8DMK
Cryo-EM reveals the molecular basis of laminin polymerization and LN-lamininopathies
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CqCehNtcGEsC |
| Chain | Residue | Details |
| A | CYS297-CYS308 | |
| G | CYS305-CYS316 | |
| B | CYS298-CYS309 |
| site_id | PS01248 |
| Number of Residues | 35 |
| Details | EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cq.CehntcGesCdrCcpg.YhqqpwrpgtissgneC |
| Chain | Residue | Details |
| A | CYS297-CYS331 | |
| G | CYS305-CYS339 | |
| B | CYS298-CYS332 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 478 |
| Details | Domain: {"description":"Laminin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00466","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 118 |
| Details | Domain: {"description":"Laminin EGF-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02469","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
