8HUE
Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P
Functional Information from PROSITE/UniProt
| site_id | PS00247 |
| Number of Residues | 24 |
| Details | HBGF_FGF HBGF/FGF family signature. GrLlAskivtd.ECfFfErlesnnY |
| Chain | Residue | Details |
| A | GLY89-TYR112 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN36 | |
| B | ASN36 | |
| C | ASN36 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | SITE: Important for interaction with integrin => ECO:0000269|PubMed:28302677 |
| Chain | Residue | Details |
| A | LYS128 | |
| A | ARG129 | |
| A | LYS134 | |
| B | LYS128 | |
| B | ARG129 | |
| B | LYS134 | |
| C | LYS128 | |
| C | ARG129 | |
| C | LYS134 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphotyrosine; by TEC => ECO:0000269|PubMed:20230531 |
| Chain | Residue | Details |
| A | TYR82 | |
| B | TYR82 | |
| C | TYR82 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| A | LYS95 | |
| B | LYS95 | |
| C | LYS95 |
