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8JEO

Crystal structure of TIGIT in complexed with Tiragolumab

Functional Information from GO Data
ChainGOidnamespacecontents
A0005102molecular_functionsignaling receptor binding
A0050868biological_processnegative regulation of T cell activation
D0005102molecular_functionsignaling receptor binding
D0050868biological_processnegative regulation of T cell activation
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
BTYR207-HIS213
CTYR198-HIS204

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN32
AASN101
DASN32
DASN101

223790

PDB entries from 2024-08-14

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