8K4Q

Crystal structure of nanobody HuNb103 bound to human interleukin-4 receptor subunit alpha

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002532	biological_process	production of molecular mediator involved in inflammatory response
A	0004896	molecular_function	cytokine receptor activity
A	0016020	cellular_component	membrane
C	0002532	biological_process	production of molecular mediator involved in inflammatory response
C	0004896	molecular_function	cytokine receptor activity
C	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS01355
Number of Residues	31
Details	HEMATOPO_REC_S_F1 Short hematopoietin receptor family 1 signature. LksgisyrarVRawaqcyntt...........WSeWSpstkW

Chain	Residue	Details
A	LEU166-TRP196

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	8
Details	Motif: {"description":"WSXWS motif"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Site: {"description":"Major IL4 binding determinant"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Site: {"description":"Minor IL4 binding determinant"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---