Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8FKP

Human nucleolar pre-60S ribosomal subunit (State A1)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
L6	0001824	biological_process	blastocyst development
L6	0002181	biological_process	cytoplasmic translation
L6	0003723	molecular_function	RNA binding
L6	0003735	molecular_function	structural constituent of ribosome
L6	0005515	molecular_function	protein binding
L6	0005634	cellular_component	nucleus
L6	0005730	cellular_component	nucleolus
L6	0005737	cellular_component	cytoplasm
L6	0005783	cellular_component	endoplasmic reticulum
L6	0005829	cellular_component	cytosol
L6	0005840	cellular_component	ribosome
L6	0006412	biological_process	translation
L6	0016020	cellular_component	membrane
L6	0022625	cellular_component	cytosolic large ribosomal subunit
L6	0022626	cellular_component	cytosolic ribosome
L6	0045202	cellular_component	synapse
L6	0060348	biological_process	bone development
L6	1990904	cellular_component	ribonucleoprotein complex
L7	0002181	biological_process	cytoplasmic translation
L7	0003723	molecular_function	RNA binding
L7	0003729	molecular_function	mRNA binding
L7	0003735	molecular_function	structural constituent of ribosome
L7	0005634	cellular_component	nucleus
L7	0005730	cellular_component	nucleolus
L7	0005737	cellular_component	cytoplasm
L7	0005829	cellular_component	cytosol
L7	0005840	cellular_component	ribosome
L7	0005925	cellular_component	focal adhesion
L7	0006412	biological_process	translation
L7	0006417	biological_process	regulation of translation
L7	0015934	cellular_component	large ribosomal subunit
L7	0016020	cellular_component	membrane
L7	0017148	biological_process	negative regulation of translation
L7	0022625	cellular_component	cytosolic large ribosomal subunit
L7	0022626	cellular_component	cytosolic ribosome
L7	0032496	biological_process	response to lipopolysaccharide
L7	0032819	biological_process	positive regulation of natural killer cell proliferation
L7	0042592	biological_process	homeostatic process
L7	0045202	cellular_component	synapse
L7	0048246	biological_process	macrophage chemotaxis
L7	0060425	biological_process	lung morphogenesis
L7	0071346	biological_process	cellular response to type II interferon
L7	0097452	cellular_component	GAIT complex
L7	1901194	biological_process	negative regulation of formation of translation preinitiation complex
L7	1990904	cellular_component	ribonucleoprotein complex
L8	0002181	biological_process	cytoplasmic translation
L8	0003723	molecular_function	RNA binding
L8	0003735	molecular_function	structural constituent of ribosome
L8	0005515	molecular_function	protein binding
L8	0005737	cellular_component	cytoplasm
L8	0005829	cellular_component	cytosol
L8	0005840	cellular_component	ribosome
L8	0006364	biological_process	rRNA processing
L8	0006412	biological_process	translation
L8	0014069	cellular_component	postsynaptic density
L8	0015934	cellular_component	large ribosomal subunit
L8	0016020	cellular_component	membrane
L8	0022625	cellular_component	cytosolic large ribosomal subunit
L8	0022626	cellular_component	cytosolic ribosome
L8	0042273	biological_process	ribosomal large subunit biogenesis
L8	0045296	molecular_function	cadherin binding
L8	0070062	cellular_component	extracellular exosome
L8	1990904	cellular_component	ribonucleoprotein complex
L9	0002181	biological_process	cytoplasmic translation
L9	0003723	molecular_function	RNA binding
L9	0003735	molecular_function	structural constituent of ribosome
L9	0005515	molecular_function	protein binding
L9	0005634	cellular_component	nucleus
L9	0005737	cellular_component	cytoplasm
L9	0005829	cellular_component	cytosol
L9	0005840	cellular_component	ribosome
L9	0006412	biological_process	translation
L9	0022625	cellular_component	cytosolic large ribosomal subunit
L9	0022626	cellular_component	cytosolic ribosome
L9	0044391	cellular_component	ribosomal subunit
L9	0045202	cellular_component	synapse
L9	0045296	molecular_function	cadherin binding
L9	1990904	cellular_component	ribonucleoprotein complex
LA	0002181	biological_process	cytoplasmic translation
LA	0003723	molecular_function	RNA binding
LA	0003735	molecular_function	structural constituent of ribosome
LA	0005515	molecular_function	protein binding
LA	0005634	cellular_component	nucleus
LA	0005737	cellular_component	cytoplasm
LA	0005829	cellular_component	cytosol
LA	0005840	cellular_component	ribosome
LA	0006412	biological_process	translation
LA	0015934	cellular_component	large ribosomal subunit
LA	0022625	cellular_component	cytosolic large ribosomal subunit
LA	0022626	cellular_component	cytosolic ribosome
LA	1990904	cellular_component	ribonucleoprotein complex
LB	0002181	biological_process	cytoplasmic translation
LB	0003723	molecular_function	RNA binding
LB	0003735	molecular_function	structural constituent of ribosome
LB	0005515	molecular_function	protein binding
LB	0005634	cellular_component	nucleus
LB	0005730	cellular_component	nucleolus
