8CR3
Crystal structure of recombinant LasB from Pseudomonas aeruginosa PAO1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0015628 | biological_process | protein secretion by the type II secretion system |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0043952 | biological_process | protein transport by the Sec complex |
| A | 0044010 | biological_process | single-species biofilm formation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071978 | biological_process | bacterial-type flagellum-dependent swarming motility |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEVSHGF |
| Chain | Residue | Details |
| A | VAL137-PHE146 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"1899664","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"1899664","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"1899664","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"PDB data bank","title":"Elastase of Pseudomonas aeruginosa with an inhibitor.","authors":["Bitto E.","McKay D.B."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2008","submissionDatabase":"PDB data bank","title":"Structure of the elastase of Pseudomonas aeruginosa complexed with phosphoramidon.","authors":["Overgaard M.T.","McKay D.B."]}}]} |
| Chain | Residue | Details |
