8JO4

Cryo-EM structure of a Legionella effector complexed with actin and ATP

Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
B	TYR55-GLY65

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site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
B	TRP358-GLU366

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site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
B	LEU106-ARG118

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylcysteine; in intermediate form => ECO:0000250|UniProtKB:P62737

Chain	Residue	Details
B	CYS2

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:1150665

Chain	Residue	Details
B	ASP3

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134

Chain	Residue	Details
B	MET46
B	MET49

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-malonyllysine => ECO:0000250

Chain	Residue	Details
B	LYS63

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:1150665, ECO:0000269|PubMed:16905096, ECO:0000269|PubMed:213279, ECO:0000269|PubMed:2395459, ECO:0000269|PubMed:499690, ECO:0007744|PDB:1ATN, ECO:0007744|PDB:1NWK

Chain	Residue	Details
B	HIS75

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133

Chain	Residue	Details
B	LYS86

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site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: ADP-ribosylarginine; by SpvB => ECO:0000305|PubMed:16905096

Chain	Residue	Details
B	ARG179

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