8ILH

The crystal structure of dG(Se-Sp)-DNA:Pol X product binary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006259	biological_process	DNA metabolic process
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0006303	biological_process	double-strand break repair via nonhomologous end joining
A	0009059	biological_process	macromolecule biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0071897	biological_process	DNA biosynthetic process
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0006259	biological_process	DNA metabolic process
B	0006281	biological_process	DNA repair
B	0006284	biological_process	base-excision repair
B	0006303	biological_process	double-strand break repair via nonhomologous end joining
B	0009059	biological_process	macromolecule biosynthetic process
B	0016779	molecular_function	nucleotidyltransferase activity
B	0044423	cellular_component	virion component
B	0046872	molecular_function	metal ion binding
B	0071897	biological_process	DNA biosynthetic process
C	0003677	molecular_function	DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0006259	biological_process	DNA metabolic process
C	0006281	biological_process	DNA repair
C	0006284	biological_process	base-excision repair
C	0006303	biological_process	double-strand break repair via nonhomologous end joining
C	0009059	biological_process	macromolecule biosynthetic process
C	0016779	molecular_function	nucleotidyltransferase activity
C	0044423	cellular_component	virion component
C	0046872	molecular_function	metal ion binding
C	0071897	biological_process	DNA biosynthetic process
D	0003677	molecular_function	DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0006259	biological_process	DNA metabolic process
D	0006281	biological_process	DNA repair
D	0006284	biological_process	base-excision repair
D	0006303	biological_process	double-strand break repair via nonhomologous end joining
D	0009059	biological_process	macromolecule biosynthetic process
D	0016779	molecular_function	nucleotidyltransferase activity
D	0044423	cellular_component	virion component
D	0046872	molecular_function	metal ion binding
D	0071897	biological_process	DNA biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00522
Number of Residues	20
Details	DNA_POLYMERASE_X DNA polymerase family X signature. GSLrREekmLnDVDLLIivP

Chain	Residue	Details
A	GLY38-PRO57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:11685239, ECO:0000305|PubMed:28245220

Chain	Residue	Details
A	ASP49
D	ASP49
D	ASP51
D	ASP100
A	ASP51
A	ASP100
B	ASP49
B	ASP51
B	ASP100
C	ASP49
C	ASP51
C	ASP100

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site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Stabilizes dGTP in a syn confromation to overcome the Watson-Crick base pairing constraint => ECO:0000269|PubMed:24617852

Chain	Residue	Details
A	HIS115
B	HIS115
C	HIS115
D	HIS115

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