8QZ3
Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an activatory nanobody (Nb67)
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 52 |
| Details | INTRAMEM: Pore-forming; Name=Pore-forming 1 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER154-PRO180 | |
| B | SER154-PRO180 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 120 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | THR182-PHE202 | |
| A | THR234-THR254 | |
| A | GLU299-VAL319 | |
| B | THR182-PHE202 | |
| B | THR234-THR254 | |
| B | GLU299-VAL319 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 60 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU203-GLN233 | |
| B | LEU203-GLN233 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 62 |
| Details | INTRAMEM: Pore-forming; Name=Pore-forming 2 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE263-GLY294 | |
| B | ILE263-GLY294 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL144 | |
| A | ILE147 | |
| A | GLY148 | |
| B | VAL144 | |
| B | ILE147 | |
| B | GLY148 |