LB	0005737	cellular_component	cytoplasm
LB	0005783	cellular_component	endoplasmic reticulum
LB	0005791	cellular_component	rough endoplasmic reticulum
LB	0005829	cellular_component	cytosol
LB	0005840	cellular_component	ribosome
LB	0005925	cellular_component	focal adhesion
LB	0006412	biological_process	translation
LB	0016020	cellular_component	membrane
LB	0022625	cellular_component	cytosolic large ribosomal subunit
LB	0022626	cellular_component	cytosolic ribosome
LB	1990904	cellular_component	ribonucleoprotein complex
LC	0002181	biological_process	cytoplasmic translation
LC	0003723	molecular_function	RNA binding
LC	0003735	molecular_function	structural constituent of ribosome
LC	0005515	molecular_function	protein binding
LC	0005737	cellular_component	cytoplasm
LC	0005829	cellular_component	cytosol
LC	0005840	cellular_component	ribosome
LC	0006412	biological_process	translation
LC	0014069	cellular_component	postsynaptic density
LC	0016020	cellular_component	membrane
LC	0022625	cellular_component	cytosolic large ribosomal subunit
LC	0022626	cellular_component	cytosolic ribosome
LC	1990904	cellular_component	ribonucleoprotein complex
LE	0002181	biological_process	cytoplasmic translation
LE	0003723	molecular_function	RNA binding
LE	0003735	molecular_function	structural constituent of ribosome
LE	0005515	molecular_function	protein binding
LE	0005737	cellular_component	cytoplasm
LE	0005783	cellular_component	endoplasmic reticulum
LE	0005829	cellular_component	cytosol
LE	0005840	cellular_component	ribosome
LE	0006412	biological_process	translation
LE	0016020	cellular_component	membrane
LE	0022625	cellular_component	cytosolic large ribosomal subunit
LE	0022626	cellular_component	cytosolic ribosome
LE	0045202	cellular_component	synapse
LE	1990904	cellular_component	ribonucleoprotein complex
LG	0000122	biological_process	negative regulation of transcription by RNA polymerase II
LG	0001223	molecular_function	transcription coactivator binding
LG	0002181	biological_process	cytoplasmic translation
LG	0003723	molecular_function	RNA binding
LG	0003735	molecular_function	structural constituent of ribosome
LG	0005515	molecular_function	protein binding
LG	0005654	cellular_component	nucleoplasm
LG	0005730	cellular_component	nucleolus
LG	0005737	cellular_component	cytoplasm
LG	0005829	cellular_component	cytosol
LG	0005840	cellular_component	ribosome
LG	0005925	cellular_component	focal adhesion
LG	0006412	biological_process	translation
LG	0006610	biological_process	ribosomal protein import into nucleus
LG	0008284	biological_process	positive regulation of cell population proliferation
LG	0015934	cellular_component	large ribosomal subunit
LG	0016020	cellular_component	membrane
LG	0022625	cellular_component	cytosolic large ribosomal subunit
LG	0022626	cellular_component	cytosolic ribosome
LG	0031625	molecular_function	ubiquitin protein ligase binding
LG	0032986	biological_process	protein-DNA complex disassembly
LG	0032991	cellular_component	protein-containing complex
LG	0045202	cellular_component	synapse
LG	0050821	biological_process	protein stabilization
LG	0070062	cellular_component	extracellular exosome
LG	0070180	molecular_function	large ribosomal subunit rRNA binding
LG	0070314	biological_process	G1 to G0 transition
LG	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
LG	1903450	biological_process	regulation of G1 to G0 transition
LG	1990904	cellular_component	ribonucleoprotein complex
LG	1990948	molecular_function	ubiquitin ligase inhibitor activity
LG	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
LH	0002181	biological_process	cytoplasmic translation
LH	0003723	molecular_function	RNA binding
LH	0003735	molecular_function	structural constituent of ribosome
LH	0005515	molecular_function	protein binding
LH	0005634	cellular_component	nucleus
LH	0005730	cellular_component	nucleolus
LH	0005737	cellular_component	cytoplasm
LH	0005829	cellular_component	cytosol
LH	0005840	cellular_component	ribosome
LH	0006412	biological_process	translation
LH	0019843	molecular_function	rRNA binding
LH	0022625	cellular_component	cytosolic large ribosomal subunit
LH	0022626	cellular_component	cytosolic ribosome
LH	0045296	molecular_function	cadherin binding
LH	0070062	cellular_component	extracellular exosome
LH	1904841	molecular_function	TORC2 complex binding
LH	1990904	cellular_component	ribonucleoprotein complex
LI	0002181	biological_process	cytoplasmic translation
LI	0003723	molecular_function	RNA binding
LI	0003735	molecular_function	structural constituent of ribosome
LI	0005515	molecular_function	protein binding
LI	0005654	cellular_component	nucleoplasm
LI	0005730	cellular_component	nucleolus
LI	0005737	cellular_component	cytoplasm
LI	0005829	cellular_component	cytosol
LI	0005840	cellular_component	ribosome
LI	0006364	biological_process	rRNA processing
LI	0006412	biological_process	translation
LI	0015934	cellular_component	large ribosomal subunit
