8BSU
Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate and the positive allosteric modulator BPAM344 at 2.9A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| E | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| E | 0016020 | cellular_component | membrane |
| F | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| F | 0016020 | cellular_component | membrane |
| G | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| G | 0016020 | cellular_component | membrane |
| H | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| H | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21907808, ECO:0007744|PDB:3S9E |
| Chain | Residue | Details |
| A | PRO90 | |
| B | ALA143 | |
| B | THR144 | |
| B | GLU191 | |
| C | PRO90 | |
| C | THR92 | |
| C | ARG97 | |
| C | ALA143 | |
| C | THR144 | |
| C | GLU191 | |
| D | PRO90 | |
| A | THR92 | |
| D | THR92 | |
| D | ARG97 | |
| D | ALA143 | |
| D | THR144 | |
| D | GLU191 | |
| E | PRO90 | |
| E | THR92 | |
| E | ARG97 | |
| E | ALA143 | |
| E | THR144 | |
| A | ARG97 | |
| E | GLU191 | |
| F | PRO90 | |
| F | THR92 | |
| F | ARG97 | |
| F | ALA143 | |
| F | THR144 | |
| F | GLU191 | |
| G | PRO90 | |
| G | THR92 | |
| G | ARG97 | |
| A | ALA143 | |
| G | ALA143 | |
| G | THR144 | |
| G | GLU191 | |
| H | PRO90 | |
| H | THR92 | |
| H | ARG97 | |
| H | ALA143 | |
| H | THR144 | |
| H | GLU191 | |
| A | THR144 | |
| A | GLU191 | |
| B | PRO90 | |
| B | THR92 | |
| B | ARG97 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN5 | |
| E | ASN204 | |
| F | ASN5 | |
| F | ASN204 | |
| G | ASN5 | |
| G | ASN204 | |
| H | ASN5 | |
| H | ASN204 | |
| A | ASN204 | |
| B | ASN5 | |
| B | ASN204 | |
| C | ASN5 | |
| C | ASN204 | |
| D | ASN5 | |
| D | ASN204 | |
| E | ASN5 |
