8CS9

Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005198	molecular_function	structural molecule activity
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005886	cellular_component	plasma membrane
A	0006887	biological_process	exocytosis
A	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
A	0007010	biological_process	cytoskeleton organization
A	0007165	biological_process	signal transduction
A	0008093	molecular_function	cytoskeletal anchor activity
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0014731	cellular_component	spectrin-associated cytoskeleton
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0016529	cellular_component	sarcoplasmic reticulum
A	0019899	molecular_function	enzyme binding
A	0019903	molecular_function	protein phosphatase binding
A	0030018	cellular_component	Z disc
A	0030507	molecular_function	spectrin binding
A	0030673	cellular_component	axolemma
A	0031430	cellular_component	M band
A	0031672	cellular_component	A band
A	0042383	cellular_component	sarcolemma
A	0043005	cellular_component	neuron projection
A	0044325	molecular_function	transmembrane transporter binding
A	0045199	biological_process	maintenance of epithelial cell apical/basal polarity
A	0045211	cellular_component	postsynaptic membrane
A	0048193	biological_process	Golgi vesicle transport
A	0051117	molecular_function	ATPase binding
A	0071944	cellular_component	cell periphery
A	0072659	biological_process	protein localization to plasma membrane
A	0170014	cellular_component	ankyrin-1 complex
K	0005886	cellular_component	plasma membrane
K	0008519	molecular_function	ammonium channel activity
K	0016020	cellular_component	membrane
K	0072488	biological_process	ammonium transmembrane transport
K	0097272	biological_process	ammonium homeostasis
K	0170014	cellular_component	ankyrin-1 complex
L	0005515	molecular_function	protein binding
L	0005886	cellular_component	plasma membrane
L	0006873	biological_process	intracellular monoatomic ion homeostasis
L	0008519	molecular_function	ammonium channel activity
L	0015200	molecular_function	methylammonium transmembrane transporter activity
L	0015670	biological_process	carbon dioxide transport
L	0015701	biological_process	bicarbonate transport
L	0016020	cellular_component	membrane
L	0022840	molecular_function	leak channel activity
L	0030506	molecular_function	ankyrin binding
L	0035378	biological_process	carbon dioxide transmembrane transport
L	0035379	molecular_function	carbon dioxide transmembrane transporter activity
L	0055085	biological_process	transmembrane transport
L	0072488	biological_process	ammonium transmembrane transport
L	0072489	biological_process	methylammonium transmembrane transport
L	0097272	biological_process	ammonium homeostasis
L	0170014	cellular_component	ankyrin-1 complex
P	0016020	cellular_component	membrane
Q	0005515	molecular_function	protein binding
Q	0005886	cellular_component	plasma membrane
Q	0006873	biological_process	intracellular monoatomic ion homeostasis
Q	0008519	molecular_function	ammonium channel activity
Q	0015200	molecular_function	methylammonium transmembrane transporter activity
Q	0015670	biological_process	carbon dioxide transport
Q	0015701	biological_process	bicarbonate transport
Q	0016020	cellular_component	membrane
Q	0022840	molecular_function	leak channel activity
Q	0030506	molecular_function	ankyrin binding
Q	0035378	biological_process	carbon dioxide transmembrane transport
Q	0035379	molecular_function	carbon dioxide transmembrane transporter activity
Q	0055085	biological_process	transmembrane transport
Q	0072488	biological_process	ammonium transmembrane transport
Q	0072489	biological_process	methylammonium transmembrane transport
Q	0097272	biological_process	ammonium homeostasis
Q	0170014	cellular_component	ankyrin-1 complex
R	0016020	cellular_component	membrane
S	0016020	cellular_component	membrane
T	0016020	cellular_component	membrane
V	0005452	molecular_function	solute:inorganic anion antiporter activity
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0005886	cellular_component	plasma membrane
V	0006811	biological_process	monoatomic ion transport
V	0006820	biological_process	monoatomic anion transport
V	0006821	biological_process	chloride transport
V	0006873	biological_process	intracellular monoatomic ion homeostasis
V	0008092	molecular_function	cytoskeletal protein binding
V	0008509	molecular_function	monoatomic anion transmembrane transporter activity
V	0009898	cellular_component	cytoplasmic side of plasma membrane
V	0015106	molecular_function	bicarbonate transmembrane transporter activity
V	0015108	molecular_function	chloride transmembrane transporter activity
V	0015297	molecular_function	antiporter activity
V	0015701	biological_process	bicarbonate transport
V	0016020	cellular_component	membrane
V	0016323	cellular_component	basolateral plasma membrane
V	0030018	cellular_component	Z disc
V	0030492	molecular_function	hemoglobin binding