LI	0016020	cellular_component	membrane
LI	0022625	cellular_component	cytosolic large ribosomal subunit
LI	0022626	cellular_component	cytosolic ribosome
LI	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
LI	0034644	biological_process	cellular response to UV
LI	0042273	biological_process	ribosomal large subunit biogenesis
LI	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
LI	0045727	biological_process	positive regulation of translation
LI	0048027	molecular_function	mRNA 5'-UTR binding
LI	0070062	cellular_component	extracellular exosome
LI	0071480	biological_process	cellular response to gamma radiation
LI	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
LI	1904803	biological_process	regulation of translation involved in cellular response to UV
LI	1990904	cellular_component	ribonucleoprotein complex
LK	0002181	biological_process	cytoplasmic translation
LK	0003723	molecular_function	RNA binding
LK	0003735	molecular_function	structural constituent of ribosome
LK	0005515	molecular_function	protein binding
LK	0005654	cellular_component	nucleoplasm
LK	0005737	cellular_component	cytoplasm
LK	0005783	cellular_component	endoplasmic reticulum
LK	0005829	cellular_component	cytosol
LK	0005840	cellular_component	ribosome
LK	0006412	biological_process	translation
LK	0015934	cellular_component	large ribosomal subunit
LK	0016020	cellular_component	membrane
LK	0022625	cellular_component	cytosolic large ribosomal subunit
LK	0022626	cellular_component	cytosolic ribosome
LK	0045202	cellular_component	synapse
LK	1990904	cellular_component	ribonucleoprotein complex
LN	0002181	biological_process	cytoplasmic translation
LN	0003723	molecular_function	RNA binding
LN	0003735	molecular_function	structural constituent of ribosome
LN	0005515	molecular_function	protein binding
LN	0005634	cellular_component	nucleus
LN	0005730	cellular_component	nucleolus
LN	0005737	cellular_component	cytoplasm
LN	0005829	cellular_component	cytosol
LN	0005840	cellular_component	ribosome
LN	0005925	cellular_component	focal adhesion
LN	0006412	biological_process	translation
LN	0022625	cellular_component	cytosolic large ribosomal subunit
LN	0022626	cellular_component	cytosolic ribosome
LN	0032991	cellular_component	protein-containing complex
LN	0070062	cellular_component	extracellular exosome
LN	0071353	biological_process	cellular response to interleukin-4
LN	1990904	cellular_component	ribonucleoprotein complex
LQ	0002181	biological_process	cytoplasmic translation
LQ	0003723	molecular_function	RNA binding
LQ	0003735	molecular_function	structural constituent of ribosome
LQ	0005737	cellular_component	cytoplasm
LQ	0005829	cellular_component	cytosol
LQ	0005840	cellular_component	ribosome
LQ	0006412	biological_process	translation
LQ	0016020	cellular_component	membrane
LQ	0022625	cellular_component	cytosolic large ribosomal subunit
LQ	0022626	cellular_component	cytosolic ribosome
LQ	1990904	cellular_component	ribonucleoprotein complex
LS	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LS	0002181	biological_process	cytoplasmic translation
LS	0003723	molecular_function	RNA binding
LS	0003729	molecular_function	mRNA binding
LS	0003735	molecular_function	structural constituent of ribosome
LS	0005730	cellular_component	nucleolus
LS	0005737	cellular_component	cytoplasm
LS	0005829	cellular_component	cytosol
LS	0005840	cellular_component	ribosome
LS	0006412	biological_process	translation
LS	0015934	cellular_component	large ribosomal subunit
LS	0016020	cellular_component	membrane
LS	0022625	cellular_component	cytosolic large ribosomal subunit
LS	0022626	cellular_component	cytosolic ribosome
LS	1990904	cellular_component	ribonucleoprotein complex
LT	0000049	molecular_function	tRNA binding
LT	0002181	biological_process	cytoplasmic translation
LT	0003723	molecular_function	RNA binding
LT	0003735	molecular_function	structural constituent of ribosome
LT	0005515	molecular_function	protein binding
LT	0005737	cellular_component	cytoplasm
LT	0005829	cellular_component	cytosol
LT	0005840	cellular_component	ribosome
LT	0006364	biological_process	rRNA processing
LT	0006412	biological_process	translation
LT	0016020	cellular_component	membrane
LT	0022625	cellular_component	cytosolic large ribosomal subunit
LT	0022626	cellular_component	cytosolic ribosome
LT	0042273	biological_process	ribosomal large subunit biogenesis
LT	0045202	cellular_component	synapse
LT	0070062	cellular_component	extracellular exosome
LT	1990904	cellular_component	ribonucleoprotein complex
LU	0002181	biological_process	cytoplasmic translation
LU	0003723	molecular_function	RNA binding
LU	0003735	molecular_function	structural constituent of ribosome
LU	0005515	molecular_function	protein binding
LU	0005730	cellular_component	nucleolus
LU	0005737	cellular_component	cytoplasm
LU	0005829	cellular_component	cytosol
LU	0005840	cellular_component	ribosome
LU	0006412	biological_process	translation
LU	0016020	cellular_component	membrane
