8JEN
Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| I | 0005102 | molecular_function | signaling receptor binding |
| I | 0050868 | biological_process | negative regulation of T cell activation |
| J | 0005102 | molecular_function | signaling receptor binding |
| J | 0050868 | biological_process | negative regulation of T cell activation |
| M | 0005102 | molecular_function | signaling receptor binding |
| M | 0050868 | biological_process | negative regulation of T cell activation |
| P | 0005102 | molecular_function | signaling receptor binding |
| P | 0050868 | biological_process | negative regulation of T cell activation |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| A | TYR200-HIS206 | |
| B | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Region: {"description":"Homodimerization"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |






