7ZL3
Signal peptide mimicry primes Sec61 for client-selective inhibition
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| B | 0006605 | biological_process | protein targeting |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0008320 | molecular_function | protein transmembrane transporter activity |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00755 |
| Number of Residues | 20 |
| Details | SECY_1 Protein secY signature 1. TLMaLGIsPIVtSGLIMQLL |
| Chain | Residue | Details |
| A | THR74-LEU93 |
| site_id | PS00756 |
| Number of Residues | 19 |
| Details | SECY_2 Protein secY signature 2. LLdElLQkgyGLGSGiSLF |
| Chain | Residue | Details |
| A | LEU163-PHE181 |
| site_id | PS01067 |
| Number of Residues | 29 |
| Details | SECE_SEC61G Protein secE/sec61-gamma signature. FvKDsIrlVkRctKPdrkEfqkiaMATAI |
| Chain | Residue | Details |
| B | PHE14-ILE42 |