LU	0022625	cellular_component	cytosolic large ribosomal subunit
LU	0022626	cellular_component	cytosolic ribosome
LU	0045202	cellular_component	synapse
LU	1990904	cellular_component	ribonucleoprotein complex
LW	0002181	biological_process	cytoplasmic translation
LW	0003723	molecular_function	RNA binding
LW	0003735	molecular_function	structural constituent of ribosome
LW	0005737	cellular_component	cytoplasm
LW	0005829	cellular_component	cytosol
LW	0005840	cellular_component	ribosome
LW	0006412	biological_process	translation
LW	0008270	molecular_function	zinc ion binding
LW	0019843	molecular_function	rRNA binding
LW	0022625	cellular_component	cytosolic large ribosomal subunit
LW	0022626	cellular_component	cytosolic ribosome
LW	0045202	cellular_component	synapse
LW	0046872	molecular_function	metal ion binding
LW	0097371	molecular_function	MDM2/MDM4 family protein binding
LW	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
LW	1990904	cellular_component	ribonucleoprotein complex
LW	1990948	molecular_function	ubiquitin ligase inhibitor activity
NB	0000166	molecular_function	nucleotide binding
NB	0003723	molecular_function	RNA binding
NB	0005515	molecular_function	protein binding
NB	0005525	molecular_function	GTP binding
NB	0005615	cellular_component	extracellular space
NB	0005634	cellular_component	nucleus
NB	0005654	cellular_component	nucleoplasm
NB	0005694	cellular_component	chromosome
NB	0005730	cellular_component	nucleolus
NB	0016020	cellular_component	membrane
NB	0016604	cellular_component	nuclear body
NB	0017145	biological_process	stem cell division
NB	0019827	biological_process	stem cell population maintenance
NB	0030496	cellular_component	midbody
NB	0032206	biological_process	positive regulation of telomere maintenance
NB	0033235	biological_process	positive regulation of protein sumoylation
NB	0042127	biological_process	regulation of cell population proliferation
NB	0048027	molecular_function	mRNA 5'-UTR binding
NB	1902895	biological_process	positive regulation of miRNA transcription
NB	1904816	biological_process	positive regulation of protein localization to chromosome, telomeric region
NE	0001652	cellular_component	granular component
NE	0003677	molecular_function	DNA binding
NE	0003723	molecular_function	RNA binding
NE	0005515	molecular_function	protein binding
NE	0005654	cellular_component	nucleoplasm
NE	0005694	cellular_component	chromosome
NE	0005730	cellular_component	nucleolus
NE	0042254	biological_process	ribosome biogenesis
NE	0042273	biological_process	ribosomal large subunit biogenesis
NE	0042274	biological_process	ribosomal small subunit biogenesis
NE	0140693	molecular_function	molecular condensate scaffold activity
NG	0000460	biological_process	maturation of 5.8S rRNA
NG	0000470	biological_process	maturation of LSU-rRNA
NG	0006364	biological_process	rRNA processing
NG	0030687	cellular_component	preribosome, large subunit precursor
NM	0000460	biological_process	maturation of 5.8S rRNA
NM	0000470	biological_process	maturation of LSU-rRNA
NM	0003723	molecular_function	RNA binding
NM	0005515	molecular_function	protein binding
NM	0005730	cellular_component	nucleolus
NM	0030687	cellular_component	preribosome, large subunit precursor
NN	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NN	0003723	molecular_function	RNA binding
NN	0005634	cellular_component	nucleus
NN	0005730	cellular_component	nucleolus
NN	0006364	biological_process	rRNA processing
NN	0019843	molecular_function	rRNA binding
NN	0030687	cellular_component	preribosome, large subunit precursor
NO	0003723	molecular_function	RNA binding
NO	0005515	molecular_function	protein binding
NO	0005634	cellular_component	nucleus
NO	0005694	cellular_component	chromosome
NO	0005730	cellular_component	nucleolus
NO	0006364	biological_process	rRNA processing
NO	0030688	cellular_component	preribosome, small subunit precursor
NQ	0000176	cellular_component	nuclear exosome (RNase complex)
NQ	0001825	biological_process	blastocyst formation
NQ	0005515	molecular_function	protein binding
NQ	0005634	cellular_component	nucleus
NQ	0005654	cellular_component	nucleoplasm
NQ	0005730	cellular_component	nucleolus
NQ	0006364	biological_process	rRNA processing
NQ	0016070	biological_process	RNA metabolic process
NQ	0030687	cellular_component	preribosome, large subunit precursor
NQ	0042273	biological_process	ribosomal large subunit biogenesis
NS	0000460	biological_process	maturation of 5.8S rRNA
NS	0000470	biological_process	maturation of LSU-rRNA
NS	0003723	molecular_function	RNA binding
NS	0005515	molecular_function	protein binding
NS	0005730	cellular_component	nucleolus
NS	0006364	biological_process	rRNA processing
NS	0019843	molecular_function	rRNA binding
NS	0030687	cellular_component	preribosome, large subunit precursor
NS	0042134	molecular_function	rRNA primary transcript binding
NS	0042254	biological_process	ribosome biogenesis
SA	0002181	biological_process	cytoplasmic translation
