8QYS

Human preholo proteasome 20S core particle

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0000932	cellular_component	P-body
A	0002376	biological_process	immune system process
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005839	cellular_component	proteasome core complex
A	0006281	biological_process	DNA repair
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0006915	biological_process	apoptotic process
A	0006974	biological_process	DNA damage response
A	0006979	biological_process	response to oxidative stress
A	0007283	biological_process	spermatogenesis
A	0008021	cellular_component	synaptic vesicle
A	0009615	biological_process	response to virus
A	0010498	biological_process	proteasomal protein catabolic process
A	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0030317	biological_process	flagellated sperm motility
A	0032729	biological_process	positive regulation of type II interferon production
A	0032743	biological_process	positive regulation of interleukin-2 production
A	0032760	biological_process	positive regulation of tumor necrosis factor production
A	0034341	biological_process	response to type II interferon
A	0034515	cellular_component	proteasome storage granule
A	0034774	cellular_component	secretory granule lumen
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
A	0045061	biological_process	thymic T cell selection
A	0045063	biological_process	T-helper 1 cell differentiation
A	0045590	biological_process	negative regulation of regulatory T cell differentiation
A	0051321	biological_process	meiotic cell cycle
A	0051603	biological_process	proteolysis involved in protein catabolic process
A	0061136	biological_process	regulation of proteasomal protein catabolic process
A	0070062	cellular_component	extracellular exosome
A	0071357	biological_process	cellular response to type I interferon
A	0072539	biological_process	T-helper 17 cell differentiation
A	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
A	1904813	cellular_component	ficolin-1-rich granule lumen
A	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
B	0000502	cellular_component	proteasome complex
B	0000932	cellular_component	P-body
B	0002376	biological_process	immune system process
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005839	cellular_component	proteasome core complex
B	0006281	biological_process	DNA repair
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0006915	biological_process	apoptotic process
B	0006974	biological_process	DNA damage response
B	0006979	biological_process	response to oxidative stress
B	0007283	biological_process	spermatogenesis
B	0008021	cellular_component	synaptic vesicle
B	0010498	biological_process	proteasomal protein catabolic process
B	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0030317	biological_process	flagellated sperm motility
B	0032729	biological_process	positive regulation of type II interferon production
B	0032743	biological_process	positive regulation of interleukin-2 production
B	0032760	biological_process	positive regulation of tumor necrosis factor production
B	0034341	biological_process	response to type II interferon
B	0034515	cellular_component	proteasome storage granule
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
B	0045061	biological_process	thymic T cell selection
B	0045063	biological_process	T-helper 1 cell differentiation
B	0045590	biological_process	negative regulation of regulatory T cell differentiation
B	0051321	biological_process	meiotic cell cycle
B	0051603	biological_process	proteolysis involved in protein catabolic process
B	0061136	biological_process	regulation of proteasomal protein catabolic process
B	0070062	cellular_component	extracellular exosome
B	0071357	biological_process	cellular response to type I interferon
B	0072539	biological_process	T-helper 17 cell differentiation
B	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
B	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
C	0000502	cellular_component	proteasome complex
C	0002376	biological_process	immune system process
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005839	cellular_component	proteasome core complex
C	0006281	biological_process	DNA repair
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0006915	biological_process	apoptotic process
C	0006974	biological_process	DNA damage response
C	0006979	biological_process	response to oxidative stress
C	0008021	cellular_component	synaptic vesicle
C	0010498	biological_process	proteasomal protein catabolic process
C	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0030317	biological_process	flagellated sperm motility
C	0032729	biological_process	positive regulation of type II interferon production
C	0032743	biological_process	positive regulation of interleukin-2 production
C	0032760	biological_process	positive regulation of tumor necrosis factor production
C	0034341	biological_process	response to type II interferon
C	0034515	cellular_component	proteasome storage granule
C	0042802	molecular_function	identical protein binding
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
C	0045061	biological_process	thymic T cell selection
C	0045063	biological_process	T-helper 1 cell differentiation
C	0045590	biological_process	negative regulation of regulatory T cell differentiation
C	0051603	biological_process	proteolysis involved in protein catabolic process
C	0061136	biological_process	regulation of proteasomal protein catabolic process
C	0070062	cellular_component	extracellular exosome