V	0030506	molecular_function	ankyrin binding
V	0030863	cellular_component	cortical cytoskeleton
V	0042803	molecular_function	protein homodimerization activity
V	0043495	molecular_function	protein-membrane adaptor activity
V	0051453	biological_process	regulation of intracellular pH
V	0055085	biological_process	transmembrane transport
V	0070062	cellular_component	extracellular exosome
V	0072562	cellular_component	blood microparticle
V	0140900	molecular_function	chloride:bicarbonate antiporter activity
V	0170014	cellular_component	ankyrin-1 complex
V	1902476	biological_process	chloride transmembrane transport
X	0003810	molecular_function	protein-glutamine gamma-glutamyltransferase activity
X	0005200	molecular_function	structural constituent of cytoskeleton
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005856	cellular_component	cytoskeleton
X	0005886	cellular_component	plasma membrane
X	0007010	biological_process	cytoskeleton organization
X	0008360	biological_process	regulation of cell shape
X	0016020	cellular_component	membrane
X	0018149	biological_process	peptide cross-linking
X	0030863	cellular_component	cortical cytoskeleton
X	0043249	biological_process	erythrocyte maturation
X	0071944	cellular_component	cell periphery
X	0170014	cellular_component	ankyrin-1 complex
Y	0005452	molecular_function	solute:inorganic anion antiporter activity
Y	0005515	molecular_function	protein binding
Y	0005737	cellular_component	cytoplasm
Y	0005886	cellular_component	plasma membrane
Y	0006811	biological_process	monoatomic ion transport
Y	0006820	biological_process	monoatomic anion transport
Y	0006821	biological_process	chloride transport
Y	0006873	biological_process	intracellular monoatomic ion homeostasis
Y	0008092	molecular_function	cytoskeletal protein binding
Y	0008509	molecular_function	monoatomic anion transmembrane transporter activity
Y	0009898	cellular_component	cytoplasmic side of plasma membrane
Y	0015106	molecular_function	bicarbonate transmembrane transporter activity
Y	0015108	molecular_function	chloride transmembrane transporter activity
Y	0015297	molecular_function	antiporter activity
Y	0015701	biological_process	bicarbonate transport
Y	0016020	cellular_component	membrane
Y	0016323	cellular_component	basolateral plasma membrane
Y	0030018	cellular_component	Z disc
Y	0030492	molecular_function	hemoglobin binding
Y	0030506	molecular_function	ankyrin binding
Y	0030863	cellular_component	cortical cytoskeleton
Y	0042803	molecular_function	protein homodimerization activity
Y	0043495	molecular_function	protein-membrane adaptor activity
Y	0051453	biological_process	regulation of intracellular pH
Y	0055085	biological_process	transmembrane transport
Y	0070062	cellular_component	extracellular exosome
Y	0072562	cellular_component	blood microparticle
Y	0140900	molecular_function	chloride:bicarbonate antiporter activity
Y	0170014	cellular_component	ankyrin-1 complex
Y	1902476	biological_process	chloride transmembrane transport
Z	0005452	molecular_function	solute:inorganic anion antiporter activity
Z	0005515	molecular_function	protein binding
Z	0005737	cellular_component	cytoplasm
Z	0005886	cellular_component	plasma membrane
Z	0006811	biological_process	monoatomic ion transport
Z	0006820	biological_process	monoatomic anion transport
Z	0006821	biological_process	chloride transport
Z	0006873	biological_process	intracellular monoatomic ion homeostasis
Z	0008092	molecular_function	cytoskeletal protein binding
Z	0008509	molecular_function	monoatomic anion transmembrane transporter activity
Z	0009898	cellular_component	cytoplasmic side of plasma membrane
Z	0015106	molecular_function	bicarbonate transmembrane transporter activity
Z	0015108	molecular_function	chloride transmembrane transporter activity
Z	0015297	molecular_function	antiporter activity
Z	0015701	biological_process	bicarbonate transport
Z	0016020	cellular_component	membrane
Z	0016323	cellular_component	basolateral plasma membrane
Z	0030018	cellular_component	Z disc
Z	0030492	molecular_function	hemoglobin binding
Z	0030506	molecular_function	ankyrin binding
Z	0030863	cellular_component	cortical cytoskeleton
Z	0042803	molecular_function	protein homodimerization activity
Z	0043495	molecular_function	protein-membrane adaptor activity
Z	0051453	biological_process	regulation of intracellular pH
Z	0055085	biological_process	transmembrane transport
Z	0070062	cellular_component	extracellular exosome
Z	0072562	cellular_component	blood microparticle
Z	0140900	molecular_function	chloride:bicarbonate antiporter activity
Z	0170014	cellular_component	ankyrin-1 complex
Z	1902476	biological_process	chloride transmembrane transport
a	0016020	cellular_component	membrane
b	0016020	cellular_component	membrane
c	0016020	cellular_component	membrane
e	0005452	molecular_function	solute:inorganic anion antiporter activity
e	0005515	molecular_function	protein binding
e	0005737	cellular_component	cytoplasm