SA	0003723	molecular_function	RNA binding
SA	0003735	molecular_function	structural constituent of ribosome
SA	0005515	molecular_function	protein binding
SA	0005634	cellular_component	nucleus
SA	0005730	cellular_component	nucleolus
SA	0005737	cellular_component	cytoplasm
SA	0005783	cellular_component	endoplasmic reticulum
SA	0005791	cellular_component	rough endoplasmic reticulum
SA	0005829	cellular_component	cytosol
SA	0005840	cellular_component	ribosome
SA	0005925	cellular_component	focal adhesion
SA	0006412	biological_process	translation
SA	0016020	cellular_component	membrane
SA	0016604	cellular_component	nuclear body
SA	0022625	cellular_component	cytosolic large ribosomal subunit
SA	0022626	cellular_component	cytosolic ribosome
SA	0070062	cellular_component	extracellular exosome
SA	1990904	cellular_component	ribonucleoprotein complex
SC	0002181	biological_process	cytoplasmic translation
SC	0003677	molecular_function	DNA binding
SC	0003723	molecular_function	RNA binding
SC	0003735	molecular_function	structural constituent of ribosome
SC	0005515	molecular_function	protein binding
SC	0005634	cellular_component	nucleus
SC	0005737	cellular_component	cytoplasm
SC	0005791	cellular_component	rough endoplasmic reticulum
SC	0005829	cellular_component	cytosol
SC	0005840	cellular_component	ribosome
SC	0005925	cellular_component	focal adhesion
SC	0006355	biological_process	regulation of DNA-templated transcription
SC	0006412	biological_process	translation
SC	0014069	cellular_component	postsynaptic density
SC	0015934	cellular_component	large ribosomal subunit
SC	0016020	cellular_component	membrane
SC	0022625	cellular_component	cytosolic large ribosomal subunit
SC	0022626	cellular_component	cytosolic ribosome
SC	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
SC	0045202	cellular_component	synapse
SC	0045296	molecular_function	cadherin binding
SC	1990904	cellular_component	ribonucleoprotein complex
SD	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SD	0002181	biological_process	cytoplasmic translation
SD	0003677	molecular_function	DNA binding
SD	0003723	molecular_function	RNA binding
SD	0003729	molecular_function	mRNA binding
SD	0003735	molecular_function	structural constituent of ribosome
SD	0005515	molecular_function	protein binding
SD	0005634	cellular_component	nucleus
SD	0005730	cellular_component	nucleolus
SD	0005737	cellular_component	cytoplasm
SD	0005783	cellular_component	endoplasmic reticulum
SD	0005829	cellular_component	cytosol
SD	0005840	cellular_component	ribosome
SD	0005925	cellular_component	focal adhesion
SD	0006364	biological_process	rRNA processing
SD	0006412	biological_process	translation
SD	0014069	cellular_component	postsynaptic density
SD	0016020	cellular_component	membrane
SD	0022625	cellular_component	cytosolic large ribosomal subunit
SD	0022626	cellular_component	cytosolic ribosome
SD	0042273	biological_process	ribosomal large subunit biogenesis
SD	0042802	molecular_function	identical protein binding
SD	1990904	cellular_component	ribonucleoprotein complex
SE	0000470	biological_process	maturation of LSU-rRNA
SE	0002181	biological_process	cytoplasmic translation
SE	0003723	molecular_function	RNA binding
SE	0003735	molecular_function	structural constituent of ribosome
SE	0005515	molecular_function	protein binding
SE	0005634	cellular_component	nucleus
SE	0005730	cellular_component	nucleolus
SE	0005737	cellular_component	cytoplasm
SE	0005829	cellular_component	cytosol
SE	0005840	cellular_component	ribosome
SE	0005925	cellular_component	focal adhesion
SE	0006412	biological_process	translation
SE	0016020	cellular_component	membrane
SE	0022625	cellular_component	cytosolic large ribosomal subunit
SE	0022626	cellular_component	cytosolic ribosome
SE	0042254	biological_process	ribosome biogenesis
SE	0045202	cellular_component	synapse
SE	0045296	molecular_function	cadherin binding
SE	1990904	cellular_component	ribonucleoprotein complex
SH	0000794	cellular_component	condensed nuclear chromosome
SH	0003676	molecular_function	nucleic acid binding
SH	0003723	molecular_function	RNA binding
SH	0005515	molecular_function	protein binding
SH	0005654	cellular_component	nucleoplasm
SH	0005694	cellular_component	chromosome
SH	0005730	cellular_component	nucleolus
SH	0005737	cellular_component	cytoplasm
SH	0009303	biological_process	rRNA transcription
SH	0016072	biological_process	rRNA metabolic process
SH	0065003	biological_process	protein-containing complex assembly
SI	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SI	0001825	biological_process	blastocyst formation
SI	0003723	molecular_function	RNA binding
SI	0003735	molecular_function	structural constituent of ribosome
SI	0005515	molecular_function	protein binding
SI	0005730	cellular_component	nucleolus
SI	0005739	cellular_component	mitochondrion
SI	0005840	cellular_component	ribosome
SI	0022625	cellular_component	cytosolic large ribosomal subunit