C	0071357	biological_process	cellular response to type I interferon
C	0072539	biological_process	T-helper 17 cell differentiation
C	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
C	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
D	0000502	cellular_component	proteasome complex
D	0002376	biological_process	immune system process
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005839	cellular_component	proteasome core complex
D	0006281	biological_process	DNA repair
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0006915	biological_process	apoptotic process
D	0006974	biological_process	DNA damage response
D	0006979	biological_process	response to oxidative stress
D	0007283	biological_process	spermatogenesis
D	0008021	cellular_component	synaptic vesicle
D	0010498	biological_process	proteasomal protein catabolic process
D	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0030317	biological_process	flagellated sperm motility
D	0032729	biological_process	positive regulation of type II interferon production
D	0032743	biological_process	positive regulation of interleukin-2 production
D	0032760	biological_process	positive regulation of tumor necrosis factor production
D	0034341	biological_process	response to type II interferon
D	0034515	cellular_component	proteasome storage granule
D	0034774	cellular_component	secretory granule lumen
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
D	0045061	biological_process	thymic T cell selection
D	0045063	biological_process	T-helper 1 cell differentiation
D	0045590	biological_process	negative regulation of regulatory T cell differentiation
D	0051321	biological_process	meiotic cell cycle
D	0051603	biological_process	proteolysis involved in protein catabolic process
D	0061136	biological_process	regulation of proteasomal protein catabolic process
D	0070062	cellular_component	extracellular exosome
D	0071357	biological_process	cellular response to type I interferon
D	0072539	biological_process	T-helper 17 cell differentiation
D	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
D	1904813	cellular_component	ficolin-1-rich granule lumen
D	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
E	0000502	cellular_component	proteasome complex
E	0001530	molecular_function	lipopolysaccharide binding
E	0002376	biological_process	immune system process
E	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005839	cellular_component	proteasome core complex
E	0006281	biological_process	DNA repair
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0006915	biological_process	apoptotic process
E	0006974	biological_process	DNA damage response
E	0006979	biological_process	response to oxidative stress
E	0007283	biological_process	spermatogenesis
E	0008021	cellular_component	synaptic vesicle
E	0010498	biological_process	proteasomal protein catabolic process
E	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
E	0016604	cellular_component	nuclear body
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0030317	biological_process	flagellated sperm motility
E	0032729	biological_process	positive regulation of type II interferon production
E	0032743	biological_process	positive regulation of interleukin-2 production
E	0032760	biological_process	positive regulation of tumor necrosis factor production
E	0034341	biological_process	response to type II interferon
E	0034515	cellular_component	proteasome storage granule
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
E	0045061	biological_process	thymic T cell selection
E	0045063	biological_process	T-helper 1 cell differentiation
E	0045590	biological_process	negative regulation of regulatory T cell differentiation
E	0051321	biological_process	meiotic cell cycle
E	0051603	biological_process	proteolysis involved in protein catabolic process
E	0061136	biological_process	regulation of proteasomal protein catabolic process
E	0070062	cellular_component	extracellular exosome
E	0071357	biological_process	cellular response to type I interferon
E	0072539	biological_process	T-helper 17 cell differentiation
E	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
E	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
F	0000502	cellular_component	proteasome complex
F	0002376	biological_process	immune system process
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005839	cellular_component	proteasome core complex
F	0006281	biological_process	DNA repair
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0006915	biological_process	apoptotic process
F	0006974	biological_process	DNA damage response
F	0006979	biological_process	response to oxidative stress
F	0007283	biological_process	spermatogenesis
F	0008021	cellular_component	synaptic vesicle
F	0010498	biological_process	proteasomal protein catabolic process
F	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0030317	biological_process	flagellated sperm motility
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032729	biological_process	positive regulation of type II interferon production
F	0032743	biological_process	positive regulation of interleukin-2 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0034341	biological_process	response to type II interferon
F	0034515	cellular_component	proteasome storage granule
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
F	0045061	biological_process	thymic T cell selection
F	0045063	biological_process	T-helper 1 cell differentiation
F	0045590	biological_process	negative regulation of regulatory T cell differentiation
