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8QH4

Crystal structure of reduced respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to oxidized 3-acetylpyridine adenine dinucleotide

Functional Information from GO Data
ChainGOidnamespacecontents
A0003954molecular_functionNADH dehydrogenase activity
A0016491molecular_functionoxidoreductase activity
A0022904biological_processrespiratory electron transport chain
A0046872molecular_functionmetal ion binding
A0048038molecular_functionquinone binding
A0051537molecular_function2 iron, 2 sulfur cluster binding
B0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
B0010181molecular_functionFMN binding
B0046872molecular_functionmetal ion binding
B0048038molecular_functionquinone binding
B0051539molecular_function4 iron, 4 sulfur cluster binding
B1902600biological_processproton transmembrane transport
C0003954molecular_functionNADH dehydrogenase activity
C0016491molecular_functionoxidoreductase activity
C0022904biological_processrespiratory electron transport chain
C0046872molecular_functionmetal ion binding
C0048038molecular_functionquinone binding
C0051537molecular_function2 iron, 2 sulfur cluster binding
D0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D0010181molecular_functionFMN binding
D0046872molecular_functionmetal ion binding
D0048038molecular_functionquinone binding
D0051539molecular_function4 iron, 4 sulfur cluster binding
D1902600biological_processproton transmembrane transport
Functional Information from PROSITE/UniProt
site_idPS00107
Number of Residues24
DetailsPROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGFGGTGTVIvLteeddive..........AALK
ChainResidueDetails
BLEU314-LYS337

site_idPS00644
Number of Residues16
DetailsCOMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES
ChainResidueDetails
BGLY176-SER191

site_idPS00645
Number of Residues12
DetailsCOMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ETCGqCtPCRvG
ChainResidueDetails
BGLU345-GLY356

site_idPS01099
Number of Residues19
DetailsCOMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DgkFKivpvqCLGaCseAP
ChainResidueDetails
AASP117-PRO135

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BGLY65
BGLY176
DGLY65
DGLY176
CCYS86
CCYS91
CCYS127
CCYS131

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
BCYS347
BCYS350
BCYS353
BCYS393
DCYS347
DCYS350
DCYS353
DCYS393

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PDB entries from 2024-11-06

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