SI	1990904	cellular_component	ribonucleoprotein complex
SJ	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SJ	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SJ	0001510	biological_process	RNA methylation
SJ	0003723	molecular_function	RNA binding
SJ	0005515	molecular_function	protein binding
SJ	0005634	cellular_component	nucleus
SJ	0005654	cellular_component	nucleoplasm
SJ	0005694	cellular_component	chromosome
SJ	0005730	cellular_component	nucleolus
SJ	0006364	biological_process	rRNA processing
SJ	0008168	molecular_function	methyltransferase activity
SJ	0008649	molecular_function	rRNA methyltransferase activity
SJ	0008650	molecular_function	rRNA (uridine-2'-O-)-methyltransferase activity
SJ	0016435	molecular_function	rRNA (guanine) methyltransferase activity
SJ	0016740	molecular_function	transferase activity
SJ	0030687	cellular_component	preribosome, large subunit precursor
SJ	0030688	cellular_component	preribosome, small subunit precursor
SJ	0031167	biological_process	rRNA methylation
SJ	0032259	biological_process	methylation
SJ	0042254	biological_process	ribosome biogenesis
SJ	0062105	molecular_function	RNA 2'-O-methyltransferase activity
SK	0000054	biological_process	ribosomal subunit export from nucleus
SK	0000460	biological_process	maturation of 5.8S rRNA
SK	0000470	biological_process	maturation of LSU-rRNA
SK	0003743	molecular_function	translation initiation factor activity
SK	0005515	molecular_function	protein binding
SK	0005634	cellular_component	nucleus
SK	0005638	cellular_component	lamin filament
SK	0005654	cellular_component	nucleoplasm
SK	0005730	cellular_component	nucleolus
SK	0005737	cellular_component	cytoplasm
SK	0005829	cellular_component	cytosol
SK	0005882	cellular_component	intermediate filament
SK	0006110	biological_process	regulation of glycolytic process
SK	0006412	biological_process	translation
SK	0006413	biological_process	translational initiation
SK	0032868	biological_process	response to insulin
SK	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
SK	0035278	biological_process	miRNA-mediated gene silencing by inhibition of translation
SK	0042254	biological_process	ribosome biogenesis
SK	0042256	biological_process	cytosolic ribosome assembly
SK	0042273	biological_process	ribosomal large subunit biogenesis
SK	0042304	biological_process	regulation of fatty acid biosynthetic process
SK	0043022	molecular_function	ribosome binding
SK	0043023	molecular_function	ribosomal large subunit binding
SK	0045202	cellular_component	synapse
SK	0045652	biological_process	regulation of megakaryocyte differentiation
SK	0045727	biological_process	positive regulation of translation
SK	0070062	cellular_component	extracellular exosome
SK	1902626	biological_process	assembly of large subunit precursor of preribosome
SK	2000377	biological_process	regulation of reactive oxygen species metabolic process
SL	0001649	biological_process	osteoblast differentiation
SL	0003723	molecular_function	RNA binding
SL	0003730	molecular_function	mRNA 3'-UTR binding
SL	0005515	molecular_function	protein binding
SL	0005694	cellular_component	chromosome
SL	0005730	cellular_component	nucleolus
SL	0005829	cellular_component	cytosol
SL	0005929	cellular_component	cilium
SL	0016020	cellular_component	membrane
SL	0032880	biological_process	regulation of protein localization
SL	0042981	biological_process	regulation of apoptotic process
SL	0045296	molecular_function	cadherin binding
SL	0048027	molecular_function	mRNA 5'-UTR binding
SL	2000772	biological_process	regulation of cellular senescence
SM	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SM	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SM	0003723	molecular_function	RNA binding
SM	0005515	molecular_function	protein binding
SM	0005634	cellular_component	nucleus
SM	0005654	cellular_component	nucleoplasm
SM	0005694	cellular_component	chromosome
SM	0005730	cellular_component	nucleolus
SM	0005829	cellular_component	cytosol
SM	0006364	biological_process	rRNA processing
SM	0008283	biological_process	cell population proliferation
SM	0016020	cellular_component	membrane
SM	0030687	cellular_component	preribosome, large subunit precursor
SM	0042254	biological_process	ribosome biogenesis
SM	0042273	biological_process	ribosomal large subunit biogenesis
SM	0043021	molecular_function	ribonucleoprotein complex binding
SM	0051726	biological_process	regulation of cell cycle
SM	0070545	cellular_component	PeBoW complex
SN	0003723	molecular_function	RNA binding
SN	0005515	molecular_function	protein binding
SN	0005694	cellular_component	chromosome
SN	0005730	cellular_component	nucleolus
SN	0006364	biological_process	rRNA processing
SN	0030687	cellular_component	preribosome, large subunit precursor
SN	0034399	cellular_component	nuclear periphery
SN	0042254	biological_process	ribosome biogenesis
SN	0042273	biological_process	ribosomal large subunit biogenesis
SO	0000027	biological_process	ribosomal large subunit assembly