F	0051321	biological_process	meiotic cell cycle
F	0051603	biological_process	proteolysis involved in protein catabolic process
F	0061136	biological_process	regulation of proteasomal protein catabolic process
F	0070062	cellular_component	extracellular exosome
F	0071357	biological_process	cellular response to type I interferon
F	0072539	biological_process	T-helper 17 cell differentiation
F	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
F	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
G	0000502	cellular_component	proteasome complex
G	0000932	cellular_component	P-body
G	0002376	biological_process	immune system process
G	0003723	molecular_function	RNA binding
G	0004175	molecular_function	endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0005840	cellular_component	ribosome
G	0006281	biological_process	DNA repair
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006915	biological_process	apoptotic process
G	0006974	biological_process	DNA damage response
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0008021	cellular_component	synaptic vesicle
G	0010498	biological_process	proteasomal protein catabolic process
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0016363	cellular_component	nuclear matrix
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0030317	biological_process	flagellated sperm motility
G	0032729	biological_process	positive regulation of type II interferon production
G	0032743	biological_process	positive regulation of interleukin-2 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0034341	biological_process	response to type II interferon
G	0034515	cellular_component	proteasome storage granule
G	0035639	molecular_function	purine ribonucleoside triphosphate binding
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
G	0045061	biological_process	thymic T cell selection
G	0045063	biological_process	T-helper 1 cell differentiation
G	0045590	biological_process	negative regulation of regulatory T cell differentiation
G	0050727	biological_process	regulation of inflammatory response
G	0051059	molecular_function	NF-kappaB binding
G	0051321	biological_process	meiotic cell cycle
G	0051603	biological_process	proteolysis involved in protein catabolic process
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0070062	cellular_component	extracellular exosome
G	0071357	biological_process	cellular response to type I interferon
G	0072539	biological_process	T-helper 17 cell differentiation
G	0097229	cellular_component	sperm end piece
G	0097542	cellular_component	ciliary tip
G	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0016607	cellular_component	nuclear speck
H	0043248	biological_process	proteasome assembly
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005783	cellular_component	endoplasmic reticulum
I	0005794	cellular_component	Golgi apparatus
I	0005829	cellular_component	cytosol
I	0043248	biological_process	proteasome assembly
I	0051131	biological_process	chaperone-mediated protein complex assembly
I	0060090	molecular_function	molecular adaptor activity
I	0070628	molecular_function	proteasome binding
I	0080129	biological_process	proteasome core complex assembly
I	0101031	cellular_component	protein folding chaperone complex
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005829	cellular_component	cytosol
J	0043248	biological_process	proteasome assembly
J	0051131	biological_process	chaperone-mediated protein complex assembly
J	0060090	molecular_function	molecular adaptor activity
J	0080129	biological_process	proteasome core complex assembly
J	0101031	cellular_component	protein folding chaperone complex
K	0000502	cellular_component	proteasome complex
K	0004175	molecular_function	endopeptidase activity
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005839	cellular_component	proteasome core complex
K	0006281	biological_process	DNA repair
K	0006508	biological_process	proteolysis
K	0006915	biological_process	apoptotic process
K	0006974	biological_process	DNA damage response
K	0006979	biological_process	response to oxidative stress
K	0007283	biological_process	spermatogenesis
K	0008021	cellular_component	synaptic vesicle
K	0008233	molecular_function	peptidase activity
K	0010498	biological_process	proteasomal protein catabolic process
K	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
K	0016604	cellular_component	nuclear body
K	0016787	molecular_function	hydrolase activity
K	0019774	cellular_component	proteasome core complex, beta-subunit complex
K	0030317	biological_process	flagellated sperm motility
K	0034515	cellular_component	proteasome storage granule
K	0034774	cellular_component	secretory granule lumen
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0051321	biological_process	meiotic cell cycle
K	0051603	biological_process	proteolysis involved in protein catabolic process
K	0061136	biological_process	regulation of proteasomal protein catabolic process
K	0071357	biological_process	cellular response to type I interferon
K	1904813	cellular_component	ficolin-1-rich granule lumen
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
L	0000502	cellular_component	proteasome complex
L	0002376	biological_process	immune system process
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005839	cellular_component	proteasome core complex
L	0006281	biological_process	DNA repair
L	0006915	biological_process	apoptotic process
L	0006974	biological_process	DNA damage response
L	0006979	biological_process	response to oxidative stress
