8P3H
Fusion hSlp2-a_Rab27A bound to covalent hit fragment IMP-1712
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0031267 | molecular_function | small GTPase binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0031267 | molecular_function | small GTPase binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Region: {"description":"Switch-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00753","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Region: {"description":"Switch-II","evidences":[{"source":"PROSITE-ProRule","id":"PRU00753","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 26 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35308027","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7OPP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7OPQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7OPR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35308027","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OPP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7OPQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7OPR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