e	0005886	cellular_component	plasma membrane
e	0006811	biological_process	monoatomic ion transport
e	0006820	biological_process	monoatomic anion transport
e	0006821	biological_process	chloride transport
e	0006873	biological_process	intracellular monoatomic ion homeostasis
e	0008092	molecular_function	cytoskeletal protein binding
e	0008509	molecular_function	monoatomic anion transmembrane transporter activity
e	0009898	cellular_component	cytoplasmic side of plasma membrane
e	0015106	molecular_function	bicarbonate transmembrane transporter activity
e	0015108	molecular_function	chloride transmembrane transporter activity
e	0015297	molecular_function	antiporter activity
e	0015701	biological_process	bicarbonate transport
e	0016020	cellular_component	membrane
e	0016323	cellular_component	basolateral plasma membrane
e	0030018	cellular_component	Z disc
e	0030492	molecular_function	hemoglobin binding
e	0030506	molecular_function	ankyrin binding
e	0030863	cellular_component	cortical cytoskeleton
e	0042803	molecular_function	protein homodimerization activity
e	0043495	molecular_function	protein-membrane adaptor activity
e	0051453	biological_process	regulation of intracellular pH
e	0055085	biological_process	transmembrane transport
e	0070062	cellular_component	extracellular exosome
e	0072562	cellular_component	blood microparticle
e	0140900	molecular_function	chloride:bicarbonate antiporter activity
e	0170014	cellular_component	ankyrin-1 complex
e	1902476	biological_process	chloride transmembrane transport
f	0005452	molecular_function	solute:inorganic anion antiporter activity
f	0005515	molecular_function	protein binding
f	0005737	cellular_component	cytoplasm
f	0005886	cellular_component	plasma membrane
f	0006811	biological_process	monoatomic ion transport
f	0006820	biological_process	monoatomic anion transport
f	0006821	biological_process	chloride transport
f	0006873	biological_process	intracellular monoatomic ion homeostasis
f	0008092	molecular_function	cytoskeletal protein binding
f	0008509	molecular_function	monoatomic anion transmembrane transporter activity
f	0009898	cellular_component	cytoplasmic side of plasma membrane
f	0015106	molecular_function	bicarbonate transmembrane transporter activity
f	0015108	molecular_function	chloride transmembrane transporter activity
f	0015297	molecular_function	antiporter activity
f	0015701	biological_process	bicarbonate transport
f	0016020	cellular_component	membrane
f	0016323	cellular_component	basolateral plasma membrane
f	0030018	cellular_component	Z disc
f	0030492	molecular_function	hemoglobin binding
f	0030506	molecular_function	ankyrin binding
f	0030863	cellular_component	cortical cytoskeleton
f	0042803	molecular_function	protein homodimerization activity
f	0043495	molecular_function	protein-membrane adaptor activity
f	0051453	biological_process	regulation of intracellular pH
f	0055085	biological_process	transmembrane transport
f	0070062	cellular_component	extracellular exosome
f	0072562	cellular_component	blood microparticle
f	0140900	molecular_function	chloride:bicarbonate antiporter activity
f	0170014	cellular_component	ankyrin-1 complex
f	1902476	biological_process	chloride transmembrane transport
g	0005452	molecular_function	solute:inorganic anion antiporter activity
g	0005515	molecular_function	protein binding
g	0005737	cellular_component	cytoplasm
g	0005886	cellular_component	plasma membrane
g	0006811	biological_process	monoatomic ion transport
g	0006820	biological_process	monoatomic anion transport
g	0006821	biological_process	chloride transport
g	0006873	biological_process	intracellular monoatomic ion homeostasis
g	0008092	molecular_function	cytoskeletal protein binding
g	0008509	molecular_function	monoatomic anion transmembrane transporter activity
g	0009898	cellular_component	cytoplasmic side of plasma membrane
g	0015106	molecular_function	bicarbonate transmembrane transporter activity
g	0015108	molecular_function	chloride transmembrane transporter activity
g	0015297	molecular_function	antiporter activity
g	0015701	biological_process	bicarbonate transport
g	0016020	cellular_component	membrane
g	0016323	cellular_component	basolateral plasma membrane
g	0030018	cellular_component	Z disc
g	0030492	molecular_function	hemoglobin binding
g	0030506	molecular_function	ankyrin binding
g	0030863	cellular_component	cortical cytoskeleton
g	0042803	molecular_function	protein homodimerization activity
g	0043495	molecular_function	protein-membrane adaptor activity
g	0051453	biological_process	regulation of intracellular pH
g	0055085	biological_process	transmembrane transport
g	0070062	cellular_component	extracellular exosome
g	0072562	cellular_component	blood microparticle
g	0140900	molecular_function	chloride:bicarbonate antiporter activity
g	0170014	cellular_component	ankyrin-1 complex
g	1902476	biological_process	chloride transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. KYGFSSVGINLLVAAL

