7WKV

Crystal structure of human ALKBH5 in complex with 2-oxoglutarate (2OG) and m6A-containing ssRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006397	biological_process	mRNA processing
A	0035515	molecular_function	oxidative RNA demethylase activity
A	0035553	biological_process	obsolete oxidative single-stranded RNA demethylation
C	0006397	biological_process	mRNA processing
C	0035515	molecular_function	oxidative RNA demethylase activity
C	0035553	biological_process	obsolete oxidative single-stranded RNA demethylation
E	0006397	biological_process	mRNA processing
E	0035515	molecular_function	oxidative RNA demethylase activity
E	0035553	biological_process	obsolete oxidative single-stranded RNA demethylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:24778178

Chain	Residue	Details
A	ASN193
A	ARG277
C	ASN193
C	ARG277
E	ASN193
E	ARG277

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site_id	SWS_FT_FI2
Number of Residues	9
Details	BINDING: BINDING => ECO:0000305|PubMed:24616105, ECO:0000305|PubMed:24778178

Chain	Residue	Details
A	HIS204
A	ASP206
A	HIS266
C	HIS204
C	ASP206
C	HIS266
E	HIS204
E	ASP206
E	HIS266

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site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS132
C	LYS132
E	LYS132

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