8JY8

Structure of TbAQP2 in complex with anti-trypanosomatid drug pentamidine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006833	biological_process	water transport
A	0015204	molecular_function	urea transmembrane transporter activity
A	0015250	molecular_function	water channel activity
A	0015254	molecular_function	glycerol channel activity
A	0015267	molecular_function	channel activity
A	0015793	biological_process	glycerol transmembrane transport
A	0016020	cellular_component	membrane
A	0055085	biological_process	transmembrane transport
A	0071918	biological_process	urea transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006833	biological_process	water transport
B	0015204	molecular_function	urea transmembrane transporter activity
B	0015250	molecular_function	water channel activity
B	0015254	molecular_function	glycerol channel activity
B	0015267	molecular_function	channel activity
B	0015793	biological_process	glycerol transmembrane transport
B	0016020	cellular_component	membrane
B	0055085	biological_process	transmembrane transport
B	0071918	biological_process	urea transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006833	biological_process	water transport
C	0015204	molecular_function	urea transmembrane transporter activity
C	0015250	molecular_function	water channel activity
C	0015254	molecular_function	glycerol channel activity
C	0015267	molecular_function	channel activity
C	0015793	biological_process	glycerol transmembrane transport
C	0016020	cellular_component	membrane
C	0055085	biological_process	transmembrane transport
C	0071918	biological_process	urea transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006833	biological_process	water transport
D	0015204	molecular_function	urea transmembrane transporter activity
D	0015250	molecular_function	water channel activity
D	0015254	molecular_function	glycerol channel activity
D	0015267	molecular_function	channel activity
D	0015793	biological_process	glycerol transmembrane transport
D	0016020	cellular_component	membrane
D	0055085	biological_process	transmembrane transport
D	0071918	biological_process	urea transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	480
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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