Chain	Residue	Details
L	LYS74-LEU89

---

site_id	PS00219
Number of Residues	12
Details	ANION_EXCHANGER_1 Anion exchangers family signature 1. FGGLVRDIRRRY

Chain	Residue	Details
V	PHE379-TYR390

---

site_id	PS00220
Number of Residues	15
Details	ANION_EXCHANGER_2 Anion exchangers family signature 2. FLISLIFIYETFsKL

Chain	Residue	Details
V	PHE526-LEU540

---

site_id	PS00312
Number of Residues	10
Details	GLYCOPHORIN_A Glycophorin A signature. IIlCVMAGII

Chain	Residue	Details
P	ILE66-ILE75
R	ILE95-ILE104

---

site_id	PS00547
Number of Residues	18
Details	TRANSGLUTAMINASES Transglutaminases active site. GQAWVlAAVacTvLRCLG

Chain	Residue	Details
X	GLY266-GLY283

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Repeat: {"description":"ANK 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	29
Details	Repeat: {"description":"ANK 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	29
Details	Repeat: {"description":"ANK 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	29
Details	Repeat: {"description":"ANK 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	27
Details	Repeat: {"description":"ANK 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	29
Details	Repeat: {"description":"ANK 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	29
Details	Repeat: {"description":"ANK 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	29
Details	Repeat: {"description":"ANK 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	29
Details	Repeat: {"description":"ANK 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	29
Details	Repeat: {"description":"ANK 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	29
Details	Repeat: {"description":"ANK 11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	29
Details	Repeat: {"description":"ANK 12"}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	29
Details	Repeat: {"description":"ANK 13"}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	29
Details	Repeat: {"description":"ANK 14"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	29
Details	Repeat: {"description":"ANK 15"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	29
Details	Repeat: {"description":"ANK 16"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	29
Details	Repeat: {"description":"ANK 17"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	29
Details	Repeat: {"description":"ANK 18"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	29
Details	Repeat: {"description":"ANK 19"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	29
Details	Repeat: {"description":"ANK 20"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	29
Details	Repeat: {"description":"ANK 21"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	29
Details	Repeat: {"description":"ANK 22"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	8
Details	Modified residue: {"description":"(3S)-3-hydroxyasparagine; by HIF1AN; partial","evidences":[{"source":"PubMed","id":"21177872","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"(3S)-3-hydroxyaspartate; by HIF1AN; partial","evidences":[{"source":"PubMed","id":"21177872","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	669
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	165
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	70
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	8
Details	Region: {"description":"Band 3 binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"PubMed","id":"8499466","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	132
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	138
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	492
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	450
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	96
Details	Transmembrane: {"description":"Discontinuously helical; Name=3","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	132
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	108
Details	Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	102
Details	Transmembrane: {"description":"Discontinuously helical; Name=10","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	108
Details	Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	180
Details	Intramembrane: {"description":"Discontinuously helical","evidences":[{"source":"PubMed","id":"26542571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	426
Details	Region: {"description":"Involved in anion transport"}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	6
Details	Site: {"description":"Important for anion transport"}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	6
Details	Site: {"description":"Important for anion-proton cotransport"}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"1998697","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	6
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"1885574","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"10861210","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24121512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35835865","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	27
Details	Region: {"description":"Interaction with ANK1","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P23562","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P04919","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	18
Details	Region: {"description":"(Microbial infection) Interaction with P.falciparum (isolate K1) FBPA","evidences":[{"source":"PubMed","id":"2204832","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"10942405","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1998697","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---