SO	0003723	molecular_function	RNA binding
SO	0005515	molecular_function	protein binding
SO	0005694	cellular_component	chromosome
SO	0005730	cellular_component	nucleolus
SO	0006364	biological_process	rRNA processing
SO	0019843	molecular_function	rRNA binding
SO	0042254	biological_process	ribosome biogenesis
SR	0000166	molecular_function	nucleotide binding
SR	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SR	0001649	biological_process	osteoblast differentiation
SR	0003723	molecular_function	RNA binding
SR	0003924	molecular_function	GTPase activity
SR	0005515	molecular_function	protein binding
SR	0005525	molecular_function	GTP binding
SR	0005634	cellular_component	nucleus
SR	0005654	cellular_component	nucleoplasm
SR	0005730	cellular_component	nucleolus
SR	0005737	cellular_component	cytoplasm
SR	0005829	cellular_component	cytosol
SR	0008156	biological_process	negative regulation of DNA replication
SR	0008285	biological_process	negative regulation of cell population proliferation
SR	0010972	biological_process	negative regulation of G2/M transition of mitotic cell cycle
SR	0016020	cellular_component	membrane
SR	0022408	biological_process	negative regulation of cell-cell adhesion
SR	0030336	biological_process	negative regulation of cell migration
SR	0031397	biological_process	negative regulation of protein ubiquitination
SR	0031965	cellular_component	nuclear membrane
SR	0042254	biological_process	ribosome biogenesis
SR	0042273	biological_process	ribosomal large subunit biogenesis
SR	0048471	cellular_component	perinuclear region of cytoplasm
SR	0050821	biological_process	protein stabilization
SR	1990275	molecular_function	preribosome binding
SS	0000027	biological_process	ribosomal large subunit assembly
SS	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SS	0000460	biological_process	maturation of 5.8S rRNA
SS	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SS	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SS	0003723	molecular_function	RNA binding
SS	0005515	molecular_function	protein binding
SS	0005634	cellular_component	nucleus
SS	0005654	cellular_component	nucleoplasm
SS	0005694	cellular_component	chromosome
SS	0005730	cellular_component	nucleolus
SS	0006364	biological_process	rRNA processing
SS	0008283	biological_process	cell population proliferation
SS	0030687	cellular_component	preribosome, large subunit precursor
SS	0042254	biological_process	ribosome biogenesis
SS	0042273	biological_process	ribosomal large subunit biogenesis
SS	0043021	molecular_function	ribonucleoprotein complex binding
SS	0051726	biological_process	regulation of cell cycle
SS	0070545	cellular_component	PeBoW complex
SS	1901796	biological_process	regulation of signal transduction by p53 class mediator
SS	1990904	cellular_component	ribonucleoprotein complex
ST	0000027	biological_process	ribosomal large subunit assembly
ST	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ST	0000794	cellular_component	condensed nuclear chromosome
ST	0002244	biological_process	hematopoietic progenitor cell differentiation
ST	0003723	molecular_function	RNA binding
ST	0005515	molecular_function	protein binding
ST	0005634	cellular_component	nucleus
ST	0005654	cellular_component	nucleoplasm
ST	0005730	cellular_component	nucleolus
ST	0005783	cellular_component	endoplasmic reticulum
ST	0007080	biological_process	mitotic metaphase chromosome alignment
ST	0008097	molecular_function	5S rRNA binding
ST	0030687	cellular_component	preribosome, large subunit precursor
ST	0042254	biological_process	ribosome biogenesis
ST	0042273	biological_process	ribosomal large subunit biogenesis
ST	1901796	biological_process	regulation of signal transduction by p53 class mediator
ST	1902570	biological_process	protein localization to nucleolus
SV	0003735	molecular_function	structural constituent of ribosome
SV	0005515	molecular_function	protein binding
SV	0005654	cellular_component	nucleoplasm
SV	0005730	cellular_component	nucleolus
SV	0042254	biological_process	ribosome biogenesis
SV	0042273	biological_process	ribosomal large subunit biogenesis
SW	0000166	molecular_function	nucleotide binding
SW	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SW	0003676	molecular_function	nucleic acid binding
SW	0003723	molecular_function	RNA binding
SW	0003724	molecular_function	RNA helicase activity
SW	0004386	molecular_function	helicase activity
SW	0005515	molecular_function	protein binding
SW	0005524	molecular_function	ATP binding
SW	0005694	cellular_component	chromosome
SW	0005730	cellular_component	nucleolus
SW	0016020	cellular_component	membrane
SW	0016787	molecular_function	hydrolase activity
SW	0016887	molecular_function	ATP hydrolysis activity
SW	0071392	biological_process	cellular response to estradiol stimulus
SZ	0003723	molecular_function	RNA binding
SZ	0005654	cellular_component	nucleoplasm
SZ	0005730	cellular_component	nucleolus
SZ	0042273	biological_process	ribosomal large subunit biogenesis

