8AS0
PD-1 extracellular domain in complex with Fab fragment from D12 antibody
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0050777 | biological_process | negative regulation of immune response |
| F | 0016020 | cellular_component | membrane |
| F | 0050777 | biological_process | negative regulation of immune response |
| I | 0016020 | cellular_component | membrane |
| I | 0050777 | biological_process | negative regulation of immune response |
| L | 0016020 | cellular_component | membrane |
| L | 0050777 | biological_process | negative regulation of immune response |
| O | 0016020 | cellular_component | membrane |
| O | 0050777 | biological_process | negative regulation of immune response |
| R | 0016020 | cellular_component | membrane |
| R | 0050777 | biological_process | negative regulation of immune response |
| X | 0016020 | cellular_component | membrane |
| X | 0050777 | biological_process | negative regulation of immune response |
| Y | 0016020 | cellular_component | membrane |
| Y | 0050777 | biological_process | negative regulation of immune response |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| B | TYR199-HIS205 | |
| C | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1168 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE24-VAL170 | |
| F | PHE24-VAL170 | |
| I | PHE24-VAL170 | |
| L | PHE24-VAL170 | |
| O | PHE24-VAL170 | |
| R | PHE24-VAL170 | |
| X | PHE24-VAL170 | |
| Y | PHE24-VAL170 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305|PubMed:28165004 |
| Chain | Residue | Details |
| A | ASN49 | |
| L | ASN49 | |
| L | ASN74 | |
| L | ASN116 | |
| O | ASN49 | |
| O | ASN74 | |
| O | ASN116 | |
| R | ASN49 | |
| R | ASN74 | |
| R | ASN116 | |
| X | ASN49 | |
| A | ASN74 | |
| X | ASN74 | |
| X | ASN116 | |
| Y | ASN49 | |
| Y | ASN74 | |
| Y | ASN116 | |
| A | ASN116 | |
| F | ASN49 | |
| F | ASN74 | |
| F | ASN116 | |
| I | ASN49 | |
| I | ASN74 | |
| I | ASN116 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28165004, ECO:0007744|PDB:5WT9 |
| Chain | Residue | Details |
| A | ASN58 | |
| F | ASN58 | |
| I | ASN58 | |
| L | ASN58 | |
| O | ASN58 | |
| R | ASN58 | |
| X | ASN58 | |
| Y | ASN58 |
