8PAU
Crystal structure of MAP4K1 with a SMOL inhibitor
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGGGTYGEVFkArdkvsgdl..........VALK |
| Chain | Residue | Details |
| A | LEU23-LYS46 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159 |
| Chain | Residue | Details |
| A | ASP137 | |
| B | ASP137 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 |
| Chain | Residue | Details |
| A | LEU23 | |
| A | LYS46 | |
| B | LEU23 | |
| B | LYS46 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by autocatalysis => ECO:0000269|PubMed:24362026 |
| Chain | Residue | Details |
| A | THR165 | |
| A | THR175 | |
| B | THR165 | |
| B | THR175 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by autocatalysis => ECO:0000269|PubMed:24362026 |
| Chain | Residue | Details |
| A | SER171 | |
| B | SER171 |
