Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006508 | biological_process | proteolysis |
A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
A | 0008233 | molecular_function | peptidase activity |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
A | 0016567 | biological_process | protein ubiquitination |
A | 0016579 | biological_process | protein deubiquitination |
A | 0019784 | molecular_function | deNEDDylase activity |
A | 0030163 | biological_process | protein catabolic process |
A | 0043130 | molecular_function | ubiquitin binding |
A | 0043687 | biological_process | post-translational protein modification |
Functional Information from PROSITE/UniProt
site_id | PS00140 |
Number of Residues | 17 |
Details | UCH_1 Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site. QtisNACGtigLIHAIA |
Chain | Residue | Details |
A | GLN89-ALA105 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS95 | |
Chain | Residue | Details |
A | HIS169 | |
Chain | Residue | Details |
A | ASP184 | |
Chain | Residue | Details |
A | SER130 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 597 |
Chain | Residue | Details |
A | GLN89 | electrostatic stabiliser |
A | CYS95 | covalent catalysis, proton shuttle (general acid/base) |
A | HIS169 | proton shuttle (general acid/base) |
A | ASP184 | electrostatic stabiliser |