L	0007283	biological_process	spermatogenesis
L	0008021	cellular_component	synaptic vesicle
L	0010498	biological_process	proteasomal protein catabolic process
L	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
L	0019774	cellular_component	proteasome core complex, beta-subunit complex
L	0030317	biological_process	flagellated sperm motility
L	0032729	biological_process	positive regulation of type II interferon production
L	0032743	biological_process	positive regulation of interleukin-2 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0034341	biological_process	response to type II interferon
L	0034515	cellular_component	proteasome storage granule
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
L	0045061	biological_process	thymic T cell selection
L	0045063	biological_process	T-helper 1 cell differentiation
L	0045590	biological_process	negative regulation of regulatory T cell differentiation
L	0051321	biological_process	meiotic cell cycle
L	0051603	biological_process	proteolysis involved in protein catabolic process
L	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0070062	cellular_component	extracellular exosome
L	0071357	biological_process	cellular response to type I interferon
L	0072539	biological_process	T-helper 17 cell differentiation
L	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
M	0000502	cellular_component	proteasome complex
M	0002376	biological_process	immune system process
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005839	cellular_component	proteasome core complex
M	0006281	biological_process	DNA repair
M	0006915	biological_process	apoptotic process
M	0006974	biological_process	DNA damage response
M	0006979	biological_process	response to oxidative stress
M	0007283	biological_process	spermatogenesis
M	0008021	cellular_component	synaptic vesicle
M	0010498	biological_process	proteasomal protein catabolic process
M	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
M	0016020	cellular_component	membrane
M	0019774	cellular_component	proteasome core complex, beta-subunit complex
M	0030317	biological_process	flagellated sperm motility
M	0032729	biological_process	positive regulation of type II interferon production
M	0032743	biological_process	positive regulation of interleukin-2 production
M	0032760	biological_process	positive regulation of tumor necrosis factor production
M	0034341	biological_process	response to type II interferon
M	0034515	cellular_component	proteasome storage granule
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
M	0045061	biological_process	thymic T cell selection
M	0045063	biological_process	T-helper 1 cell differentiation
M	0045590	biological_process	negative regulation of regulatory T cell differentiation
M	0051321	biological_process	meiotic cell cycle
M	0051603	biological_process	proteolysis involved in protein catabolic process
M	0061136	biological_process	regulation of proteasomal protein catabolic process
M	0070062	cellular_component	extracellular exosome
M	0071357	biological_process	cellular response to type I interferon
M	0072539	biological_process	T-helper 17 cell differentiation
M	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005839	cellular_component	proteasome core complex
N	0051603	biological_process	proteolysis involved in protein catabolic process
O	0005839	cellular_component	proteasome core complex
O	0051603	biological_process	proteolysis involved in protein catabolic process
P	0005839	cellular_component	proteasome core complex
P	0051603	biological_process	proteolysis involved in protein catabolic process
Q	0004298	molecular_function	threonine-type endopeptidase activity
Q	0005839	cellular_component	proteasome core complex
Q	0051603	biological_process	proteolysis involved in protein catabolic process
R	0000502	cellular_component	proteasome complex
R	0000932	cellular_component	P-body
R	0002376	biological_process	immune system process
R	0005515	molecular_function	protein binding
R	0005576	cellular_component	extracellular region
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005839	cellular_component	proteasome core complex
R	0006281	biological_process	DNA repair
R	0006511	biological_process	ubiquitin-dependent protein catabolic process
R	0006915	biological_process	apoptotic process
R	0006974	biological_process	DNA damage response
R	0006979	biological_process	response to oxidative stress
R	0007283	biological_process	spermatogenesis
R	0008021	cellular_component	synaptic vesicle
R	0009615	biological_process	response to virus
R	0010498	biological_process	proteasomal protein catabolic process
R	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
R	0019773	cellular_component	proteasome core complex, alpha-subunit complex
R	0030317	biological_process	flagellated sperm motility
R	0032729	biological_process	positive regulation of type II interferon production
R	0032743	biological_process	positive regulation of interleukin-2 production
R	0032760	biological_process	positive regulation of tumor necrosis factor production
R	0034341	biological_process	response to type II interferon
R	0034515	cellular_component	proteasome storage granule
R	0034774	cellular_component	secretory granule lumen
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
R	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
R	0045061	biological_process	thymic T cell selection
R	0045063	biological_process	T-helper 1 cell differentiation
R	0045590	biological_process	negative regulation of regulatory T cell differentiation