Functional Information from PROSITE/UniProt

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
LI	ASP52-VAL70

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
SC	ASN182-LYS200

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
LE	GLY37-GLY62

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
LU	PRO52-LYS62

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
L9	ASP46-GLY69

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. SSCTTRkM

Chain	Residue	Details
SI	SER3-MET10

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
LA	ARG126-LEU150

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
LN	PHE211-ARG234

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
LK	LYS110-GLY141

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
LS	LYS43-VAL57

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
LQ	PHE20-GLY40

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSGsdDgSLRLWEV

Chain	Residue	Details
SS	LEU428-VAL442

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
SA	GLY15-VAL22

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VIDEADRiL

Chain	Residue	Details
SW	VAL331-LEU339

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
LG	ALA79-ILE105

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
LH	LYS134-VAL149

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
L7	VAL84-GLY107

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
SA	ASN116-HIS142

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FcSgpIyPGhGmmFvRnD

Chain	Residue	Details
SV	PHE8-ASP25

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
LW	GLY4-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
SE	CYS174-GLY191

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
L6	ARG71-GLY85

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
LT	GLY72-PRO93

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
LB	LYS49-MET66

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TIarLrLkKifSgVfvkvtpqnlkMLriVepYV

Chain	Residue	Details
SI	THR115-VAL147
SD	VAL108-ILE140

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	47
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by ZIPK/DAPK3","evidences":[{"source":"PubMed","id":"18995835","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P19253","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	16
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CR57","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	113
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	55
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P61314","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"25255805","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62717","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P62717","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	19
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P27659","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"33693809","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35674491","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P27659","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI27
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI28
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI29
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI30
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI31
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI33
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"O55142","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI34
Number of Residues	18
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI35
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P49166","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI36
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI38
Number of Residues	40
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

site_id	SWS_FT_FI39
Number of Residues	40
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

site_id	SWS_FT_FI40
Number of Residues	41
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

site_id	SWS_FT_FI41
Number of Residues	42
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

site_id	SWS_FT_FI42
Number of Residues	39
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

site_id	SWS_FT_FI43
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI44
Number of Residues	372
Details	Domain: {"description":"Brix","evidences":[{"source":"PROSITE-ProRule","id":"PRU00034","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI45
Number of Residues	17
Details	Region: {"description":"RNA-binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI46
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI47
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI48
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI49
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P50878","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI53
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P47911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI54
Number of Residues	11
Details	Repeat: {"description":"2"}

Chain

Residue

Details

site_id	SWS_FT_FI55
Number of Residues	11
Details	Repeat: {"description":"3"}

Chain

Residue

Details

site_id	SWS_FT_FI56
Number of Residues	11
Details	Repeat: {"description":"4"}

Chain

Residue

Details

site_id	SWS_FT_FI57
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P14148","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI58
Number of Residues	78
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI59
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine; by PRMT1 and PRMT8","evidences":[{"source":"PubMed","id":"26529540","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI60
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9D8M4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"O55135","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI62
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O55135","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI63
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by CK1","evidences":[{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12917340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21084295","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI64
Number of Residues	93
Details	Domain: {"description":"BRCT","evidences":[{"source":"HAMAP-Rule","id":"MF_03028","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI65
Number of Residues	31
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI66
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI67
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI68
Number of Residues	175
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI69
Number of Residues	28
Details	Motif: {"description":"Q motif"}

Chain

Residue

Details

site_id	SWS_FT_FI70
Number of Residues	3
Details	Motif: {"description":"DEAD box"}

Chain

Residue

Details

site_id	SWS_FT_FI71
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI72
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI73
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI74
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)