8FYD

Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex bent CRISPR repeat conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004527	molecular_function	exonuclease activity
A	0005829	cellular_component	cytosol
A	0008408	molecular_function	3'-5' exonuclease activity
A	0045004	biological_process	DNA replication proofreading
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004520	molecular_function	DNA endonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0043571	biological_process	maintenance of CRISPR repeat elements
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004520	molecular_function	DNA endonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0043571	biological_process	maintenance of CRISPR repeat elements
C	0046872	molecular_function	metal ion binding
C	0051607	biological_process	defense response to virus
D	0003676	molecular_function	nucleic acid binding
D	0004527	molecular_function	exonuclease activity
D	0005829	cellular_component	cytosol
D	0008408	molecular_function	3'-5' exonuclease activity
D	0045004	biological_process	DNA replication proofreading
E	0003676	molecular_function	nucleic acid binding
E	0003677	molecular_function	DNA binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004520	molecular_function	DNA endonuclease activity
E	0016787	molecular_function	hydrolase activity
E	0043571	biological_process	maintenance of CRISPR repeat elements
E	0046872	molecular_function	metal ion binding
E	0051607	biological_process	defense response to virus
F	0003676	molecular_function	nucleic acid binding
F	0003677	molecular_function	DNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0004520	molecular_function	DNA endonuclease activity
F	0016787	molecular_function	hydrolase activity
F	0043571	biological_process	maintenance of CRISPR repeat elements
F	0046872	molecular_function	metal ion binding
F	0051607	biological_process	defense response to virus