R	0051321	biological_process	meiotic cell cycle
R	0051603	biological_process	proteolysis involved in protein catabolic process
R	0061136	biological_process	regulation of proteasomal protein catabolic process
R	0070062	cellular_component	extracellular exosome
R	0071357	biological_process	cellular response to type I interferon
R	0072539	biological_process	T-helper 17 cell differentiation
R	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
R	1904813	cellular_component	ficolin-1-rich granule lumen
R	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
S	0000502	cellular_component	proteasome complex
S	0000932	cellular_component	P-body
S	0002376	biological_process	immune system process
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005839	cellular_component	proteasome core complex
S	0006281	biological_process	DNA repair
S	0006511	biological_process	ubiquitin-dependent protein catabolic process
S	0006915	biological_process	apoptotic process
S	0006974	biological_process	DNA damage response
S	0006979	biological_process	response to oxidative stress
S	0007283	biological_process	spermatogenesis
S	0008021	cellular_component	synaptic vesicle
S	0010498	biological_process	proteasomal protein catabolic process
S	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
S	0019773	cellular_component	proteasome core complex, alpha-subunit complex
S	0030317	biological_process	flagellated sperm motility
S	0032729	biological_process	positive regulation of type II interferon production
S	0032743	biological_process	positive regulation of interleukin-2 production
S	0032760	biological_process	positive regulation of tumor necrosis factor production
S	0034341	biological_process	response to type II interferon
S	0034515	cellular_component	proteasome storage granule
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
S	0045061	biological_process	thymic T cell selection
S	0045063	biological_process	T-helper 1 cell differentiation
S	0045590	biological_process	negative regulation of regulatory T cell differentiation
S	0051321	biological_process	meiotic cell cycle
S	0051603	biological_process	proteolysis involved in protein catabolic process
S	0061136	biological_process	regulation of proteasomal protein catabolic process
S	0070062	cellular_component	extracellular exosome
S	0071357	biological_process	cellular response to type I interferon
S	0072539	biological_process	T-helper 17 cell differentiation
S	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
S	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
T	0000502	cellular_component	proteasome complex
T	0002376	biological_process	immune system process
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005839	cellular_component	proteasome core complex
T	0006281	biological_process	DNA repair
T	0006511	biological_process	ubiquitin-dependent protein catabolic process
T	0006915	biological_process	apoptotic process
T	0006974	biological_process	DNA damage response
T	0006979	biological_process	response to oxidative stress
T	0008021	cellular_component	synaptic vesicle
T	0010498	biological_process	proteasomal protein catabolic process
T	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
T	0019773	cellular_component	proteasome core complex, alpha-subunit complex
T	0030317	biological_process	flagellated sperm motility
T	0032729	biological_process	positive regulation of type II interferon production
T	0032743	biological_process	positive regulation of interleukin-2 production
T	0032760	biological_process	positive regulation of tumor necrosis factor production
T	0034341	biological_process	response to type II interferon
T	0034515	cellular_component	proteasome storage granule
T	0042802	molecular_function	identical protein binding
T	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
T	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
T	0045061	biological_process	thymic T cell selection
T	0045063	biological_process	T-helper 1 cell differentiation
T	0045590	biological_process	negative regulation of regulatory T cell differentiation
T	0051603	biological_process	proteolysis involved in protein catabolic process
T	0061136	biological_process	regulation of proteasomal protein catabolic process
T	0070062	cellular_component	extracellular exosome
T	0071357	biological_process	cellular response to type I interferon
T	0072539	biological_process	T-helper 17 cell differentiation
T	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
T	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
U	0000502	cellular_component	proteasome complex
U	0002376	biological_process	immune system process
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005839	cellular_component	proteasome core complex
U	0006281	biological_process	DNA repair
U	0006511	biological_process	ubiquitin-dependent protein catabolic process
U	0006915	biological_process	apoptotic process
U	0006974	biological_process	DNA damage response
U	0006979	biological_process	response to oxidative stress
U	0007283	biological_process	spermatogenesis
U	0008021	cellular_component	synaptic vesicle
U	0010498	biological_process	proteasomal protein catabolic process
U	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
U	0019773	cellular_component	proteasome core complex, alpha-subunit complex
U	0030317	biological_process	flagellated sperm motility
U	0032729	biological_process	positive regulation of type II interferon production
U	0032743	biological_process	positive regulation of interleukin-2 production
