8JF3
C-Src in complex with compound 9
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 23 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGCFGEVWmGtwngttr...........VAIK |
| Chain | Residue | Details |
| A | LEU276-LYS298 |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLRAANILV |
| Chain | Residue | Details |
| A | TYR385-VAL397 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | ASP389 | |
| B | ASP389 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LEU276 | |
| A | LYS298 | |
| B | LEU276 | |
| B | LYS298 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by FAK2 => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR419 | |
| B | TYR419 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by CSK => ECO:0000269|PubMed:19307596, ECO:0000269|PubMed:26936507, ECO:0000269|PubMed:7525268, ECO:0000269|PubMed:7929427, ECO:0007744|PubMed:19369195 |
| Chain | Residue | Details |
| A | TYR530 | |
| B | TYR530 |
