8BDS

Ternary complex between VCB, BRD4-BD1 and PROTAC 48

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006368	biological_process	transcription elongation by RNA polymerase II
A	0030891	cellular_component	VCB complex
A	0070449	cellular_component	elongin complex
B	0006511	biological_process	ubiquitin-dependent protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00633
Number of Residues	60
Details	BROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY

Chain	Residue	Details
D	ALA80-TYR139

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Acetylated histone binding => ECO:0000269|PubMed:22464331

Chain	Residue	Details
D	ASN140

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	LYS99

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