7W6A
Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0048188 | cellular_component | Set1C/COMPASS complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983 |
| Chain | Residue | Details |
| F | SER350 | |
| C | ARG3841 | |
| C | ASN3959 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00190, ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:26886794, ECO:0007744|PDB:2W5Z, ECO:0007744|PDB:5F5E |
| Chain | Residue | Details |
| C | TYR3884 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:26886794, ECO:0007744|PDB:2W5Y, ECO:0007744|PDB:5F5E, ECO:0007744|PDB:5F6L |
| Chain | Residue | Details |
| C | ASN3907 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16990798, ECO:0000269|PubMed:19187761, ECO:0007744|PDB:2W5Y, ECO:0007744|PDB:2W5Z, ECO:0007744|PDB:5F5E, ECO:0007744|PDB:5F6L |
| Chain | Residue | Details |
| C | CYS3910 | |
| C | CYS3958 | |
| C | CYS3960 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16990798, ECO:0000269|PubMed:19187761, ECO:0007744|PDB:2W5Y, ECO:0007744|PDB:2W5Z, ECO:0007744|PDB:5F6L |
| Chain | Residue | Details |
| C | CYS3965 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: S-methylcysteine; by autocatalysis => ECO:0000269|PubMed:24235145 |
| Chain | Residue | Details |
| C | SER3883 |
