8J9H

Cryo-EM structure of Euglena gracilis respiratory complex I, deactive state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1A	0016020	cellular_component	membrane
1A	0016491	molecular_function	oxidoreductase activity
1A	0042773	biological_process	ATP synthesis coupled electron transport
1A	0051536	molecular_function	iron-sulfur cluster binding
A5	0022904	biological_process	respiratory electron transport chain
AB	0006633	biological_process	fatty acid biosynthetic process
AC	0006633	biological_process	fatty acid biosynthetic process
AL	0016020	cellular_component	membrane
AL	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B7	0005739	cellular_component	mitochondrion
E2	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
E2	0006094	biological_process	gluconeogenesis
E2	0017076	molecular_function	purine nucleotide binding
E3	0016491	molecular_function	oxidoreductase activity
E5	0016491	molecular_function	oxidoreductase activity
EB	0005507	molecular_function	copper ion binding
EB	0005758	cellular_component	mitochondrial intermembrane space
EB	0016531	molecular_function	copper chaperone activity
EC	0006633	biological_process	fatty acid biosynthetic process
FX	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
N1	0016020	cellular_component	membrane
N4	0005739	cellular_component	mitochondrion
N4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N4	0016020	cellular_component	membrane
N4	0031966	cellular_component	mitochondrial membrane
N4	0042773	biological_process	ATP synthesis coupled electron transport
N4	0070469	cellular_component	respirasome
N4	1902600	biological_process	proton transmembrane transport
N5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N5	0042773	biological_process	ATP synthesis coupled electron transport
S2	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S2	0048038	molecular_function	quinone binding
S2	0051287	molecular_function	NAD binding
S3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S7	0048038	molecular_function	quinone binding
S7	0051536	molecular_function	iron-sulfur cluster binding
S7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
S8	0016020	cellular_component	membrane
S8	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
S8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
V1	0010181	molecular_function	FMN binding
V1	0051287	molecular_function	NAD binding
V1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
V2	0016491	molecular_function	oxidoreductase activity

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDVVEVVMAL

Chain	Residue	Details
AC	ASP86-LEU101
AB	ASP86-LEU101

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site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPLqvr..TGSGgHhshS

Chain	Residue	Details
B2	LYS24-SER39

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site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiTCQlCEvTCP

Chain	Residue	Details
S8	CYS104-PRO115
S8	CYS143-PRO154

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site_id	PS00503
Number of Residues	10
Details	PECTINESTERASE_2 Pectinesterase signature 2. ViGTLDIVFG

Chain	Residue	Details
S2	VAL382-GLY391

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site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLmEmK

Chain	Residue	Details
S2	LEU49-LYS60

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site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREawDMFgvffvgHpdlRrML

Chain	Residue	Details
S3	GLU159-LEU180

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site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PhfCYnrnlpiaGnCRmC

Chain	Residue	Details
1A	PRO75-CYS92

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site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
1A	CYS142-GLN154

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site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. VEAGGLST

Chain	Residue	Details
A6	VAL314-THR321

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site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DglFSicemeCMGaCvhAP

Chain	Residue	Details
V2	ASP133-PRO151

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