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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8HTG

Crystal structure of Golf in complex with GTP-gamma S and Mg

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001664molecular_functionG protein-coupled receptor binding
A0001669cellular_componentacrosomal vesicle
A0001975biological_processresponse to amphetamine
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005834cellular_componentheterotrimeric G-protein complex
A0005886cellular_componentplasma membrane
A0005929cellular_componentcilium
A0007165biological_processsignal transduction
A0007186biological_processG protein-coupled receptor signaling pathway
A0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
A0007190biological_processactivation of adenylate cyclase activity
A0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
A0007606biological_processsensory perception of chemical stimulus
A0007608biological_processsensory perception of smell
A0016787molecular_functionhydrolase activity
A0019001molecular_functionguanyl nucleotide binding
A0031000biological_processresponse to caffeine
A0031683molecular_functionG-protein beta/gamma-subunit complex binding
A0046872molecular_functionmetal ion binding
A0090651cellular_componentapical cytoplasm
A0097225cellular_componentsperm midpiece
A0097538cellular_componentciliary necklace
A1900452biological_processregulation of long-term synaptic depression
A1900454biological_processpositive regulation of long-term synaptic depression
A1903351biological_processcellular response to dopamine
B0000166molecular_functionnucleotide binding
B0001664molecular_functionG protein-coupled receptor binding
B0001669cellular_componentacrosomal vesicle
B0001975biological_processresponse to amphetamine
B0003924molecular_functionGTPase activity
B0003925molecular_functionG protein activity
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005834cellular_componentheterotrimeric G-protein complex
B0005886cellular_componentplasma membrane
B0005929cellular_componentcilium
B0007165biological_processsignal transduction
B0007186biological_processG protein-coupled receptor signaling pathway
B0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
B0007190biological_processactivation of adenylate cyclase activity
B0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
B0007606biological_processsensory perception of chemical stimulus
B0007608biological_processsensory perception of smell
B0016787molecular_functionhydrolase activity
B0019001molecular_functionguanyl nucleotide binding
B0031000biological_processresponse to caffeine
B0031683molecular_functionG-protein beta/gamma-subunit complex binding
B0046872molecular_functionmetal ion binding
B0090651cellular_componentapical cytoplasm
B0097225cellular_componentsperm midpiece
B0097538cellular_componentciliary necklace
B1900452biological_processregulation of long-term synaptic depression
B1900454biological_processpositive regulation of long-term synaptic depression
B1903351biological_processcellular response to dopamine
C0000166molecular_functionnucleotide binding
C0001664molecular_functionG protein-coupled receptor binding
C0001669cellular_componentacrosomal vesicle
C0001975biological_processresponse to amphetamine
C0003924molecular_functionGTPase activity
C0003925molecular_functionG protein activity
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005834cellular_componentheterotrimeric G-protein complex
C0005886cellular_componentplasma membrane
C0005929cellular_componentcilium
C0007165biological_processsignal transduction
C0007186biological_processG protein-coupled receptor signaling pathway
C0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
C0007190biological_processactivation of adenylate cyclase activity
C0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
C0007606biological_processsensory perception of chemical stimulus
C0007608biological_processsensory perception of smell
C0016787molecular_functionhydrolase activity
C0019001molecular_functionguanyl nucleotide binding
C0031000biological_processresponse to caffeine
C0031683molecular_functionG-protein beta/gamma-subunit complex binding
C0046872molecular_functionmetal ion binding
C0090651cellular_componentapical cytoplasm
C0097225cellular_componentsperm midpiece
C0097538cellular_componentciliary necklace
C1900452biological_processregulation of long-term synaptic depression
C1900454biological_processpositive regulation of long-term synaptic depression
C1903351biological_processcellular response to dopamine
D0000166molecular_functionnucleotide binding
D0001664molecular_functionG protein-coupled receptor binding
D0001669cellular_componentacrosomal vesicle
D0001975biological_processresponse to amphetamine
D0003924molecular_functionGTPase activity
D0003925molecular_functionG protein activity
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005834cellular_componentheterotrimeric G-protein complex
D0005886cellular_componentplasma membrane
D0005929cellular_componentcilium
D0007165biological_processsignal transduction
D0007186biological_processG protein-coupled receptor signaling pathway
D0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
D0007190biological_processactivation of adenylate cyclase activity
D0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
D0007606biological_processsensory perception of chemical stimulus
D0007608biological_processsensory perception of smell
D0016787molecular_functionhydrolase activity
D0019001molecular_functionguanyl nucleotide binding
D0031000biological_processresponse to caffeine
D0031683molecular_functionG-protein beta/gamma-subunit complex binding
D0046872molecular_functionmetal ion binding
D0090651cellular_componentapical cytoplasm
D0097225cellular_componentsperm midpiece
D0097538cellular_componentciliary necklace
D1900452biological_processregulation of long-term synaptic depression
D1900454biological_processpositive regulation of long-term synaptic depression
D1903351biological_processcellular response to dopamine
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues52
DetailsRegion: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01230","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues32
DetailsRegion: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01230","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues36
DetailsRegion: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01230","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues28
DetailsRegion: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01230","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues20
DetailsRegion: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01230","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues48
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38062020","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"8HTG","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"38062020","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HTG","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues4
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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