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8HTG

Crystal structure of Golf in complex with GTP-gamma S and Mg

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001664molecular_functionG protein-coupled receptor binding
A0001975biological_processresponse to amphetamine
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005834cellular_componentheterotrimeric G-protein complex
A0005886cellular_componentplasma membrane
A0007165biological_processsignal transduction
A0007186biological_processG protein-coupled receptor signaling pathway
A0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
A0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
A0007606biological_processsensory perception of chemical stimulus
A0007608biological_processsensory perception of smell
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0019001molecular_functionguanyl nucleotide binding
A0031000biological_processresponse to caffeine
A0031683molecular_functionG-protein beta/gamma-subunit complex binding
A0046872molecular_functionmetal ion binding
B0000166molecular_functionnucleotide binding
B0001664molecular_functionG protein-coupled receptor binding
B0001975biological_processresponse to amphetamine
B0003924molecular_functionGTPase activity
B0003925molecular_functionG protein activity
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005834cellular_componentheterotrimeric G-protein complex
B0005886cellular_componentplasma membrane
B0007165biological_processsignal transduction
B0007186biological_processG protein-coupled receptor signaling pathway
B0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
B0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
B0007606biological_processsensory perception of chemical stimulus
B0007608biological_processsensory perception of smell
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0019001molecular_functionguanyl nucleotide binding
B0031000biological_processresponse to caffeine
B0031683molecular_functionG-protein beta/gamma-subunit complex binding
B0046872molecular_functionmetal ion binding
C0000166molecular_functionnucleotide binding
C0001664molecular_functionG protein-coupled receptor binding
C0001975biological_processresponse to amphetamine
C0003924molecular_functionGTPase activity
C0003925molecular_functionG protein activity
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005834cellular_componentheterotrimeric G-protein complex
C0005886cellular_componentplasma membrane
C0007165biological_processsignal transduction
C0007186biological_processG protein-coupled receptor signaling pathway
C0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
C0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
C0007606biological_processsensory perception of chemical stimulus
C0007608biological_processsensory perception of smell
C0016020cellular_componentmembrane
C0016787molecular_functionhydrolase activity
C0019001molecular_functionguanyl nucleotide binding
C0031000biological_processresponse to caffeine
C0031683molecular_functionG-protein beta/gamma-subunit complex binding
C0046872molecular_functionmetal ion binding
D0000166molecular_functionnucleotide binding
D0001664molecular_functionG protein-coupled receptor binding
D0001975biological_processresponse to amphetamine
D0003924molecular_functionGTPase activity
D0003925molecular_functionG protein activity
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005834cellular_componentheterotrimeric G-protein complex
D0005886cellular_componentplasma membrane
D0007165biological_processsignal transduction
D0007186biological_processG protein-coupled receptor signaling pathway
D0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
D0007191biological_processadenylate cyclase-activating dopamine receptor signaling pathway
D0007606biological_processsensory perception of chemical stimulus
D0007608biological_processsensory perception of smell
D0016020cellular_componentmembrane
D0016787molecular_functionhydrolase activity
D0019001molecular_functionguanyl nucleotide binding
D0031000biological_processresponse to caffeine
D0031683molecular_functionG-protein beta/gamma-subunit complex binding
D0046872molecular_functionmetal ion binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues48
DetailsBINDING: BINDING => ECO:0000305|PubMed:38062020, ECO:0007744|PDB:8HTG
ChainResidueDetails
AGLU52
ALYS280
AASP282
AALA353
BGLU52
BSER53
BGLY54
BLYS55
BTHR57
BLEU185
BARG186
ASER53
BGLY213
BASN279
BLYS280
BASP282
BALA353
CGLU52
CSER53
CGLY54
CLYS55
CTHR57
AGLY54
CLEU185
CARG186
CGLY213
CASN279
CLYS280
CASP282
CALA353
DGLU52
DSER53
DGLY54
ALYS55
DLYS55
DTHR57
DLEU185
DARG186
DGLY213
DASN279
DLYS280
DASP282
DALA353
ATHR57
ALEU185
AARG186
AGLY213
AASN279

site_idSWS_FT_FI2
Number of Residues12
DetailsBINDING: BINDING => ECO:0000269|PubMed:38062020, ECO:0007744|PDB:8HTG
ChainResidueDetails
ASER56
DSER56
DTHR191
DASP210
ATHR191
AASP210
BSER56
BTHR191
BASP210
CSER56
CTHR191
CASP210

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:21183079
ChainResidueDetails
ATHR178
BTHR178
CTHR178
DTHR178

site_idSWS_FT_FI4
Number of Residues4
DetailsLIPID: N-palmitoyl glycine => ECO:0000250|UniProtKB:P04896
ChainResidueDetails
AGLY2
BGLY2
CGLY2
DGLY2

site_idSWS_FT_FI5
Number of Residues4
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:P04896
ChainResidueDetails
ASER3
BSER3
CSER3
DSER3

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PDB entries from 2025-06-04

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