U	0032760	biological_process	positive regulation of tumor necrosis factor production
U	0034341	biological_process	response to type II interferon
U	0034515	cellular_component	proteasome storage granule
U	0034774	cellular_component	secretory granule lumen
U	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
U	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
U	0045061	biological_process	thymic T cell selection
U	0045063	biological_process	T-helper 1 cell differentiation
U	0045590	biological_process	negative regulation of regulatory T cell differentiation
U	0051321	biological_process	meiotic cell cycle
U	0051603	biological_process	proteolysis involved in protein catabolic process
U	0061136	biological_process	regulation of proteasomal protein catabolic process
U	0070062	cellular_component	extracellular exosome
U	0071357	biological_process	cellular response to type I interferon
U	0072539	biological_process	T-helper 17 cell differentiation
U	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
U	1904813	cellular_component	ficolin-1-rich granule lumen
U	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
V	0000502	cellular_component	proteasome complex
V	0001530	molecular_function	lipopolysaccharide binding
V	0002376	biological_process	immune system process
V	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005839	cellular_component	proteasome core complex
V	0006281	biological_process	DNA repair
V	0006511	biological_process	ubiquitin-dependent protein catabolic process
V	0006915	biological_process	apoptotic process
V	0006974	biological_process	DNA damage response
V	0006979	biological_process	response to oxidative stress
V	0007283	biological_process	spermatogenesis
V	0008021	cellular_component	synaptic vesicle
V	0010498	biological_process	proteasomal protein catabolic process
V	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
V	0016604	cellular_component	nuclear body
V	0019773	cellular_component	proteasome core complex, alpha-subunit complex
V	0030317	biological_process	flagellated sperm motility
V	0032729	biological_process	positive regulation of type II interferon production
V	0032743	biological_process	positive regulation of interleukin-2 production
V	0032760	biological_process	positive regulation of tumor necrosis factor production
V	0034341	biological_process	response to type II interferon
V	0034515	cellular_component	proteasome storage granule
V	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
V	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
V	0045061	biological_process	thymic T cell selection
V	0045063	biological_process	T-helper 1 cell differentiation
V	0045590	biological_process	negative regulation of regulatory T cell differentiation
V	0051321	biological_process	meiotic cell cycle
V	0051603	biological_process	proteolysis involved in protein catabolic process
V	0061136	biological_process	regulation of proteasomal protein catabolic process
V	0070062	cellular_component	extracellular exosome
V	0071357	biological_process	cellular response to type I interferon
V	0072539	biological_process	T-helper 17 cell differentiation
V	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
V	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
W	0000502	cellular_component	proteasome complex
W	0002376	biological_process	immune system process
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005839	cellular_component	proteasome core complex
W	0006281	biological_process	DNA repair
W	0006511	biological_process	ubiquitin-dependent protein catabolic process
W	0006915	biological_process	apoptotic process
W	0006974	biological_process	DNA damage response
W	0006979	biological_process	response to oxidative stress
W	0007283	biological_process	spermatogenesis
W	0008021	cellular_component	synaptic vesicle
W	0010498	biological_process	proteasomal protein catabolic process
W	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
W	0019773	cellular_component	proteasome core complex, alpha-subunit complex
W	0030317	biological_process	flagellated sperm motility
W	0031625	molecular_function	ubiquitin protein ligase binding
W	0032729	biological_process	positive regulation of type II interferon production
W	0032743	biological_process	positive regulation of interleukin-2 production
W	0032760	biological_process	positive regulation of tumor necrosis factor production
W	0034341	biological_process	response to type II interferon
W	0034515	cellular_component	proteasome storage granule
W	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
W	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
W	0045061	biological_process	thymic T cell selection
W	0045063	biological_process	T-helper 1 cell differentiation
W	0045590	biological_process	negative regulation of regulatory T cell differentiation
W	0051321	biological_process	meiotic cell cycle
W	0051603	biological_process	proteolysis involved in protein catabolic process
W	0061136	biological_process	regulation of proteasomal protein catabolic process
W	0070062	cellular_component	extracellular exosome
W	0071357	biological_process	cellular response to type I interferon
W	0072539	biological_process	T-helper 17 cell differentiation
W	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
W	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
X	0000502	cellular_component	proteasome complex
X	0000932	cellular_component	P-body
X	0002376	biological_process	immune system process
X	0003723	molecular_function	RNA binding
X	0004175	molecular_function	endopeptidase activity
