8G46

Cryo-EM structure of DDB1deltaB-DDA1-DCAF16-BRD4(BD2)-MMH2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0005634	cellular_component	nucleus
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0016567	biological_process	protein ubiquitination
B	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex
E	0000209	biological_process	protein polyubiquitination
E	0005515	molecular_function	protein binding
E	0005654	cellular_component	nucleoplasm
E	0016567	biological_process	protein ubiquitination
E	0032434	biological_process	regulation of proteasomal ubiquitin-dependent protein catabolic process
E	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
E	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
E	ALA2

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
E	SER33

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
E	SER95

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS1121

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