biological_processRNA polymerase II transcription initiation surveillance
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0016180biological_processsnRNA processing
j0032039cellular_componentintegrator complex
j0034243biological_processregulation of transcription elongation by RNA polymerase II
j0160232cellular_componentINTAC complex
j0160240biological_processRNA polymerase II transcription initiation surveillance
k0004521molecular_functionRNA endonuclease activity
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005654cellular_componentnucleoplasm
k0005737cellular_componentcytoplasm
k0005829cellular_componentcytosol
k0016180biological_processsnRNA processing
k0016787molecular_functionhydrolase activity
k0032039cellular_componentintegrator complex
k0034243biological_processregulation of transcription elongation by RNA polymerase II
k0034472biological_processsnRNA 3'-end processing
k0046872molecular_functionmetal ion binding
k0072562cellular_componentblood microparticle
k0160232cellular_componentINTAC complex
k0160240biological_processRNA polymerase II transcription initiation surveillance
m0005515molecular_functionprotein binding
m0005634cellular_componentnucleus
m0005654cellular_componentnucleoplasm
m0005737cellular_componentcytoplasm
m0007052biological_processmitotic spindle organization
m0007346biological_processregulation of mitotic cell cycle
m0016180biological_processsnRNA processing
m0016604cellular_componentnuclear body
m0030317biological_processflagellated sperm motility
m0032039cellular_componentintegrator complex
m0034243biological_processregulation of transcription elongation by RNA polymerase II
m0051301biological_processcell division
m0051642biological_processcentrosome localization
m0080154biological_processregulation of fertilization
m0090435biological_processprotein localization to nuclear envelope
m0140297molecular_functionDNA-binding transcription factor binding
m0160232cellular_componentINTAC complex
m0160240biological_processRNA polymerase II transcription initiation surveillance
n0005515molecular_functionprotein binding
n0005634cellular_componentnucleus
n0005654cellular_componentnucleoplasm
n0016180biological_processsnRNA processing
n0032039cellular_componentintegrator complex
n0034243biological_processregulation of transcription elongation by RNA polymerase II
n0034472biological_processsnRNA 3'-end processing
n0046872molecular_functionmetal ion binding
n0160232cellular_componentINTAC complex
n0160240biological_processRNA polymerase II transcription initiation surveillance
o0005634cellular_componentnucleus
o0005694cellular_componentchromosome
o0016180biological_processsnRNA processing
o0032039cellular_componentintegrator complex
o0034243biological_processregulation of transcription elongation by RNA polymerase II
o0160232cellular_componentINTAC complex
o0160240biological_processRNA polymerase II transcription initiation surveillance
p0000159cellular_componentprotein phosphatase type 2A complex
p0000775cellular_componentchromosome, centromeric region
p0000785cellular_componentchromatin
p0004722molecular_functionprotein serine/threonine phosphatase activity
p0005515molecular_functionprotein binding
p0005634cellular_componentnucleus
p0005694cellular_componentchromosome
p0005737cellular_componentcytoplasm
p0005739cellular_componentmitochondrion
p0005829cellular_componentcytosol
p0007059biological_processchromosome segregation
p0015630cellular_componentmicrotubule cytoskeleton
p0016020cellular_componentmembrane
p0016180biological_processsnRNA processing
p0016328cellular_componentlateral plasma membrane
p0019888molecular_functionprotein phosphatase regulator activity
p0030425cellular_componentdendrite
p0034243biological_processregulation of transcription elongation by RNA polymerase II
p0035330biological_processregulation of hippo signaling
p0035331biological_processnegative regulation of hippo signaling
p0035556biological_processintracellular signal transduction
p0040008biological_processregulation of growth
p0043005cellular_componentneuron projection
p0043025cellular_componentneuronal cell body
p0043029biological_processT cell homeostasis
p0045202cellular_componentsynapse
p0045595biological_processregulation of cell differentiation
p0046982molecular_functionprotein heterodimerization activity
p0051225biological_processspindle assembly
p0051754biological_processmeiotic sister chromatid cohesion, centromeric
p0051898biological_processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
p0065003biological_processprotein-containing complex assembly
p0070062cellular_componentextracellular exosome
p0090443cellular_componentFAR/SIN/STRIPAK complex
p0098978cellular_componentglutamatergic synapse
p0160232cellular_componentINTAC complex
p0160240biological_processRNA polymerase II transcription initiation surveillance
p1990405molecular_functionprotein antigen binding
q0000159cellular_componentprotein phosphatase type 2A complex
q0000278biological_processmitotic cell cycle
q0000775cellular_componentchromosome, centromeric region
q0000785cellular_componentchromatin
q0000922cellular_componentspindle pole
q0004721molecular_functionphosphoprotein phosphatase activity
q0004722molecular_functionprotein serine/threonine phosphatase activity
q0004725molecular_functionprotein tyrosine phosphatase activity
q0005515molecular_functionprotein binding
q0005634cellular_componentnucleus
q0005694cellular_componentchromosome
q0005737cellular_componentcytoplasm
q0005739cellular_componentmitochondrion
q0005829cellular_componentcytosol
q0005886cellular_componentplasma membrane
q0006357biological_processregulation of transcription by RNA polymerase II
q0006470biological_processprotein dephosphorylation
q0010288biological_processresponse to lead ion
q0010719biological_processnegative regulation of epithelial to mesenchymal transition
q0015630cellular_componentmicrotubule cytoskeleton
q0016020cellular_componentmembrane
q0016180biological_processsnRNA processing
q0016787molecular_functionhydrolase activity
q0031113biological_processregulation of microtubule polymerization
q0034243biological_processregulation of transcription elongation by RNA polymerase II
q0035330biological_processregulation of hippo signaling
q0035331biological_processnegative regulation of hippo signaling
q0035556biological_processintracellular signal transduction
q0040008biological_processregulation of growth
q0043029biological_processT cell homeostasis
q0045121cellular_componentmembrane raft
q0045202cellular_componentsynapse
q0045595biological_processregulation of cell differentiation
q0046872molecular_functionmetal ion binding
q0046982molecular_functionprotein heterodimerization activity
q0048156molecular_functiontau protein binding
q0050811molecular_functionGABA receptor binding
q0051321biological_processmeiotic cell cycle
q0051898biological_processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
q0070062cellular_componentextracellular exosome
q0090090biological_processnegative regulation of canonical Wnt signaling pathway
q0090443cellular_componentFAR/SIN/STRIPAK complex
q0097706biological_processvascular endothelial cell response to oscillatory fluid shear stress
q0160232cellular_componentINTAC complex
q0160240biological_processRNA polymerase II transcription initiation surveillance
q0180006molecular_functionRNA polymerase II CTD heptapeptide repeat S2 phosphatase activity
q0180007molecular_functionRNA polymerase II CTD heptapeptide repeat S5 phosphatase activity
q0180008molecular_functionRNA polymerase II CTD heptapeptide repeat S7 phosphatase activity
q1900227biological_processpositive regulation of NLRP3 inflammasome complex assembly
q1904539biological_processnegative regulation of glycolytic process through fructose-6-phosphate