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005839	cellular_component	proteasome core complex
X	0005840	cellular_component	ribosome
X	0006281	biological_process	DNA repair
X	0006511	biological_process	ubiquitin-dependent protein catabolic process
X	0006915	biological_process	apoptotic process
X	0006974	biological_process	DNA damage response
X	0006979	biological_process	response to oxidative stress
X	0007283	biological_process	spermatogenesis
X	0008021	cellular_component	synaptic vesicle
X	0010498	biological_process	proteasomal protein catabolic process
X	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
X	0016363	cellular_component	nuclear matrix
X	0019773	cellular_component	proteasome core complex, alpha-subunit complex
X	0030016	cellular_component	myofibril
X	0030017	cellular_component	sarcomere
X	0030317	biological_process	flagellated sperm motility
X	0032729	biological_process	positive regulation of type II interferon production
X	0032743	biological_process	positive regulation of interleukin-2 production
X	0032760	biological_process	positive regulation of tumor necrosis factor production
X	0034341	biological_process	response to type II interferon
X	0034515	cellular_component	proteasome storage granule
X	0035639	molecular_function	purine ribonucleoside triphosphate binding
X	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
X	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
X	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
X	0045061	biological_process	thymic T cell selection
X	0045063	biological_process	T-helper 1 cell differentiation
X	0045590	biological_process	negative regulation of regulatory T cell differentiation
X	0050727	biological_process	regulation of inflammatory response
X	0051059	molecular_function	NF-kappaB binding
X	0051321	biological_process	meiotic cell cycle
X	0051603	biological_process	proteolysis involved in protein catabolic process
X	0061136	biological_process	regulation of proteasomal protein catabolic process
X	0070062	cellular_component	extracellular exosome
X	0071357	biological_process	cellular response to type I interferon
X	0072539	biological_process	T-helper 17 cell differentiation
X	0097229	cellular_component	sperm end piece
X	0097542	cellular_component	ciliary tip
X	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
X	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
Y	0005634	cellular_component	nucleus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0016607	cellular_component	nuclear speck
Y	0043248	biological_process	proteasome assembly
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0005794	cellular_component	Golgi apparatus
Z	0005829	cellular_component	cytosol
Z	0043248	biological_process	proteasome assembly
Z	0051131	biological_process	chaperone-mediated protein complex assembly
Z	0060090	molecular_function	molecular adaptor activity
Z	0070628	molecular_function	proteasome binding
Z	0080129	biological_process	proteasome core complex assembly
Z	0101031	cellular_component	protein folding chaperone complex
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005829	cellular_component	cytosol
a	0043248	biological_process	proteasome assembly
a	0051131	biological_process	chaperone-mediated protein complex assembly
a	0060090	molecular_function	molecular adaptor activity
a	0080129	biological_process	proteasome core complex assembly
a	0101031	cellular_component	protein folding chaperone complex
b	0000502	cellular_component	proteasome complex
b	0004175	molecular_function	endopeptidase activity
b	0004298	molecular_function	threonine-type endopeptidase activity
b	0005515	molecular_function	protein binding
b	0005576	cellular_component	extracellular region
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005839	cellular_component	proteasome core complex
b	0006281	biological_process	DNA repair
b	0006508	biological_process	proteolysis
b	0006915	biological_process	apoptotic process
b	0006974	biological_process	DNA damage response
b	0006979	biological_process	response to oxidative stress
b	0007283	biological_process	spermatogenesis
b	0008021	cellular_component	synaptic vesicle
b	0008233	molecular_function	peptidase activity
b	0010498	biological_process	proteasomal protein catabolic process
b	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
b	0016604	cellular_component	nuclear body
b	0016787	molecular_function	hydrolase activity
b	0019774	cellular_component	proteasome core complex, beta-subunit complex
b	0030317	biological_process	flagellated sperm motility
b	0034515	cellular_component	proteasome storage granule
b	0034774	cellular_component	secretory granule lumen
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
b	0051321	biological_process	meiotic cell cycle
b	0051603	biological_process	proteolysis involved in protein catabolic process
b	0061136	biological_process	regulation of proteasomal protein catabolic process
b	0071357	biological_process	cellular response to type I interferon
b	1904813	cellular_component	ficolin-1-rich granule lumen
b	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
c	0000502	cellular_component	proteasome complex
c	0002376	biological_process	immune system process
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005839	cellular_component	proteasome core complex
c	0006281	biological_process	DNA repair
c	0006915	biological_process	apoptotic process
c	0006974	biological_process	DNA damage response
c	0006979	biological_process	response to oxidative stress
c	0007283	biological_process	spermatogenesis
