8P1H
Crystal structure of the chimera of human 14-3-3 zeta and phosphorylated cytoplasmic loop fragment of the alpha7 acetylcholine receptor
Functional Information from PROSITE/UniProt
| site_id | PS00796 |
| Number of Residues | 11 |
| Details | 1433_1 14-3-3 proteins signature 1. RNLLSVAYKNV |
| Chain | Residue | Details |
| A | ARG41-VAL51 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Interaction with phosphoserine on interacting protein => ECO:0000250|UniProtKB:P63103 |
| Chain | Residue | Details |
| A | ARG56 | |
| A | ARG127 | |
| B | ARG56 | |
| B | ARG127 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.8, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS3 | |
| A | LYS68 | |
| B | LYS3 | |
| B | LYS68 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKA and PKB/AKT1 => ECO:0000269|PubMed:11956222, ECO:0000269|PubMed:12865427, ECO:0000269|PubMed:15883165, ECO:0000269|PubMed:16376338 |
| Chain | Residue | Details |
| A | ALA58 | |
| B | ALA58 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by MAPK8 => ECO:0000269|PubMed:15071501, ECO:0000269|PubMed:15696159 |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | SER207 | |
| B | SER207 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63102 |
| Chain | Residue | Details |
| A | SER210 | |
| B | SER210 |