q2000045biological_processregulation of G1/S transition of mitotic cell cycle
r0006406biological_processmRNA export from nucleus
r0008541cellular_componentproteasome regulatory particle, lid subcomplex
r0043248biological_processproteasome assembly
Functional Information from PROSITE/UniProt
site_idPS00019
Number of Residues10
DetailsACTININ_1 Actinin-type actin-binding domain signature 1. QPeTYYKWDN
ChainResidueDetails
aGLN620-ASN629
site_idPS00039
Number of Residues9
DetailsDEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. MIDEADEfV
ChainResidueDetails
fMET627-VAL635
site_idPS00115
Number of Residues7
DetailsRNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPS
ChainResidueDetails
YTYR1622-SER1628
site_idPS00125
Number of Residues6
DetailsSER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE
ChainResidueDetails
qLEU114-GLU119
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues70
DetailsDNA binding: {"description":"OB"}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues96
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues39
DetailsRepeat: {"description":"HEAT 1"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues36
DetailsRepeat: {"description":"HEAT 5"}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues38
DetailsRepeat: {"description":"HEAT 7"}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues38
DetailsRepeat: {"description":"HEAT 8"}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues224
DetailsDomain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues38
DetailsRepeat: {"description":"TPR 1"}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues33
DetailsRepeat: {"description":"TPR 3"}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues33
DetailsRepeat: {"description":"TPR 4"}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues5
DetailsMotif: {"description":"WFEF motif","evidences":[{"source":"PubMed","id":"32966759","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q95TS5","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q8K2A7","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues5
DetailsMotif: {"description":"HXHXDH motif"}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues1
DetailsActive site: {"evidences":[{"source":"PubMed","id":"28396433","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32697989","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33548203","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI21
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"33243860","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34762484","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570683","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CUN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8RBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8RBZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI22
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"34762484","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570683","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8RBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8RBZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI23
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"33243860","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34762484","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570683","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CUN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8RBZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI24
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"33243860","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38570683","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CUN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8RBZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI25
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"34762484","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7PKS","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI26
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q9VAH9","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI27
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"36454007","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI28
Number of Residues202
DetailsDomain: {"description":"VWFA"}
ChainResidueDetails
site_idSWS_FT_FI29
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38823386","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38906142","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EOC","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI30
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38823386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EOC","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI31
Number of Residues38
DetailsRepeat: {"description":"HEAT 1","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI32
Number of Residues37
DetailsRepeat: {"description":"HEAT 2","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI33
Number of Residues38
DetailsRepeat: {"description":"HEAT 3","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI34
Number of Residues37
DetailsRepeat: {"description":"HEAT 4","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI35
Number of Residues38
DetailsRepeat: {"description":"HEAT 5","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI36
Number of Residues38
DetailsRepeat: {"description":"HEAT 6","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI37
Number of Residues38
DetailsRepeat: {"description":"HEAT 7","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI38
Number of Residues42
DetailsRepeat: {"description":"HEAT 8","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI39
Number of Residues38
DetailsRepeat: {"description":"HEAT 9","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI40
Number of Residues38
DetailsRepeat: {"description":"HEAT 10","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI41
Number of Residues38
DetailsRepeat: {"description":"HEAT 11","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI42
Number of Residues38
DetailsRepeat: {"description":"HEAT 12","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI43
Number of Residues38
DetailsRepeat: {"description":"HEAT 13","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI44
Number of Residues38
DetailsRepeat: {"description":"HEAT 14","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI45
Number of Residues391
DetailsRegion: {"description":"PP2A subunit B binding"}
ChainResidueDetails
site_idSWS_FT_FI46
Number of Residues274
DetailsRegion: {"description":"Polyoma small and medium T antigens Binding"}
ChainResidueDetails
site_idSWS_FT_FI47
Number of Residues154
DetailsRegion: {"description":"SV40 small T antigen binding"}
ChainResidueDetails
site_idSWS_FT_FI48
Number of Residues1
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI49
Number of Residues1
DetailsActive site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P36873","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI50
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI51
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"17055435","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33243860","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33633399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34762484","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CUN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7K36","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7PKS","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI52
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"38906142","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

248335

PDB entries from 2026-01-28

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