c	0008021	cellular_component	synaptic vesicle
c	0010498	biological_process	proteasomal protein catabolic process
c	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
c	0019774	cellular_component	proteasome core complex, beta-subunit complex
c	0030317	biological_process	flagellated sperm motility
c	0032729	biological_process	positive regulation of type II interferon production
c	0032743	biological_process	positive regulation of interleukin-2 production
c	0032760	biological_process	positive regulation of tumor necrosis factor production
c	0034341	biological_process	response to type II interferon
c	0034515	cellular_component	proteasome storage granule
c	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
c	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
c	0045061	biological_process	thymic T cell selection
c	0045063	biological_process	T-helper 1 cell differentiation
c	0045590	biological_process	negative regulation of regulatory T cell differentiation
c	0051321	biological_process	meiotic cell cycle
c	0051603	biological_process	proteolysis involved in protein catabolic process
c	0061136	biological_process	regulation of proteasomal protein catabolic process
c	0070062	cellular_component	extracellular exosome
c	0071357	biological_process	cellular response to type I interferon
c	0072539	biological_process	T-helper 17 cell differentiation
c	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
c	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
d	0000502	cellular_component	proteasome complex
d	0002376	biological_process	immune system process
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005839	cellular_component	proteasome core complex
d	0006281	biological_process	DNA repair
d	0006915	biological_process	apoptotic process
d	0006974	biological_process	DNA damage response
d	0006979	biological_process	response to oxidative stress
d	0007283	biological_process	spermatogenesis
d	0008021	cellular_component	synaptic vesicle
d	0010498	biological_process	proteasomal protein catabolic process
d	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
d	0016020	cellular_component	membrane
d	0019774	cellular_component	proteasome core complex, beta-subunit complex
d	0030317	biological_process	flagellated sperm motility
d	0032729	biological_process	positive regulation of type II interferon production
d	0032743	biological_process	positive regulation of interleukin-2 production
d	0032760	biological_process	positive regulation of tumor necrosis factor production
d	0034341	biological_process	response to type II interferon
d	0034515	cellular_component	proteasome storage granule
d	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
d	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
d	0045061	biological_process	thymic T cell selection
d	0045063	biological_process	T-helper 1 cell differentiation
d	0045590	biological_process	negative regulation of regulatory T cell differentiation
d	0051321	biological_process	meiotic cell cycle
d	0051603	biological_process	proteolysis involved in protein catabolic process
d	0061136	biological_process	regulation of proteasomal protein catabolic process
d	0070062	cellular_component	extracellular exosome
d	0071357	biological_process	cellular response to type I interferon
d	0072539	biological_process	T-helper 17 cell differentiation
d	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
d	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
e	0004298	molecular_function	threonine-type endopeptidase activity
e	0005839	cellular_component	proteasome core complex
e	0051603	biological_process	proteolysis involved in protein catabolic process
f	0005839	cellular_component	proteasome core complex
f	0051603	biological_process	proteolysis involved in protein catabolic process
g	0005839	cellular_component	proteasome core complex
g	0051603	biological_process	proteolysis involved in protein catabolic process
h	0004298	molecular_function	threonine-type endopeptidase activity
h	0005839	cellular_component	proteasome core complex
h	0051603	biological_process	proteolysis involved in protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdndvTvWSPqGRihQIEYAmeA

Chain	Residue	Details
E	TYR6-ALA28
C	TYR3-ALA25
F	TYR8-ALA30
G	PHE9-ALA31
A	TYR6-ALA28
D	TYR8-ALA30
B	TYR5-ALA27

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAVqFdgGVVLGADsrtttgsyianrvtd.KltpihdrifccrsGsaAD

Chain	Residue	Details
h	MET38-ASP85
e	LEU63-ASP110
f	LEU41-ASP88
B	LEU35-ASP82
b	ALA47-ASP94
c	MET12-ASP59
d	ILE5-ASP52
g	LEU57-ASP104

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49722","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	26
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1 and ABL2","evidences":[{"source":"PubMed","id":"16678104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	10
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"Q9Z2U1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"P18420","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	8
Details	Motif: {"description":"High-affinity association with the preproteasome"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"25599644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27493187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18502982","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18565852","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19426847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O09061","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---