8CZA
Crystal structure of the first bromodomain (BD1) of human BRDT bound to GXH-IV-075
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. SwpFqrpvDavklqlpDYYtiIknpMdlntIkkrlenky..Yakaseciedfnt.MfsNCylY |
| Chain | Residue | Details |
| A | SER49-TYR108 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22901802, ECO:0007744|PDB:4FLP |
| Chain | Residue | Details |
| A | ASN109 | |
| B | ASN109 | |
| C | ASN109 | |
| D | ASN109 | |
| E | ASN109 | |
| F | ASN109 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | SITE: Histone H4K5ac binding => ECO:0000250|UniProtKB:Q91Y44 |
| Chain | Residue | Details |
| A | ASN109 | |
| E | ASP114 | |
| F | ASN109 | |
| F | ASP114 | |
| A | ASP114 | |
| B | ASN109 | |
| B | ASP114 | |
| C | ASN109 | |
| C | ASP114 | |
| D | ASN109 | |
| D | ASP114 | |
| E | ASN109 |
