8FLJ

Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004520	molecular_function	DNA endonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0043571	biological_process	maintenance of CRISPR repeat elements
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004520	molecular_function	DNA endonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0042802	molecular_function	identical protein binding
B	0043571	biological_process	maintenance of CRISPR repeat elements
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004520	molecular_function	DNA endonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0042802	molecular_function	identical protein binding
C	0043571	biological_process	maintenance of CRISPR repeat elements
C	0046872	molecular_function	metal ion binding
C	0051607	biological_process	defense response to virus
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004520	molecular_function	DNA endonuclease activity
D	0016787	molecular_function	hydrolase activity
D	0042802	molecular_function	identical protein binding
D	0043571	biological_process	maintenance of CRISPR repeat elements
D	0046872	molecular_function	metal ion binding
D	0051607	biological_process	defense response to virus
E	0000976	molecular_function	transcription cis-regulatory region binding
E	0001216	molecular_function	DNA-binding transcription activator activity
E	0003677	molecular_function	DNA binding
E	0005829	cellular_component	cytosol
E	0006310	biological_process	DNA recombination
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006417	biological_process	regulation of translation
E	0030527	molecular_function	structural constituent of chromatin
E	0032993	cellular_component	protein-DNA complex
E	0045893	biological_process	positive regulation of DNA-templated transcription
F	0003677	molecular_function	DNA binding
F	0005694	cellular_component	chromosome
F	0005829	cellular_component	cytosol
F	0006310	biological_process	DNA recombination
F	0006351	biological_process	DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
F	0006417	biological_process	regulation of translation
F	0030527	molecular_function	structural constituent of chromatin
G	0000976	molecular_function	transcription cis-regulatory region binding
G	0001216	molecular_function	DNA-binding transcription activator activity
G	0003677	molecular_function	DNA binding
G	0005829	cellular_component	cytosol
G	0006310	biological_process	DNA recombination
G	0006351	biological_process	DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
G	0006417	biological_process	regulation of translation
G	0030527	molecular_function	structural constituent of chromatin
G	0032993	cellular_component	protein-DNA complex
G	0045893	biological_process	positive regulation of DNA-templated transcription
H	0003677	molecular_function	DNA binding
H	0005694	cellular_component	chromosome
H	0005829	cellular_component	cytosol
H	0006310	biological_process	DNA recombination
H	0006351	biological_process	DNA-templated transcription
H	0006355	biological_process	regulation of DNA-templated transcription
H	0006417	biological_process	regulation of translation
H	0030527	molecular_function	structural constituent of chromatin
M	0000166	molecular_function	nucleotide binding
M	0004386	molecular_function	helicase activity
M	0005524	molecular_function	ATP binding
M	0016787	molecular_function	hydrolase activity
M	0046872	molecular_function	metal ion binding
M	0051607	biological_process	defense response to virus
N	0000166	molecular_function	nucleotide binding
N	0004386	molecular_function	helicase activity
N	0005524	molecular_function	ATP binding
N	0016787	molecular_function	hydrolase activity
N	0046872	molecular_function	metal ion binding
N	0051607	biological_process	defense response to virus

Functional Information from PROSITE/UniProt

site_id	PS00045
Number of Residues	20
Details	HISTONE_LIKE Bacterial histone-like DNA-binding proteins signature. GFgnFdlrdKrqRp.GrNPkT

Chain	Residue	Details
E	GLY51-THR70
F	GLY49-THR68

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19523907","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GOD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	38
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	432
Details	Domain: {"description":"HD Cas3-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00974","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	6
Details	Motif: {"description":"DEAD box"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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